Zobrazeno 1 - 10
of 297
pro vyhledávání: '"Human embryonic stem cell line"'
Autor:
Changqing Zeng, Amir Abliz, Yaqiang Hong, Xinchang Zheng, Zhen Wu, Xiaonan Guan, Qianfei Wang, Mengfei Liu, Qingtao Hu, Aili Chen, Fuxin Zhao, Jian Bai, Shaoyan Hu, Hong Cai, Wei Chen, Junting Zhang, Xiangtian Zhou, Dake Zhang, Yang Ke, Kenan Gong, Yue Ma, Hongzhu Qu, Liang Wang, Shujuan Lai, Shuang Hao
Publikováno v:
Genomics, Proteomics & Bioinformatics. 20:177-191
Postzygotic mutations are acquired in normal tissues throughout an individual's lifetime and hold clues for identifying mutagenic factors. Here, we investigated postzygotic mutation spectra of healthy individuals using optimized ultra-deep exome sequ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51b246599704da48424c0c81cefb1cd3
https://doi.org/10.1016/j.gpb.2021.09.005
https://doi.org/10.1016/j.gpb.2021.09.005
Autor:
Kamal Kamal, I. Richard Thompson, Rudolf Engelke, Neha Goswami, Mohamed Emara, Sara A. Abdulla, Muna N. Al-Noubi, Freshteh Palangi, Frank Schmidt, Salam Salloum-Asfar, Hanaa Mousa
Publikováno v:
Stem Cells International
Stem Cells International, Vol 2021 (2021)
Stem Cells International, Vol 2021 (2021)
Stress granules (SGs) are assemblies of selective messenger RNAs (mRNAs), translation factors, and RNA-binding proteins in small untranslated messenger ribonucleoprotein (mRNP) complexes in the cytoplasm. Evidence indicates that different types of ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca7de8343751871203e087abc267ba43
https://doi.org/10.1155/2021/8274936
https://doi.org/10.1155/2021/8274936
Autor:
Vassilis Valatas, George Kolios, Leonidas Kandilogiannakis, Stylianos Didaskalou, Vasilis Paspaliaris, Maria Koffa, Ioannis Drygiannakis, Konstantinos Arvanitidis, G Tarapatzi, Giorgos Bamias, Eirini Filidou
Publikováno v:
Stem Cells International, Vol 2021 (2021)
Inflammatory Bowel Diseases (IBDs) are characterized by chronic intestinal inflammation and fibrosis, the latter being the predominant denominator for long-term complications. Epithelial and mesenchymal 2D cultures are highly utilized in vitro models
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa82651435711888af581fb0e9870fc3
https://doi.org/10.1155/2021/9929461
https://doi.org/10.1155/2021/9929461
Autor:
Xuan Ni, Lingqun Ye, Zhen-Ao Zhao, Miao Yu, Wei Lei, Xing Fang, Yongming Wang, Yong Wang, Shijun Hu, Ying Chen, You Yu, Zhenya Shen, Jun-Ming Tang, Dandan Zhao
Publikováno v:
Cardiovascular Research. 118:859-871
Aims Congenital heart disease (CHD) frequently occurs in newborns due to abnormal formation of the heart or major blood vessels. Mutations in the GATA4 gene, which encodes GATA binding protein 4, are responsible for atrial septal defect (ASD), a comm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9dcafd38b311a3e2871de3bd212a4489
https://doi.org/10.1093/cvr/cvab154
https://doi.org/10.1093/cvr/cvab154
Transcriptomic Profiling of Human Pluripotent Stem Cell-derived Retinal Pigment Epithelium over Time
Autor:
Alice Pébay, Erica L. Fletcher, Daniela Amann-Zalcenstein, Shalin H. Naik, Anne Senabouth, Casey J.A. Smith-Anttila, Vikkitharan Gnanasambandapillai, Grace E. Lidgerwood, Dominik C. Kaczorowski, Joseph E. Powell, Alex W. Hewitt
Publikováno v:
Genomics, Proteomics & Bioinformatics, Vol 19, Iss 2, Pp 223-242 (2021)
Genomics, Proteomics & Bioinformatics
Genomics, Proteomics & Bioinformatics
Human pluripotent stem cell (hPSC)-derived progenies are immature versions of cells, presenting a potential limitation to the accurate modelling of disease associated with maturity or age. Hence, it is important to characterise how closely cells used
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcc32b7a12cf9deec42b6968d4df447c
http://www.sciencedirect.com/science/article/pii/S1672022920301352
http://www.sciencedirect.com/science/article/pii/S1672022920301352
Autor:
Wen-Jing Lu, Rui Bai, Feng Lan, Mengqi Jiang, Chengwen Hang, Ming Cui, Amina Saleem, Ya'nan Li, Siyao Zhang, Yuanxiu Song, Yun Chang
Publikováno v:
Journal of Cellular and Molecular Medicine
Myomesin‐1 (encoded by MYOM1 gene) is expressed in almost all cross‐striated muscles, whose family (together with myomesin‐2 and myomesin‐3) helps to cross‐link adjacent myosin to form the M‐line in myofibrils. However, little is known ab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8117d129c52b71a4aeb021b0d743b629
https://doi.org/10.1111/jcmm.16268
https://doi.org/10.1111/jcmm.16268
Publikováno v:
Human Reproduction. 35:1120-1129
STUDY QUESTION Is the mitochondrial DNA (mtDNA) copy number of cumulus granulosa cells (CGCs) related to the maturation of oocyte cytoplasm? SUMMARY ANSWER Compared with the mtDNA copy number of CGCs from germinal vesicles (GV), CGCs from Metaphase I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19d1fc2924bedae72fa702d2dcb0e5dc
https://doi.org/10.1093/humrep/deaa085
https://doi.org/10.1093/humrep/deaa085
Autor:
Jordi Alberch, Phil Sanders, Jordi Carrere, Josep M. Canals, Joan Blasi, Javier G. Orlandi, Andrea Comella-Bolla, Marco Straccia, Nicholas D. Allen, María García-Bravo, Georgina Bombau, José C. Segovia, Andrés Miguez, Jordi Soriano, Mireia Galofré
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Molecular Neurobiology
Universidad de Barcelona
Molecular Neurobiology
Human pluripotent stem cells (hPSCs) are a powerful tool for modelling human development. In recent years, hPSCs have become central in cell-based therapies for neurodegenerative diseases given their potential to replace affected neurons. However, di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c561875e7de52beb4260fd1b5a68277b
https://doi.org/10.1007/s12035-020-01907-4
https://doi.org/10.1007/s12035-020-01907-4
Autor:
Wei Huang, Hua-Dong Wang, Jing-Bo Wang, Ning Li, Xiaofei Yang, Fei He, Hai-Bo Huang, Fu-Rong Li
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-12 (2020)
Stem Cell Research & Therapy
Stem Cell Research & Therapy
Background Human embryonic stem cells represent a potentially unlimited source of insulin-producing cells for diabetes therapy. While tremendous progress has been made in directed differentiation of human embryonic stem cells into IPCs in vitro, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9005428e473523ee8331573dbaac19c
http://link.springer.com/article/10.1186/s13287-020-01674-y
http://link.springer.com/article/10.1186/s13287-020-01674-y
Publikováno v:
Letters in Oncology Science. 17:37-46
Introduction: The osteoarthritis is a serious threat for well-developed and ageing countries. Present techniques of treatment of damaged cartilage are not sufficient. Hence, new strategies should be developed. One of the potential sources for the reg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d95d5a37479bb9878ffefb38b4e7b2ae
https://doi.org/10.21641/los.2020.17.1.169
https://doi.org/10.21641/los.2020.17.1.169