Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Human Pancreatic Growth Hormone-Releasing Factor"'
Publikováno v:
International Journal of Peptide and Protein Research. 24:498-504
The human growth hormone-releasing factor (GRF) peptides [GlyS15]-GRF-(1–15) (IV), trifluoroacetyl-GRF-(20–44) (VI), trifluoroacetyl-GRF-(18–44) (VIII), and trifluoroacetyl-GRF-(16–44) (X) were synthesized by the solid-phase method. Each of t
Publikováno v:
Neuroscience. 258
Although it is a general consensus that opioids modulate growth, the mechanism of this phenomenon is largely unknown. Since endogenous opiates use the same receptor family as morphine, these peptides may be one of the key regulators of growth in huma
Autor:
Justo P. Castaño, Pablo M. Dobado-Berrios, María M. Malagón, Socorro García-Navarro, Francisco Gracia-Navarro
Publikováno v:
General and Comparative Endocrinology. 84:461-469
Subcellular responses of amphibian growth hormone (GH)-producing cells to in vivo administration of human pancreatic growth hormone-releasing factor (1-44) (hpGRF) were investigated. The volume density (Vv) of secretory granules (SG), rough endoplasm
Autor:
Colin G. Scanes, S. Harvey
Publikováno v:
Neuroendocrinology. 39:314-320
Plasma concentrations of growth hormone (GH) were elevated in anaesthetized male domestic fowl following the intravenous administration of either synthetic human pancreatic GH-releasing factor 1-44 (NH2) (hpGRF) or synthetic thyrotrophin-releasing ho
Autor:
S. Harvey, C.G. Scanes
Publikováno v:
General and Comparative Endocrinology. 59:10-14
In anaesthetized young (6 weeks old) and adult (22-30 weeks old) domestic fowl, the administration of thyrotrophin releasing hormone (TRH; 1.0 micrograms/kg in young birds; 10.0 micrograms/kg in adults) or human pancreatic growth hormone-releasing fa
Publikováno v:
Biochemical and Biophysical Research Communications. 112:469-474
Synthetic human pancreatic growth hormone-releasing factor containing 40 amino acids ([hpGRF (1-40)]-OH) significantly stimulated plasma growth hormone (GH) levels in both sodium pentobarbital and urethane anesthetized rats. Synthetic secretin, gastr
Autor:
H. W. Harpster, J. F. Kavanaugh, B. R. Schricker, M. L. Maccecchini, R. S. Kensinger, R. K. Stover, L. M. McMunn
Publikováno v:
Journal of Animal Science. 64:1002-1009
Two experiments were performed to examine the ability of human pancreatic growth hormone releasing factor (hGRF) administration to stimulate endogenous growth hormone (GH) secretion in lambs. Each study utilized eight Dorset wether lambs in replicate
Publikováno v:
Biochemical and Biophysical Research Communications. 124:217-222
The aim of this study was to investigate whether anterior pituitary responsiveness to human pancreatic growth hormone-releasing factor containing 29 amino acids (GRF-29) can be modulated by GRF-29 itself. Male rats were injected (sc) daily for 3 days
Publikováno v:
Journal of Medicinal Chemistry. 28:181-185
In previous reports illustrating the effects of conformational restriction of the N-terminal region of human pancreatic growth hormone releasing factor, we demonstrated that D-amino acid substitutions in either of positions 1, 2, or 3 resulted in gre