Zobrazeno 1 - 10
of 4 311
pro vyhledávání: '"Hulme, P"'
Autor:
K. A. Stark, G. Rinaldi, A. Costain, S. Clare, C. Tolley, A. Almeida, C. McCarthy, K. Harcourt, C. Brandt, T. D. Lawley, M. Berriman, A. S. MacDonald, J. E. Forde-Thomas, B. J. Hulme, K. F. Hoffmann, C. Cantacessi, A. Cortés
Publikováno v:
Animal Microbiome, Vol 6, Iss 1, Pp 1-19 (2024)
Abstract Mounting evidence of the occurrence of direct and indirect interactions between the human blood fluke, Schistosoma mansoni, and the gut microbiota of rodent models raises questions on the potential role(s) of the latter in the pathophysiolog
Externí odkaz:
https://doaj.org/article/00b9a9d991ae49ddba6d0fd576bc8ed2
Publikováno v:
Health and Quality of Life Outcomes, Vol 22, Iss 1, Pp 1-8 (2024)
Abstract Background Approximately 1.5 million adults in the UK have a learning disability. The difference between age at death for this group and the general population is 26 years for females and 22 years for males. The NHS Long Term Plan (January 2
Externí odkaz:
https://doaj.org/article/0bade497eda64c0ba88507cfb8bf5226
Autor:
Thomas Hartwig Siebner, Jens Dahlgaard Hove, Christopher Fugl Madelung, Oliver James Hulme, Flemming Bendtsen, Hartwig Roman Siebner, Mads Barløse
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract We recently used phase-contrast magnetic resonance imaging (PC-MRI) to demonstrate an attenuated postprandial blood flow response in the superior mesenteric artery (SMA) in patients with Parkinson's disease compared to age- and sex-matched h
Externí odkaz:
https://doaj.org/article/a3c06e14d4d44837a153b6c5c2b3b5e4
Autor:
Kenneth F. Baker, David McDonald, Gillian Hulme, Rafiqul Hussain, Jonathan Coxhead, David Swan, Axel R. Schulz, Henrik E. Mei, Lucy MacDonald, Arthur G. Pratt, Andrew Filby, Amy E. Anderson, John D. Isaacs
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Immune-mediated inflammatory diseases (IMIDs) are typically characterised by relapsing and remitting flares of inflammation. However, the unpredictability of disease flares impedes their study. Addressing this critical knowledge gap, we use
Externí odkaz:
https://doaj.org/article/34a7ab6817b24901ae14c64e18ae1869
Publikováno v:
BMC Oral Health, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background Urgent dental care may be the only place where many people, especially vulnerable groups, access care. This presents an opportunity for delivery of a behavioural intervention promoting planned dental visiting, which may help addre
Externí odkaz:
https://doaj.org/article/ce7e7466d9b246cc9f98faf8c673dbec
Real-time forecasting of disease outbreaks requires standardized outputs generated in a timely manner. Development of pipelines to automate infectious disease forecasts can ensure that parameterization and software dependencies are common to any exec
Externí odkaz:
http://arxiv.org/abs/2208.05019
Autor:
Andrew Steptoe, John Macleod, Daniel McCartney, Aziz Sheikh, Annie Herbert, Ben Goldacre, David Evans, Louise Jones, Sam Harper, Michael Green, Nicholas Timpson, John Wright, Liam Smeeth, Laurie A Tomlinson, Sinead Brophy, Kate Tilling, Andy Gibson, Paola Zaninotto, Stefan Neubauer, Yinghui Wei, Betty Raman, Chloe Park, Alun Hughes, Jonathan Sterne, Elena Lukaschuk, Stefan Piechnik, Angela Wood, Mark Green, Agnieszka Lemanska, Krishnan Bhaskaran, Kathryn Willan, Elsie Horne, Hannah Woodward, Ian Douglas, Andrew Wong, Andy Boyd, Harriet Forbes, Sinéad Langan, Nishi Chaturvedi, Tom Palmer, Kathryn Mansfield, Rachel Denholm, Emily Herrett, Kevin Wang, Bo Hou, Felix Greaves, Laura Sheard, Praveetha Patalay, Kishan Patel, Jessica Morley, Bang Zheng, Charlotte Booth, Spiros Denaxas, Brian MacKenna, Ruth E Costello, Jonathan Kennedy, William Hulme, Michael Parker, Geneviève Cezard, Syed A Shah, Amir Mehrkar, Peter Inglesby, Jonathan Cockburn, Laurie Tomlinson, John Parry, Frank Hester, Eoin McElroy, Amelia Green, Gillian Santorelli, Alisia Carnemolla, Richard Shaw, Samantha Ip, Venexia Walker, Emma L Turner, Richard Thomas, Rebecca Rhead, Archie Campbell, Ellen Thompson, Ruth Bowyer, Jane Maddock, Helen Curtis, Alex Walker, Olivia Hamilton, Rosie McEachan, Ellena Badrick, Stephen Smith, Richard Dobson, Stela McLachlan, Vanessa Ferreira, Vittal Katikireddi, Scott Walker, Lucy Teece, Simon Davy, John Tazare, Bettina Moltrecht, Theocharis Kromydas, Giorgio Di Gessa, Gareth Griffith, Viyaasan Mahalingasivam, Elizabeth Tunnicliffe, George Hickman, Tom Ward, Rebecca M Smith, Sam Parsons, Callum Stewart, Amos Folarin, Daniel Kopasker, Claire Steves, Louis Fisher, Sebastian C J Bacon, Lisa Hopcroft, Robin Y Park, Jon Massey, Iain Dillingham, Steven Maude, Wels Jacques, Linda Nab, Christopher Bates, Milan Wiedemann, Ruth Mitchell, Chao Fang, Fatima Almaghrabi, Jingmin Zhu, Lucy Bridges, Kurt Taylor, Colm Andrews, Jean Stafford, Nathan Cheetham, Sebastian CJ Bacon, Alicja Rapala, Robin Flaig, Andrea L Schaffer, Benjamin FC Butler-Cole, Liam Hart Ben Goldacre, Thomas O’Dwyer, Dylan Williams, Anika Knueppel, Katharine M Evans, Samantha Berman, Matthew Crane, Rebecca Whitehorn, Jacqui Oakley, Diane Foster, Kirsteen C Campbell, Alex Kwong, Ana Goncalves Soares, Renin Toms, Lizzie Huntley, Laura Fox, Rochelle Knight, Northstone Kate, Kanagaratnam Arun, Teri North, Marwa AL Arab, Jose IC Coronado, Arun S Karthikeyan, Ploubidis George, Bozena Wielgoszewska, Charis Bridger-Staatz, Paz Garcia, Maxim Freydin, Amy Roberts, Alex Walker Ben Goldacre, Jess Morley, Anoop Shah Richard Silverwood, Thomas Cowling, Kate Mansfield, Tiffany Yang, Tom Bolton, Alexia Sampri, Elena Rafeti, Robert Willans, Fiona Glen, Steve Sharp, Lee Hamill Howes, Lidia Nigrelli, Fintan McArdle, Chelsea Beckford, Yatharth Ranjan, Jd Carpentieri, Sarah Baz, John Kellas, Laura C Saunders, James M Wild, Peter Jezzard, Zeena-Britt Sanders, Lucy Finnigan, Milla Kibble, Francisco Perez-Reche, Dominik Piehlmaier, Edward Parker
Publikováno v:
BMJ Open, Vol 14, Iss 7 (2024)
Objectives Long-term sickness absence from employment has negative consequences for the economy and can lead to widened health inequalities. Sick notes (also called ‘fit notes’) are issued by general practitioners when a person cannot work for he
Externí odkaz:
https://doaj.org/article/1038a096d89044e5a8996a5c8992b394
Autor:
Cecilie F. Rustad, Paul Hoff Backe, Chunsheng Jin, Else Merckoll, Kristian Tveten, Marissa Lucy Maciej‐Hulme, Niclas Karlsson, Trine Prescott, Elise Sandås Sand, Berit Woldseth, Katja Benedikte Prestø Elgstøen, Øystein L. Holla
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 12, Iss 6, Pp n/a-n/a (2024)
Abstract Background Serine residues in the protein backbone of heavily glycosylated proteoglycans are bound to glycosaminoglycans through a tetrasaccharide linker. UXS1 encodes UDP‐glucuronate decarboxylase 1, which catalyzes synthesis of UDP‐xyl
Externí odkaz:
https://doaj.org/article/dc7662c3d97b439ab41d265a01d9ab8e
Autor:
Simon Maksour, Neville Ng, Amy J. Hulme, Sara Miellet, Martin Engel, Sonia Sanz Muñoz, Rachelle Balez, Ben Rollo, Rocio K. Finol-Urdaneta, Lezanne Ooi, Mirella Dottori
Publikováno v:
Heliyon, Vol 10, Iss 12, Pp e32680- (2024)
Repressor element-1 silencing transcription factor (REST) is a transcriptional repressor involved in neurodevelopment and neuroprotection. REST forms a complex with the REST corepressors, CoREST1, CoREST2, or CoREST3 (encoded by RCOR1, RCOR2, and RCO
Externí odkaz:
https://doaj.org/article/2ccd3caa1e844c4b86d0e4c2a10532f7
Autor:
Alasdair D. Henderson, Ben FC. Butler-Cole, John Tazare, Laurie A. Tomlinson, Michael Marks, Mark Jit, Andrew Briggs, Liang-Yu Lin, Oliver Carlile, Chris Bates, John Parry, Sebastian CJ. Bacon, Iain Dillingham, William A. Dennison, Ruth E. Costello, Yinghui Wei, Alex J. Walker, William Hulme, Ben Goldacre, Amir Mehrkar, Brian MacKenna, Emily Herrett, Rosalind M. Eggo, Alex Walker, Amelia Green, Andrea Schaffer, Andrew Brown, Ben Butler-Cole, Caroline Morton, Caroline Walters, Catherine Stables, Christine Cunningham, Christopher Wood, Colm Andrews, David Evans, George Hickman, Helen Curtis, Henry Drysdale, Jessica Morley, Jon Massey, Linda Nab, Lisa Hopcroft, Louis Fisher, Lucy Bridges, Milan Wiedemann, Nicholas DeVito, Orla Macdonald, Peter Inglesby, Rebecca Smith, Richard Croker, Robin Park, Rose Higgins, Sebastian Bacon, Simon Davy, Steven Maude, Thomas O'Dwyer, Tom Ward, Victoria Speed, Liam Hart, Pete Stokes, Krishnan Bhaskaran, Ruth Costello, Thomas Cowling, Ian Douglas, Rosalind Eggo, Stephen Evans, Harriet Forbes, Richard Grieve, Daniel Grint, Sinead Langan, Viyaasan Mahalingasivam, Kathryn Mansfield, Rohini Mathur, Helen McDonald, Edward Parker, Christopher Rentsch, Anna Schultze, Liam Smeeth, Laurie Tomlinson, Jemma Walker, Elizabeth Williamson, Kevin Wing, Angel Wong, Bang Zheng, Christopher Bates, Jonathan Cockburn, Frank Hester, Sam Harper, Shaun O'Hanlon, Alex Eavis, Richard Jarvis, Dima Avramov, Paul Griffiths, Aaron Fowles, Nasreen Parkes, Rafael Perera, David Harrison, Kamlesh Khunti, Jonathan Sterne, Jennifer Quint
Publikováno v:
EClinicalMedicine, Vol 72, Iss , Pp 102638- (2024)
Summary: Background: Long COVID is the patient-coined term for the persistent symptoms of COVID-19 illness for weeks, months or years following the acute infection. There is a large burden of long COVID globally from self-reported data, but the epide
Externí odkaz:
https://doaj.org/article/44f9e56ee26a435d9956ffa4a1354eaa