Zobrazeno 1 - 10
of 472
pro vyhledávání: '"Human brain tissue"'
Autor:
Oleksandr Gakh, Jordan M. Wilkins, Yong Guo, Bogdan F. Popescu, Stephen D. Weigand, Alicja Kalinowska-Lyszczarz, Claudia F. Lucchinetti
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-14 (2024)
Abstract Multiple sclerosis (MS) is a leading cause of non-traumatic disability in young adults. The highly dynamic nature of MS lesions has made them difficult to study using traditional histopathology due to the specificity of current stains. This
Externí odkaz:
https://doaj.org/article/fd7c32d747bb4478823c32f309bb1bfd
Autor:
Sofia Nevelchuk, Bianca Brawek, Niklas Schwarz, Ariel Valiente-Gabioud, Thomas V. Wuttke, Yury Kovalchuk, Henner Koch, Anke Höllig, Frederik Steiner, Katherine Figarella, Oliver Griesbeck, Olga Garaschuk
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-18 (2024)
Abstract Background Key functions of Ca2+ signaling in rodent microglia include monitoring the brain state as well as the surrounding neuronal activity and sensing the danger or damage in their vicinity. Microglial Ca2+ dyshomeostasis is a disease ha
Externí odkaz:
https://doaj.org/article/f59d308c1bb54804afb0a503847e6608
Microglial proliferation and astrocytic protein alterations in the human Huntington's disease cortex
Autor:
Adelie Y.S. Tan, Lynette J. Tippett, Clinton P. Turner, Molly E.V. Swanson, Thomas I.H. Park, Maurice A. Curtis, Richard L.M. Faull, Mike Dragunow, Malvindar K. Singh-Bains
Publikováno v:
Neurobiology of Disease, Vol 198, Iss , Pp 106554- (2024)
Huntington's disease (HD) is a neurodegenerative disorder that severely affects the basal ganglia and regions of the cerebral cortex. While astrocytosis and microgliosis both contribute to basal ganglia pathology, the contribution of gliosis and pote
Externí odkaz:
https://doaj.org/article/b55a6aaec4d04011a25fb03e9a9414ad
Publikováno v:
BMC Medical Genomics, Vol 17, Iss 1, Pp 1-14 (2024)
Abstract Background In the ICU ward, septic cirrhotic patients are susceptible to suffering from sepsis-associated encephalopathy and/or hepatic encephalopathy, which are two common neurological complications in such patients. However, the mutual pat
Externí odkaz:
https://doaj.org/article/19d0d6d3309745d69685b529f8289214
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
Inverse mechanical parameter identification enables the characterization of ultrasoft materials, for which it is difficult to achieve homogeneous deformation states. However, this usually involves high computational costs that are mainly determined b
Externí odkaz:
https://doaj.org/article/d952d27d74804e35bcffe060f9d62f34
Autor:
Sarah Woelfle, Dhruva Deshpande, Simone Feldengut, Heiko Braak, Kelly Del Tredici, Francesco Roselli, Karl Deisseroth, Jens Michaelis, Tobias M. Boeckers, Michael Schön
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-28 (2023)
Abstract Background Post mortem human brain tissue is an essential resource to study cell types, connectivity as well as subcellular structures down to the molecular setup of the central nervous system especially with respect to the plethora of brain
Externí odkaz:
https://doaj.org/article/2fa2b3278a9241a7b0218406d99828a4
Publikováno v:
Applications in Engineering Science, Vol 15, Iss , Pp 100130- (2023)
We develop new rate-type constitutive relations on a set of orthonormal tensor basis and the corresponding set of Lode invariants, which require only 9 material parameters to predict the mechanical response of the human brain tissue. The mode-depende
Externí odkaz:
https://doaj.org/article/46b366d9bc17423fb79fb2e669130d7d
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