Zobrazeno 1 - 10
of 436
pro vyhledávání: '"Human Lens Epithelial Cells"'
Publikováno v:
International Journal of Ophthalmology, Vol 17, Iss 7, Pp 1205-1216 (2024)
AIM: To explore the effect of silent information regulator factor 2-related enzyme 1 (SIRT1) on modulating apoptosis of human lens epithelial cells (HLECs) and alleviating lens opacification of rats through suppressing endoplasmic reticulum (ER) stre
Externí odkaz:
https://doaj.org/article/d9c41c11d496407686807bd4bd1195ba
Publikováno v:
International Journal of Ophthalmology, Vol 16, Iss 12, Pp 1935-1941 (2023)
AIM: To investigate the role of reactive oxygen species (ROS) in epithelial–mesenchymal transition (EMT) and apoptosis of human lens epithelial cells (HLECs). METHODS: Flow cytometry was used to assess ROS production after transforming growth facto
Externí odkaz:
https://doaj.org/article/a9f3f91aa4974677a96c5a0cbc9ec09f
Publikováno v:
Guoji Yanke Zazhi, Vol 23, Iss 7, Pp 1072-1079 (2023)
AIM: To investigate the mechanism of pyrrolidine dithiocarbamate(PDTC)on transforming growth factor-beta 2(TGF-β2)-induced epithelial-mesenchymal transition(EMT)in human lens epithelial cells(LECs).METHODS: LECs were treated with various doses of PD
Externí odkaz:
https://doaj.org/article/cca188880f9441499bae56c726dc3621
Publikováno v:
Heliyon, Vol 10, Iss 1, Pp e23690- (2024)
Purpose: To investigated the biological effects of E156K-mutated αA-crystallin (CRYAA) in human lens epithelial cells (HLECs). Methods: FLAG-tagged, human, full-length, wild-type (WT), or E156K-mutated CRYAA was expressed in HLECs under CRYAA knockd
Externí odkaz:
https://doaj.org/article/71d2ab73c134460d96d0228fc6188f2d
Autor:
Jiasheng Liu, Mengchao Zhu, Yitong Xu, Mengdi Zhang, Haisen Sun, Yaqi Wang, Qingwen Yang, Jin Li
Publikováno v:
BMC Ophthalmology, Vol 23, Iss 1, Pp 1-7 (2023)
Abstract Background Autophagy is an important process that maintains the quality of intracellular proteins and organelles. There is extensive evidence that autophagy has an important role in the lens. Human lens epithelial cells (HLECs) play a key ro
Externí odkaz:
https://doaj.org/article/6deb7687339649659bf94d464d75f473
Publikováno v:
Guoji Yanke Zazhi, Vol 23, Iss 4, Pp 551-556 (2023)
AIM: To investigate the changes of protein expressions in human lens epithelial cells(SRA01/04)undergoing oxidative damage, hoping to provide new protein target for the pathogenesis of age-related cataract(ARC).METHODS: SRA01/04 cells were divided in
Externí odkaz:
https://doaj.org/article/7b712a1894e749b18dfe9dac39ca681e
Autor:
Pei-Yuan Wu, Ning Ji, Chong-Guang Wu, Xiao-Die Wang, Xin Liu, Zhi-Xue Song, Murad Khan, Suleman Shah, Ying-Hua Du, Xiu-Fang Wang, Li-Fang Yan
Publikováno v:
International Journal of Ophthalmology, Vol 16, Iss 2, Pp 178-190 (2023)
AIM: To determine whether an antisense RNA corresponding to the human Alu transposable element (Aluas RNA) can protect human lens epithelial cells (HLECs) from methylglyoxal-induced apoptosis. METHODS: Cell counting kit-8 (CCK-8) and 3-(4,5-Dimethylt
Externí odkaz:
https://doaj.org/article/39990438e917441a8bf5af6ec7ea0513
Autor:
Dongyan Zhang, Hong Zhu, Xin Yu, Liyin Wang, Yingying Wen, Liyue Zhang, Jianping Tong, Ye Shen
Publikováno v:
BMC Ophthalmology, Vol 22, Iss 1, Pp 1-14 (2022)
Abstract Background Pathogenesis of posterior capsular opacification (PCO) was related to pathological epithelial-mesenchymal transition (EMT) of lens epithelial cells (LECs). It has been reported that blue light could have an effect on EMT. This stu
Externí odkaz:
https://doaj.org/article/c706d7aa68a44fd1b001b768a169b69b
Publikováno v:
International Journal of Ophthalmology, Vol 15, Iss 1, Pp 9-14 (2022)
AIM: To investigate the effect of nano-selenium loaded with different concentrations of lycium barbarum polysaccharide (LBP-SeNPs) on the proliferation of human lens epithelial cells (HLECs) from UV irradiation. METHODS: LBP-SeNPs were prepared and t
Externí odkaz:
https://doaj.org/article/38aa4fb4ce824a9e9aa8df1dabbcdd45
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