Mass spectrometry imaging to investigate host-microbe interactions

Autor: Hulme, Heather E.

Mass spectrometry imaging (MSI) is a powerful tool for mapping the spatial distribution and relative abundance of molecules across a sample surface. The distribution of proteins, metabolites, lipids and drugs can be determined and unlike other molecu

Externí odkaz: https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.739271

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Monocytes mediate Salmonella Typhimurium-induced tumor growth inhibition in a mouse melanoma model

Autor: Johnson, Síle A., Ormsby, Michael J., Wessel, Hannah, Hulme, Heather, Bravo-Blas, Alberto, McIntosh, Anne, Mason, Susan, Coffelt, Seth, Tait, Stephen W.G., Mcl. Mowat, Allan, Milling, Simon, Blyth, Karen, Wall, Daniel M.

The use of bacteria as an alternative cancer therapy has been reinvestigated in recent years. SL7207: an auxotrophic Salmonella enterica serovar Typhimurium aroA mutant with immune-stimulatory potential has proven a promising strain for this purpose.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::0bbf896193adfe48becf2e20731e2663
http://dspace.stir.ac.uk/bitstream/1893/33640/1/Johnson-etal-EJI-2021.pdf

Simultaneous mass spectrometry imaging of multiple neuropeptides in the brain and alterations induced by experimental parkinsonism and L-DOPA therapy

Autor: Hulme, Heather, Fridjonsdottir, Elva, Gunnarsdottir, Halla, Vallianatou, Theodosia, Zhang, Xiaoqun, Wadensten, Henrik, Shariatgorji, Mohammadreza, Nilsson, Anna, Bezard, Erwan, Svenningsson, Per, Andrén, Per E.

Publikováno v: Neurobiology of Disease
Neurobiology of Disease, Elsevier, 2020, 137, pp.104738. ⟨10.1016/j.nbd.2020.104738⟩
Neurobiology of Disease, Vol 137, Iss, Pp 104738-(2020)

Neuropeptides are important signalling molecules in the brain and alterations in their expression levels have been linked to neurological disorders such as Parkinson's disease. It is challenging to map neuropeptide changes across and within brain reg

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::4c7569c01ac47468fcc7748b1554c1dc
https://hal.archives-ouvertes.fr/hal-02492688