Rare variants in $\textit{GP1BB}$ are responsible for autosomal dominant macrothrombocytopenia

Autor: Sivapalaratnam, S, Westbury, SK, Stephens, JC, Greene, D, Downes, K, Kelly, AM, Lentaigne, C, Astle, WJ, Huizinga, EG, Nurden, P, Papadia, S, Peerlinck, K, Penkett, CJ, Perry, DJ, Roughley, C, Simeoni, I, Stirrups, K, Hart, DP, Tait, RC, Mumford, AD, NIHR BioResource, Laffan, MA, Freson, K, Ouwehand, WH, Kunishima, S, Turro, E

The von Willebrand receptor complex, which is composed of the glycoproteins Ibα, Ibβ, GPV, and GPIX, plays an essential role in the earliest steps in hemostasis. During the last 4 decades, it has become apparent that loss of function of any 1 of 3

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74ade4819585be90a9b5bcd14b4319f5
https://www.repository.cam.ac.uk/handle/1810/262169

Coronavirus hemagglutinin-esterase and spike proteins coevolve for functional balance and optimal virion avidity.

Autor: Lang Y; Virology Division, Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, 3584 CL Utrecht, The Netherlands., Li W; Virology Division, Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, 3584 CL Utrecht, The Netherlands., Li Z; Department of Chemical Biology and Drug Discovery, Utrecht Institute for Pharmaceutical Sciences, Bijvoet Center for Biomolecular Research, Utrecht University, 3584 CG Utrecht, The Netherlands., Koerhuis D; Virology Division, Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, 3584 CL Utrecht, The Netherlands., van den Burg ACS; Virology Division, Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, 3584 CL Utrecht, The Netherlands., Rozemuller E; GenDx B.V., 3584 CM Utrecht, The Netherlands., Bosch BJ; Virology Division, Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, 3584 CL Utrecht, The Netherlands., van Kuppeveld FJM; Virology Division, Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, 3584 CL Utrecht, The Netherlands., Boons GJ; Department of Chemical Biology and Drug Discovery, Utrecht Institute for Pharmaceutical Sciences, Bijvoet Center for Biomolecular Research, Utrecht University, 3584 CG Utrecht, The Netherlands.; Department of Chemistry, University of Georgia, Athens, GA 30602.; Complex Carbohydrate Research Center, University of Georgia, Athens, GA 30602., Huizinga EG; Crystal and Structural Chemistry, Bijvoet Center for Biomolecular Research, Faculty of Sciences, Utrecht University, 3584 CH Utrecht, The Netherlands., van der Schaar HM; GenDx B.V., 3584 CM Utrecht, The Netherlands., de Groot RJ; Virology Division, Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, 3584 CL Utrecht, The Netherlands; r.j.degroot@uu.nl.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Oct 13; Vol. 117 (41), pp. 25759-25770. Date of Electronic Publication: 2020 Sep 29.

Post COVID-19 persistent symptoms and functional status in COVID-19 survivors: a multi-center study.

Autor: Goda, Amal Mahmoud Ibrahim¹ (AUTHOR), Ahmed, Osama Amin Abd Elhamid² (AUTHOR), Wedn, Ahmed Moustafa Abdel Samad² (AUTHOR), Manzour, Ayat F.¹ (AUTHOR) ayatfaroukm@yahoo.com

Publikováno v: Egyptian Journal of Bronchology. 8/5/2024, Vol. 18 Issue 1, p1-11. 11p.

Human coronaviruses OC43 and HKU1 bind to 9- O -acetylated sialic acids via a conserved receptor-binding site in spike protein domain A.

Autor: Hulswit RJG; Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, 3584 CH Utrecht, The Netherlands., Lang Y; Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, 3584 CH Utrecht, The Netherlands., Bakkers MJG; Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, 3584 CH Utrecht, The Netherlands., Li W; Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, 3584 CH Utrecht, The Netherlands., Li Z; Department of Chemical Biology and Drug Discovery and Bijvoet Center for Biomolecular Research, Utrecht University, 3584 CG Utrecht, The Netherlands., Schouten A; Crystal and Structural Chemistry, Bijvoet Center for Biomolecular Research, Faculty of Sciences, Utrecht University, 3584 CH Utrecht, The Netherlands., Ophorst B; Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, 3584 CH Utrecht, The Netherlands., van Kuppeveld FJM; Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, 3584 CH Utrecht, The Netherlands., Boons GJ; Department of Chemical Biology and Drug Discovery and Bijvoet Center for Biomolecular Research, Utrecht University, 3584 CG Utrecht, The Netherlands.; Department of Chemistry, University of Georgia, Athens, GA 30602.; Complex Carbohydrate Research Center, University of Georgia, Athens, GA 30602., Bosch BJ; Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, 3584 CH Utrecht, The Netherlands., Huizinga EG; Crystal and Structural Chemistry, Bijvoet Center for Biomolecular Research, Faculty of Sciences, Utrecht University, 3584 CH Utrecht, The Netherlands., de Groot RJ; Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, 3584 CH Utrecht, The Netherlands; r.j.degroot@uu.nl.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2019 Feb 12; Vol. 116 (7), pp. 2681-2690. Date of Electronic Publication: 2019 Jan 24.

Molecular basis determining species specificity for TLR2 inhibition by staphylococcal superantigen-like protein 3 (SSL3).

Autor: Koymans KJ; Department of Medical Microbiology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands. k.j.koymans@umcutrecht.nl., Feitsma LJ; Crystal and Structural Chemistry, Department of Chemistry, Faculty of Science, Bijvoet Center for Biomolecular Research, Utrecht University, Utrecht, The Netherlands., Bisschop A; Department of Medical Microbiology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., Huizinga EG; Crystal and Structural Chemistry, Department of Chemistry, Faculty of Science, Bijvoet Center for Biomolecular Research, Utrecht University, Utrecht, The Netherlands., van Strijp JAG; Department of Medical Microbiology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., de Haas CJC; Department of Medical Microbiology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., McCarthy AJ; Department of Medical Microbiology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.

Publikováno v: Veterinary research [Vet Res] 2018 Nov 28; Vol. 49 (1), pp. 115. Date of Electronic Publication: 2018 Nov 28.