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The lipopeptide Pam3CSK4 inhibits Rift Valley fever virus infection and protects from encephalitis.

Autor: Griesman T; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia Pennsylvania, United States of America., McMillen CM; Center for Vaccine Research, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.; Department of Infectious Diseases and Microbiology, University of Pittsburgh School of Public Health, Pittsburgh, Pennsylvania, United States of America., Negatu SG; Department of Microbiology, University of Pennsylvania, Philadelphia Pennsylvania, Unites States of America., Hulahan JJ; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia Pennsylvania, United States of America., Whig K; High throughput screening core, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America., Dohnalová L; Department of Microbiology, University of Pennsylvania, Philadelphia Pennsylvania, Unites States of America., Dittmar M; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia Pennsylvania, United States of America., Thaiss CA; Department of Microbiology, University of Pennsylvania, Philadelphia Pennsylvania, Unites States of America., Jurado KA; Department of Microbiology, University of Pennsylvania, Philadelphia Pennsylvania, Unites States of America., Schultz DC; High throughput screening core, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America., Hartman AL; Center for Vaccine Research, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.; Department of Infectious Diseases and Microbiology, University of Pittsburgh School of Public Health, Pittsburgh, Pennsylvania, United States of America., Cherry S; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia Pennsylvania, United States of America.; High throughput screening core, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.

Publikováno v: PLoS pathogens [PLoS Pathog] 2024 Jun 27; Vol. 20 (6), pp. e1012343. Date of Electronic Publication: 2024 Jun 27 (Print Publication: 2024).