The COLO-COHORT (Colorectal Cancer Cohort) study: Protocol for a multi-centre, observational research study and development of a consent-for-contact research platform

Autor: Hampton, JS, Koo, S, Dobson, C, Stewart, CJ, Neilson, LJ, Montague, K, Mitra, S, Whelpton, J, Addison, C, Kelly, P, Rushton, S, Hull, MA, Sharp, L, Rees, CJ

Aim The COLO-COHORT study aims to produce a multi-factorial risk prediction model for colorectal neoplasia that can be used to target colonoscopy to those at greatest risk of colorectal neoplasia, ensuring that people are not investigated unnecessari

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::24f2076bb2188173c77cdf15914e50cd

Paracrine cyclooxygenase-2 activity by macrophages drives colorectal adenoma progression in the Apc Min/+ mouse model of intestinal tumorigenesis

Autor: Hull, MA, Cuthbert, RJ, Ko, CWS, Scott, DJ, Cartwright, EJ, Hawcroft, G, Perry, SL, Ingram, N, Carr, IM, Markham, AF, Bonifer, C, Coletta, PL

Publikováno v: Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Scientific Reports

Genetic deletion or pharmacological inhibition of cyclooxygenase (COX)-2 abrogates intestinal adenoma development at early stages of colorectal carcinogenesis. COX-2 is localised to stromal cells (predominantly macrophages) in human and mouse intesti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::630891d6f7325a079f53e7acaa060f06
https://doaj.org/article/e481426f4bf8467fae7994ac44635d17

Obesity surgery and risk of colorectal and other obesity-related cancers: An English population-based cohort study

Autor: Aravani, A, Downing, A, Thomas, JD, Lagergren, J, Morris, EJA, Hull, MA

Publikováno v: Aravani, A, Downing, A, Thomas, J D, Lagergren, J, Morris, E J A & Hull, M A 2018, ' Obesity surgery and risk of colorectal and other obesity-related cancers : An English population-based cohort study ', Cancer Epidemiology, vol. 53, pp. 99-104 . https://doi.org/10.1016/j.canep.2018.01.002

Background The association between obesity surgery (OS) and cancer risk remains unclear. We investigated this association across the English National Health Service. A population-based Swedish study has previously suggested that OS may increase the r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::c76753324e3850e3e511b717b8adca75
https://eprints.whiterose.ac.uk/126255/8/1-s2.0-S187778211830002X-main.pdf

Measurement of red blood cell eicosapentaenoic acid (EPA) levels in a randomised trial of EPA in patients with colorectal cancer liver metastases

Autor: Watson, H, Cockbain, AJ, Spencer, J, Race, A, Volpato, M, Loadman, PM, Toogood, GJ, Hull, MA

We investigated red blood cell (RBC) PUFA profiles, and the predictive value of RBC EPA content for tumour EPA exposure and clinical outcomes, in the EMT study, a randomised trial of EPA in patients awaiting colorectal cancer (CRC) liver metastasis s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::f4cdce8e6fcba08a3736a46820585bb5

Eicosapentaenoic Acid-Free Fatty Acid Strongly Prevents and Suppresses Colonic Tumors in Colitis-Associated Colorectal Cancer

Autor: Piazzi G, D'Argenio G, Mazzone G, Prossomariti A, Munarini A, Ceccarelli C, Fazio C, D'Angelo L, Belluzzi A, Chieco P, Hull MA, Romano M, Bazzoli F, Ricciardiello L., Lembo, Vincenzo, VITAGLIONE, PAOLA, FOGLIANO, VINCENZO

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3730::62b55d5b3d777554406e1d41d42ea35d
http://hdl.handle.net/11588/597111