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Akademický článek

TRPM7 in neurodevelopment and therapeutic prospects for neurodegenerative disease.

Autor: Luo Z; Department of Physiology, Temerty Faculty of Medicine, University of Toronto, 1 King's College Circle, Toronto, Ontario, M5S 1A8, Canada; Department of Surgery, Temerty Faculty of Medicine, University of Toronto, 1 King's College Circle, Toronto, Ontario, M5S 1A8, Canada., Zhang X; Department of Physiology, Temerty Faculty of Medicine, University of Toronto, 1 King's College Circle, Toronto, Ontario, M5S 1A8, Canada; Department of Surgery, Temerty Faculty of Medicine, University of Toronto, 1 King's College Circle, Toronto, Ontario, M5S 1A8, Canada., Fleig A; Center for Biomedical Research at The Queen's Medical Center and John A. Burns School of Medicine and Cancer Center at the University of Hawaii, Honolulu, HI, 96720, USA., Romo D; Department of Chemistry & Biochemistry, Baylor University, Waco, TX 76798-7348, USA; The CPRIT Synthesis and Drug-Lead Discovery Laboratory, Baylor University, Waco, TX 76798, USA., Hull KG; Department of Chemistry & Biochemistry, Baylor University, Waco, TX 76798-7348, USA., Horgen FD; Department of Natural Sciences, Hawaii Pacific University, Kaneohe, HI, 96744, USA., Sun HS; Department of Physiology, Temerty Faculty of Medicine, University of Toronto, 1 King's College Circle, Toronto, Ontario, M5S 1A8, Canada; Department of Surgery, Temerty Faculty of Medicine, University of Toronto, 1 King's College Circle, Toronto, Ontario, M5S 1A8, Canada; Department of Pharmacology, Temerty Faculty of Medicine, University of Toronto, 1 King's College Circle, Toronto, Ontario, M5S 1A8, Canada; Leslie Dan Faculty of Pharmacy, University of Toronto, 144 College Street, Toronto, Ontario, M5S 3M2, Canada. Electronic address: hss.sun@utoronto.ca., Feng ZP; Department of Physiology, Temerty Faculty of Medicine, University of Toronto, 1 King's College Circle, Toronto, Ontario, M5S 1A8, Canada. Electronic address: zp.feng@utoronto.ca.

Publikováno v: Cell calcium [Cell Calcium] 2024 Jun; Vol. 120, pp. 102886. Date of Electronic Publication: 2024 Apr 06.

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Akademický článek

Dopamine-Derived Guanidine Alkaloids from a Didemnidae Tunicate: Isolation, Synthesis, and Biological Activities.

Autor: Sakai R; Faculty and Graduate School of Fisheries Sciences, Hokkaido University, 3-1-1 Minato-Cho, Hakodate, Hokkaido 041-8611, Japan., Matsumura K; Graduate School of Fisheries Sciences, Hokkaido University, 3-1-1 Minato-Cho, Hakodate, Hokkaido 041-8611, Japan., Uchimasu H; Graduate School of Fisheries Sciences, Hokkaido University, 3-1-1 Minato-Cho, Hakodate, Hokkaido 041-8611, Japan., Miyako K; Graduate School of Fisheries Sciences, Hokkaido University, 3-1-1 Minato-Cho, Hakodate, Hokkaido 041-8611, Japan., Taniguchi T; Frontier Research Center for Advanced Material and Life Science, Faculty of Advanced Life Science, Hokkaido University, Kita 21 Nishi 11, Sapporo 001-0021, Japan., Kovvuri VRR; Department of Chemistry and Biochemistry & The Baylor Synthesis and Drug Lead Discovery Laboratory, Baylor University, 101 Bagby Avenue, Waco, Texas 76798-7348, United States., Acharige AD; Department of Chemistry and Biochemistry & The Baylor Synthesis and Drug Lead Discovery Laboratory, Baylor University, 101 Bagby Avenue, Waco, Texas 76798-7348, United States., Hull KG; Department of Chemistry and Biochemistry & The Baylor Synthesis and Drug Lead Discovery Laboratory, Baylor University, 101 Bagby Avenue, Waco, Texas 76798-7348, United States., Romo D; Department of Chemistry and Biochemistry & The Baylor Synthesis and Drug Lead Discovery Laboratory, Baylor University, 101 Bagby Avenue, Waco, Texas 76798-7348, United States., Thaveepornkul L; Institute of Molecular Biosciences, Mahidol University, 25/25 Phutthamonthon 4 Road, Salaya, Nakhon Pathom 73170, Thailand., Chimnaronk S; Institute of Molecular Biosciences, Mahidol University, 25/25 Phutthamonthon 4 Road, Salaya, Nakhon Pathom 73170, Thailand., Miyamoto H; Division of Global Epidemiology, International Institute for Zoonosis Control, Hokkaido University, Kita 20 Nishi 10, Sapporo 001-0020, Japan., Takada A; Division of Global Epidemiology, International Institute for Zoonosis Control, Hokkaido University, Kita 20 Nishi 10, Sapporo 001-0020, Japan.; International Collaboration Unit, International Institute for Zoonosis Control, Hokkaido University, Kita 20 Nishi 10, Sapporo 001-0020, Japan.; One Health Research Center, Hokkaido University, Kita 20 Nishi 10, Sapporo 001-0020, Japan., Watari H; Faculty and Graduate School of Fisheries Sciences, Hokkaido University, 3-1-1 Minato-Cho, Hakodate, Hokkaido 041-8611, Japan., Fujita MJ; Faculty and Graduate School of Fisheries Sciences, Hokkaido University, 3-1-1 Minato-Cho, Hakodate, Hokkaido 041-8611, Japan., Sakaue J; Southern Marine Laboratory, P.O. Box 6096, Koror 96940, Palau.

Publikováno v: The Journal of organic chemistry [J Org Chem] 2024 May 03; Vol. 89 (9), pp. 5977-5987. Date of Electronic Publication: 2024 Apr 01.

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Akademický článek

Transient Receptor Potential Melastatin 7 (TRPM7) Ion Channel Inhibitors: Preliminary SAR and Conformational Studies of Xenicane Diterpenoids from the Hawaiian Soft Coral Sarcothelia edmondsoni .

Autor: Yao G; Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, People's Republic of China.; Chemistry and Biochemistry, Hawaii Pacific University, Kaneohe, Hawaii 96744, United States., Parris MR; Department of Chemistry & Biochemistry, Baylor University, Waco, Texas 76798-7348, United States., Kuo WC; Chemistry and Biochemistry, Hawaii Pacific University, Kaneohe, Hawaii 96744, United States., Pörzgen P; Chemistry and Biochemistry, Hawaii Pacific University, Kaneohe, Hawaii 96744, United States., Castillo B; Chemistry and Biochemistry, Hawaii Pacific University, Kaneohe, Hawaii 96744, United States., Mason ES; Department of Chemistry & Biochemistry, Baylor University, Waco, Texas 76798-7348, United States., Chinchilla A; Department of Chemistry & Biochemistry, Baylor University, Waco, Texas 76798-7348, United States., Huang J; Laboratory of Cell and Molecular Signaling, Center for Biomedical Research at The Queen's Medical Center, Honolulu, Hawaii 96813, United States., Suzuki S; Laboratory of Cell and Molecular Signaling, Center for Biomedical Research at The Queen's Medical Center, Honolulu, Hawaii 96813, United States., Ross R; Chemistry and Biochemistry, Hawaii Pacific University, Kaneohe, Hawaii 96744, United States., Akana E; Chemistry and Biochemistry, Hawaii Pacific University, Kaneohe, Hawaii 96744, United States., Vander Schuit S; Chemistry and Biochemistry, Hawaii Pacific University, Kaneohe, Hawaii 96744, United States., Miller SP; Department of Pediatrics, University of British Columbia and BC Children's Hospital, Vancouver, British Columbia V6H 3N1, Canada., Penner R; Laboratory of Cell and Molecular Signaling, Center for Biomedical Research at The Queen's Medical Center, Honolulu, Hawaii 96813, United States., Sun HS, Feng ZP, Hull KG; Department of Chemistry & Biochemistry, Baylor University, Waco, Texas 76798-7348, United States.; The Baylor Synthesis and Drug-Lead Discovery Laboratory, Baylor University, Waco, Texas 76798, United States., Romo D; Department of Chemistry & Biochemistry, Baylor University, Waco, Texas 76798-7348, United States., Fleig A; Laboratory of Cell and Molecular Signaling, Center for Biomedical Research at The Queen's Medical Center, Honolulu, Hawaii 96813, United States., Horgen FD; Chemistry and Biochemistry, Hawaii Pacific University, Kaneohe, Hawaii 96744, United States.

Publikováno v: Journal of natural products [J Nat Prod] 2024 Apr 26; Vol. 87 (4), pp. 783-797. Date of Electronic Publication: 2024 Mar 27.

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Akademický článek

Second-Shell Amino Acid R266 Helps Determine N -Succinylamino Acid Racemase Reaction Specificity in Promiscuous N -Succinylamino Acid Racemase/ o -Succinylbenzoate Synthase Enzymes.

Autor: Truong DP; Department of Biochemistry and Biophysics, Texas A&M University, 2128 TAMU, College Station, Texas 77843-2128, United States., Rousseau S; Department of Biochemistry and Biophysics, Texas A&M University, 2128 TAMU, College Station, Texas 77843-2128, United States., Machala BW; Department of Biochemistry and Biophysics, Texas A&M University, 2128 TAMU, College Station, Texas 77843-2128, United States., Huddleston JP; Department of Chemistry, Texas A&M University, 3255 TAMU, College Station, Texas 77843-3255, United States., Zhu M; Baylor Synthesis and Drug-Lead Discovery Laboratory, Department of Chemistry and Biochemistry, Baylor University, One Bear Place, Waco, Texas 76798-7348, United States., Hull KG; Baylor Synthesis and Drug-Lead Discovery Laboratory, Department of Chemistry and Biochemistry, Baylor University, One Bear Place, Waco, Texas 76798-7348, United States., Romo D; Baylor Synthesis and Drug-Lead Discovery Laboratory, Department of Chemistry and Biochemistry, Baylor University, One Bear Place, Waco, Texas 76798-7348, United States., Raushel FM; Department of Biochemistry and Biophysics, Texas A&M University, 2128 TAMU, College Station, Texas 77843-2128, United States.; Department of Chemistry, Texas A&M University, 3255 TAMU, College Station, Texas 77843-3255, United States., Sacchettini JC; Department of Chemistry, Texas A&M University, 3255 TAMU, College Station, Texas 77843-3255, United States., Glasner ME; Department of Biochemistry and Biophysics, Texas A&M University, 2128 TAMU, College Station, Texas 77843-2128, United States.

Publikováno v: Biochemistry [Biochemistry] 2021 Dec 21; Vol. 60 (50), pp. 3829-3840. Date of Electronic Publication: 2021 Nov 30.

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Akademický článek

Necator americanus Ancylostoma Secreted Protein-2 ( Na -ASP-2) Binds an Ascaroside (ascr#3) in Its Fatty Acid Binding Site.

Autor: El Atab O; Division of Biochemistry, Department of Biology, University of Fribourg, Fribourg, Switzerland., Darwiche R; Division of Biochemistry, Department of Biology, University of Fribourg, Fribourg, Switzerland.; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, United States., Truax NJ; Department of Chemistry and Biochemistry & The CPRIT Synthesis and Drug-Lead Discovery Laboratory, Baylor University, Waco, TX, United States., Schneiter R; Division of Biochemistry, Department of Biology, University of Fribourg, Fribourg, Switzerland., Hull KG; Department of Chemistry and Biochemistry & The CPRIT Synthesis and Drug-Lead Discovery Laboratory, Baylor University, Waco, TX, United States., Romo D; Department of Chemistry and Biochemistry & The CPRIT Synthesis and Drug-Lead Discovery Laboratory, Baylor University, Waco, TX, United States., Asojo OA; Department of Chemistry and Biochemistry, Hampton University, Hampton, VA, United States.; National School of Tropical Medicine, Baylor College of Medicine, Houston, TX, United States.

Publikováno v: Frontiers in chemistry [Front Chem] 2020 Dec 17; Vol. 8, pp. 608296. Date of Electronic Publication: 2020 Dec 17 (Print Publication: 2020).

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