Virus-encoded G-protein-coupled receptors:constitutively active (dys)regulators of cell function and their potential as drug target

Autor: Vischer, H F, Hulshof, J W, de Esch, I J P, Smit, M J, Leurs, R

Publikováno v: Vischer, H F, Hulshof, J W, de Esch, I J P, Smit, M J & Leurs, R 2006, ' Virus-encoded G-protein-coupled receptors : constitutively active (dys)regulators of cell function and their potential as drug target ', Ernst Schering Foundation Symposium Proceedings, no. 2, pp. 187-209 .

G-protein-coupled receptors encoded by herpesviruses such as EBV, HCMV and KSHV are very interesting illustrations of the (patho)physiological importance of constitutive GPCR activity. These viral proteins are expressed on the cell surface of infecte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______4612::9a6dd05e80ffc92887dba599ad921eb2
https://hdl.handle.net/1871.1/095289e9-a4fa-467f-8578-19dc2259b175

Synthesis and Structure−Activity Relationship of the First Nonpeptidergic Inverse Agonists for the Human Cytomegalovirus Encoded Chemokine Receptor US28

Autor: Hulshof, J. W., Casarosa, P., Menge, W. M. P. B., Kuusisto, L. M. S., Goot, H. van der, Smit, M. J., Esch, I. J. P. de, Leurs, R.

Publikováno v: Journal of Medicinal Chemistry; October 2005, Vol. 48 Issue: 20 p6461-6471, 11p

Virus-encoded G-protein-coupled receptors: constitutively active (dys)regulators of cell function and their potential as drug target

Autor: Vischer, H. F., Hulshof, J. W., I.J.P. de Esch, Smit, M. J., Leurs, R.

Publikováno v: Vrije Universiteit Amsterdam
Ernst Schering Foundation Symposium Proceedings, 187-209. Springer Verlag
ISSUE=2;STARTPAGE=187;ENDPAGE=209;ISSN=1866-9425;TITLE=Ernst Schering Foundation Symposium Proceedings
Vischer, H F, Hulshof, J W, de Esch, I J P, Smit, M J & Leurs, R 2006, ' Virus-encoded G-protein-coupled receptors: constitutively active (dys)regulators of cell function and their potential as drug target ', Ernst Schering Foundation Symposium Proceedings, no. 2, pp. 187-209 .

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::0d9770666dc42486b841156fea4411d6
https://research.vu.nl/en/publications/c222b387-3fac-476d-a3f7-948184ebbf62

New synthetic flavonoids as potent protectors against doxorubicin-induced cardiotoxicity.

Autor: van Acker FA; Department of Medical Oncology, University Hospital Vrije Universiteit, Amsterdam, The Netherlands. f.vanacker@azvu.nl, Hulshof JW, Haenen GR, Menge WM, van der Vijgh WJ, Bast A

Publikováno v: Free radical biology & medicine [Free Radic Biol Med] 2001 Jul 01; Vol. 31 (1), pp. 31-7.