Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Human, Rézaei"'
Autor:
Annick Le Dur, Thanh Lan Laï, Marie-George Stinnakre, Aude Laisné, Nathalie Chenais, Sabine Rakotobe, Bruno Passet, Fabienne Reine, Solange Soulier, Laetitia Herzog, Gaëlle Tilly, Human Rézaei, Vincent Béringue, Jean-Luc Vilotte, Hubert Laude
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
PrPC protein plays a key role in prion transmission across species. Here, the authors compare transmission of a representative scrapie isolate to transgenic mice expressing variable levels of the same Prnp allele as the donor sheep, and find divergen
Externí odkaz:
https://doaj.org/article/010dfaabcfa2495381f0b8a4b4e912ee
Autor:
Annick, Le Dur, Thanh Lan, Laï, Marie-George, Stinnakre, Aude, Laisné, Nathalie, Chenais, Sabine, Rakotobe, Bruno, Passet, Fabienne, Reine, Solange, Soulier, Laetitia, Herzog, Gaëlle, Tilly, Human, Rézaei, Vincent, Béringue, Jean-Luc, Vilotte, Hubert, Laude
Publikováno v:
Nature Communications
Prions induce a fatal neurodegenerative disease in infected host brain based on the refolding and aggregation of the host-encoded prion protein PrPC into PrPSc. Structurally distinct PrPSc conformers can give rise to multiple prion strains. Constrain