Zobrazeno 1 - 10
of 90 225
pro vyhledávání: '"Human brain"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-24 (2024)
Abstract The human brain’s distinctive folding pattern has attracted the attention of researchers from different fields. Neuroscientists have provided insights into the role of four fundamental cell types crucial during embryonic development: radia
Externí odkaz:
https://doaj.org/article/73655fe51c3241aa95e2633ce8812e6e
Autor:
Wenjuan Chen
Publikováno v:
BMC Cardiovascular Disorders, Vol 24, Iss 1, Pp 1-6 (2024)
Abstract Background Heart failure in elderly individuals poses significant challenges due to the decline in cardiac function associated with aging. This study aimed to investigate the clinical efficacy of recombinant human brain natriuretic peptide (
Externí odkaz:
https://doaj.org/article/678b2451335a48e4abab344abd7bf4eb
Autor:
Oleksandr Gakh, Jordan M. Wilkins, Yong Guo, Bogdan F. Popescu, Stephen D. Weigand, Alicja Kalinowska-Lyszczarz, Claudia F. Lucchinetti
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-14 (2024)
Abstract Multiple sclerosis (MS) is a leading cause of non-traumatic disability in young adults. The highly dynamic nature of MS lesions has made them difficult to study using traditional histopathology due to the specificity of current stains. This
Externí odkaz:
https://doaj.org/article/fd7c32d747bb4478823c32f309bb1bfd
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Background Alzheimer disease (AD) is a heterogenous and multifactorial disease, and its pathology is partly driven by microglia and their activated phenotype. Brain organoids (BOs) are gaining prominence as a relevant model of the human brai
Externí odkaz:
https://doaj.org/article/42fb4bcc72914191ac8dbebc4e321cdf
Autor:
Sofia Nevelchuk, Bianca Brawek, Niklas Schwarz, Ariel Valiente-Gabioud, Thomas V. Wuttke, Yury Kovalchuk, Henner Koch, Anke Höllig, Frederik Steiner, Katherine Figarella, Oliver Griesbeck, Olga Garaschuk
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-18 (2024)
Abstract Background Key functions of Ca2+ signaling in rodent microglia include monitoring the brain state as well as the surrounding neuronal activity and sensing the danger or damage in their vicinity. Microglial Ca2+ dyshomeostasis is a disease ha
Externí odkaz:
https://doaj.org/article/f59d308c1bb54804afb0a503847e6608
Autor:
Curzio Checcucci, Bridget Wicinski, Giacomo Mazzamuto, Marina Scardigli, Josephine Ramazzotti, Niamh Brady, Francesco S. Pavone, Patrick R. Hof, Irene Costantini, Paolo Frasconi
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract 3D reconstruction of human brain volumes at high resolution is now possible thanks to advancements in tissue clearing methods and fluorescence microscopy techniques. Analyzing the massive data produced with these approaches requires automati
Externí odkaz:
https://doaj.org/article/7a03e70b94084892bc125093f3c41c3b
Autor:
Diana Wiesner, Simone Feldengut, Sarah Woelfle, Tobias M. Boeckers, Albert C. Ludolph, Francesco Roselli, Kelly Del Tredici
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-22 (2024)
Abstract We quantified and determined for the first time the distribution pattern of the neuropeptide NPFF in the human cerebral cortex and subjacent white matter. To do so, we studied n = 9 cases without neurological disorders and n = 22 cases with
Externí odkaz:
https://doaj.org/article/c3df8e596f764abb92e9e459617579ea
Autor:
YIN Kuiying, YU Tao
Publikováno v:
Zhihui kongzhi yu fangzhen, Vol 46, Iss 3, Pp 1-11 (2024)
We are embracing the fourth wave of human development, which is a critical transition from the information society to an intelligent society integrating human beings, the physical world, and the cyberspace. In recent years, computing and information
Externí odkaz:
https://doaj.org/article/ea434f7e227e452eaf1fbc149f4d3036