Zobrazeno 1 - 10
of 1 239
pro vyhledávání: '"Human Leukocyte Antigen (HLA)."'
Autor:
Zi-Xuan Rong, Wei Wei, Qin Zeng, Xiao-Ting Cai, Yuan-Yuan Wang, Jian Wang, He-San Luo, Lu-Shan Xiao, Jia-Run Lin, Xue Bai, Yan-Pei Zhang, Duan-Duan Han, Zhong-Yi Dong, Wei Wang, De-Hua Wu, Si-Cong Ma
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-12 (2024)
Abstract Background Up to 17% of cancer survivors have been reported to develop second primary cancers (SPC), which cause significant physical and economic distress and often complicate clinical decision-making. However, understanding of SPC remains
Externí odkaz:
https://doaj.org/article/b553b1c91f8c4099bd5a9f06ee563c12
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Human herpes viruses (HHV) are ubiquitous and have been implicated in numerous long-term health conditions. Since the association between viral exposure and long-term health impacts is partially influenced by variation in human leukocyte ant
Externí odkaz:
https://doaj.org/article/b490cbc72d5c47d7afc09b416a380d1f
Autor:
Yasunari Matsuzaka, Ryu Yashiro
Publikováno v:
BioMedInformatics, Vol 4, Iss 3, Pp 1835-1864 (2024)
Human Leukocyte Antigen (HLA) is like a device that monitors the internal environment of the body. T lymphocytes immediately recognize the HLA molecules that are expressed on the surface of the cells of the different individual, attacking it defeats
Externí odkaz:
https://doaj.org/article/0c7ad812977745b7b1735227639ecfee
Autor:
Raya Saleh, Erik Sundberg, Mia Olsson, Katarina Tengvall, Lars Alfredsson, Ingrid Kockum, Leonid Padyukov, Helena Erlandsson Harris
Publikováno v:
Pediatric Rheumatology Online Journal, Vol 22, Iss 1, Pp 1-12 (2024)
Abstract Background Juvenile Idiopathic Arthritis (JIA) is a complex autoimmune disease and the most common chronic rheumatological disease affecting children under the age of 16. The etiology of JIA remains poorly understood, but evidence suggests a
Externí odkaz:
https://doaj.org/article/d8bc63d7b96a48848186f553c014605d
Autor:
Sheng-Kai Lai, Allen Chilun Luo, I-Hsuan Chiu, Hui-Wen Chuang, Ting-Hsuan Chou, Tsung-Kai Hung, Jacob Shujui Hsu, Chien-Yu Chen, Wei-Shiung Yang, Ya-Chien Yang, Pei-Lung Chen
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 1562-1571 (2024)
Human leukocyte antigen (HLA) genes play pivotal roles in numerous immunological applications. Given the immense number of polymorphisms, achieving accurate high-throughput HLA typing remains challenging. This study aimed to harness the human pan-gen
Externí odkaz:
https://doaj.org/article/08955c6a50a74592a2f382097a0b670e
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Several viruses have been implicated in breast cancer, including human herpes virus 4 (HHV4), human herpes virus 5 (HHV5), human papilloma virus (HPV), human JC polyoma virus (JCV), human endogenous retrovirus group K (HERVK), bovine leukemi
Externí odkaz:
https://doaj.org/article/f825e369e92d49a6bf72f56eafa36f3b
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionThe human leukocyte antigen (HLA) evolutionary divergence (HED) reflects immunopeptidome diversity and has been shown to predict the response of tumors to immunotherapy. Its impact on allogeneic hematopoietic stem cell transplantation (HS
Externí odkaz:
https://doaj.org/article/274514776a674a298a6f67f2f7dded03
Autor:
Jiancheng Huang, Mingkuan Su, Fanhui Kong, Hongbin Chen, Shuiqing Wu, Jianfeng Guo, Haiying Wu
Publikováno v:
Liver Research, Vol 8, Iss 1, Pp 54-60 (2024)
Background and aim: A genome-wide association study has indicated the association of numerous genes in the 6p21.3 region with chronic hepatitis B virus (HBV) infection. In this study, we screened 12 representative single-nucleotide polymorphisms (SNP
Externí odkaz:
https://doaj.org/article/e92a52a76e124bb4a52554c7fb7f58b0
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract The Human leukocyte antigen (HLA) molecules are central to immune response and have associations with the phenotypes of various diseases and induced drug toxicity. Further, the role of HLA molecules in presenting antigens significantly affec
Externí odkaz:
https://doaj.org/article/0041fad8ddf94651a1d3d8d9cf895583
Autor:
Amène Ben Bnina, Amri Yessine, Yasmine El Bahri, Saoussen Chouchene, Nada Ben Lazrek, Mariem Mimouna, Zeineb Mlika, Aziza Messoudi, Dorsaf Zellama, Wissal Sahtout, Amina Bouatay
Publikováno v:
BMC Medical Genomics, Vol 17, Iss 1, Pp 1-14 (2024)
Abstract Background Estimation of HLA (Human leukocyte Antigen) alleles’ frequencies in populations is essential to explore their ethnic origin. Anthropologic studies of central Tunisian population were rarely reported. Then, in this work, we aimed
Externí odkaz:
https://doaj.org/article/47143686edac45c397bc26950ffb0d6a