Zobrazeno 1 - 1
of 1
pro vyhledávání: '"Human Growth Hormone/genetics/secretion"'
Autor:
P. A. Antinozzi, Claes B. Wollheim, M. Iezzi, Sten Theander, Haiyan Wang, Philippe A. Halban, Benoit R. Gauthier
Publikováno v:
Diabetologia, Vol. 48, No 4 (2005) pp. 720-731
AIMS/HYPOTHESIS: Mutations in genes encoding HNF-4alpha, HNF-1alpha and IPF-1/Pdx-1 are associated with, respectively, MODY subtypes-1, -3 and -4. Impaired glucose-stimulated insulin secretion is the common primary defect of these monogenic forms of