Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Huma Mohsin"'
Autor:
Fang Jia, Carolyn J. Anderson, Jiuli Zhang, Carolyn J. Henry, Huma Mohsin, Jeffrey N. Bryan, Nellie K. Owen, Michael R. Lewis, Geethapriya Sivaguru
Publikováno v:
Veterinary and Comparative Oncology. 2:82-90
Copper-64 emits beta(+) and beta(-) particles suitable for positron emission tomography and radioimmunotherapy (RIT) of cancer. Copper-64-labelled antibodies have caused complete responses in laboratory animal RIT studies at far lower radiation doses
Autor:
Jim Simon, Silvia S. Jurisson, William H. Miller, Don B. Axworthy, Michael R. Lewis, Alan R. Ketring, Geethapriya Sivaguru, Huma Mohsin, R. Keith Frank, Jeffrey N. Bryan, Louis J. Theodore, Cathy S. Cutler, Fang Jia
Publikováno v:
Bioconjugate chemistry. 22(12)
The therapeutic efficacies of radiolabeled biotin, pretargeted by monoclonal antibody (mAb)-streptavidin fusion protein CC49 scFvSA, were compared to those of radiolabeled mAb CC49, using the three radiolanthanides in an animal model of human colon c
Autor:
William H. Miller, Huma Mohsin, Michael R. Lewis, Carolyn J. Henry, Geethapriya Sivaguru, Fang Jia, Carolyn J. Anderson, Jeffrey N. Bryan
We previously described a two-antibody model of (64)Cu radioimmunotherapy to evaluate low-dose, solid-tumor response. This model was designed to test the hypothesis that cellular internalization is critical in causing tumor cell death by mechanisms i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7d8084e8cf32074998a6f629849af92
https://europepmc.org/articles/PMC3142363/
https://europepmc.org/articles/PMC3142363/
Autor:
Cathy S. Cutler, Tiffani Shelton, Gyongyi Gulyas, Jaime Simon, R. Keith Frank, Michael R. Lewis, Timothy J. Hoffman, Jonathan M. Fitzsimmons, Garry E. Kiefer, Phillip S. Athey, Silvia S. Jurisson, Huma Mohsin, Susan Z. Lever
Publikováno v:
Nuclear medicine and biology. 34(5)
Three 1,4,7,10-tetraazacyclododecane-N,N',N",N"'-tetraacetic acid (DOTA) analogues were evaluated for relative in vivo stability when radiolabeled with (111)In, (90)Y and (177)Lu and conjugated to the monoclonal antibody B72.3. The DOTA analogues eva
Autor:
Silvia S. Jurisson, Fang Jia, Jaime Simon, Huma Mohsin, Michael J. Hudson, Timothy J. Hoffman, Alan R. Ketring, Geethapriya Sivaguru, Phillip S. Athey, Tiffani D. Shelton, Michael R. Lewis, Cathy S. Cutler, R. Keith Frank
Publikováno v:
Bioconjugate chemistry. 17(2)
The radiolanthanides 149Pm, 166Ho, and 177Lu have decay characteristics suitable for radioimmunotherapy (RIT) of cancer. N-Hydroxysulfosuccinimidyl DOTA (DOTA-OSSu) and methoxy-DOTA (MeO-DOTA) were conjugated to the anti-TAG-72 monoclonal antibody CC
Autor:
Huma Mohsin, Fang Jia, Michael R. Lewis, Carolyn J. Anderson, William H. Miller, Jeffrey N. Bryan, Clay B. Siegall, Carolyn J. Henry
Publikováno v:
Veterinary and Comparative Oncology. 2:99-99
Objectives: We previously presented preliminary data on pilot biodistributions of 64Cu-labeled monoclonal antibodies (mAbs).1 The purpose of the present studies was to obtain comprehensive biodistributions using a two-antibody model for direct compar
Autor:
Huma Mohsin, Fang Jia, JeffreyN. Bryan, Geethapriya Sivaguru, Cathy S. Cutler, Alan R. Ketring, WilliamH. Miller, Jim Simón, R. Keith Frank, Louis J. Theodore, Don B. Axworthy, Silvia S. Jurisson, Michael R. Lewis
Publikováno v:
Bioconjugate Chemistry; Dec2011, Vol. 22 Issue 12, p2444-2452, 9p