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pro vyhledávání: '"Human Proteome Project"'
Akademický článek
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Akademický článek
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Autor:
Chun Wu, Xiaolong Lu, Shaohua Lu, Hongwei Wang, Dehua Li, Jing Zhao, Jingjie Jin, Zhenghua Sun, Qing-Yu He, Yang Chen, Gong Zhang
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Alternative splicing (AS) isoforms create numerous proteoforms, expanding the complexity of the genome. Highly similar sequences, incomplete reference databases and the insufficient sequence coverage of mass spectrometry limit the identification of A
Externí odkaz:
https://doaj.org/article/7711bc3c85114c8fada70609b8152f0a
Autor:
George Krasnov, Timur Shkrigunov, Sergey Radko, Konstantin Ptitsyn, Valeriya Shapovalova, Olga Timoshenko, Svetlana Khmeleva, Leonid Kurbatov, Yana Kiseleva, Ekaterina Ilgisonis, Olga Kiseleva, Igor Vakhrushev, Anastasia Tsvetkova, Ivan Buromski, Sergey Markin, Alexander Archakov, Andrey Lisitsa, Elena Ponomarenko
Publikováno v:
Data in Brief, Vol 36, Iss , Pp 107130- (2021)
The chromosome-centric dataset was created by applying several technologies of transcriptome profiling. The described dataset is available at NCBI repository (BioProject ID PRJNA635536). The dataset referred to the same type of tissue, cell lines, tr
Externí odkaz:
https://doaj.org/article/3c58741049114b1294ba50cbe8cbb649
Autor:
Gilbert S. Omenn, Lydie Lane, Christopher M. Overall, Charles Pineau, Nicolle H. Packer, Ileana M. Cristea, Cecilia Lindskog, Susan T. Weintraub, Sandra Orchard, Michael H. A. Roehrl, Edouard Nice, Siqi Liu, Nuno Bandeira, Yu-Ju Chen, Tiannan Guo, Ruedi Aebersold, Robert L. Moritz, Eric W. Deutsch
Publikováno v:
J Proteome Res
Journal of Proteome Research
Journal of Proteome Research, 2023, 22 (4), pp.1024-1042. ⟨10.1021/acs.jproteome.2c00498⟩
Journal of Proteome Research
Journal of Proteome Research, 2023, 22 (4), pp.1024-1042. ⟨10.1021/acs.jproteome.2c00498⟩
International audience; The 2022 Metrics of the Human Proteome from the HUPO Human Proteome Project (HPP) illustrates that protein expression has now been credibly detected (neXtProt PE1 level) for 18,407 (93.2%) of the 19,750 predicted proteins code
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e66761c62e4ef4d973a5ffb5979673de
https://doi.org/10.1021/acs.jproteome.2c00498
https://doi.org/10.1021/acs.jproteome.2c00498
Autor:
Alicia Landeira-Viñuela, Paula Díez, Pablo Juanes-Velasco, Quentin Lécrevisse, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes
Publikováno v:
Biomolecules, Vol 11, Iss 12, p 1776 (2021)
Human Proteome Project (HPP) presents a systematic characterization of the protein landscape under different conditions using several complementary-omic techniques (LC-MS/MS proteomics, affinity proteomics, transcriptomics, etc.). In the present stud
Externí odkaz:
https://doaj.org/article/556d281facd54cecb22447663535af64
Publikováno v:
ACS chemical neuroscience. 13(15)
Effectively presenting epitopes on immunogens, in order to raise conformationally selective antibodies through active immunization, is a central problem in treating protein misfolding diseases, particularly neurodegenerative diseases such as Alzheime
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bf178de31c0a9368cf412ab7189e916
https://pubmed.ncbi.nlm.nih.gov/35840132
https://pubmed.ncbi.nlm.nih.gov/35840132
Autor:
Dariusz Plewczynski, Anup Kumar Halder, Subhadip Basu, Mita Nasipuri, Soumyendu Sekhar Bandyopadhyay, Piyali Chatterjee
Publikováno v:
IEEE/ACM Transactions on Computational Biology and Bioinformatics. 19:531-542
Over the years, several methods have been proposed for the computational PPI prediction with different performance evaluation strategies. While attempting to benchmark performance scores, most of these methods often suffer with ill-treated cross-vali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b882ceda69d657d290a60ea6f9a749a4
https://doi.org/10.1109/tcbb.2020.3004970
https://doi.org/10.1109/tcbb.2020.3004970
Publikováno v:
NAR Genomics and Bioinformatics. 5
The correct mapping of the proteome is an important step towards advancing our understanding of biological systems and cellular mechanisms. Methods that provide better mappings can fuel important processes such as drug discovery and disease understan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd7028fdbec0c7557cc38397bc4b18cd
https://doi.org/10.1093/nargab/lqad021
https://doi.org/10.1093/nargab/lqad021
Autor:
Laura Guerrero, Bruno Sangro, Verónica Ambao, José Ignacio Granero, Antonio Ramos-Fernández, Alberto Paradela, Fernando J. Corrales
Publikováno v:
Journal of Physiology and Biochemistry
Precision medicine promises to overcome the constraints of the traditional “one-for-all” healthcare approach through a clear understanding of the molecular features of a disease, allowing for innovative and tailored treatments. State-of-the-art p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8ed8ec6adc4cf958261786ae42e4719
http://europepmc.org/articles/PMC8666175
http://europepmc.org/articles/PMC8666175