Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Huizhi Zhao"'
Autor:
Yongshuai Han, Shihui Wang, Yaomei Wang, Yumin Huang, Chengjie Gao, Xinhua Guo, Lixiang Chen, Huizhi Zhao, Xiuli An
Publikováno v:
Genomics, Proteomics & Bioinformatics, Vol 21, Iss 6, Pp 1117-1132 (2023)
The fetal liver (FL) is the key erythropoietic organ during fetal development, but knowledge on human FL erythropoiesis is very limited. In this study, we sorted primary erythroblasts from FL cells and performed RNA sequencing (RNA-seq) analyses. We
Externí odkaz:
https://doaj.org/article/af5216d408df4c149200ef2798e7efc5
Autor:
Chengjie Gao, Huan Zhang, Yaomei Wang, Shihui Wang, Xinhua Guo, Yongshuai Han, Huizhi Zhao, Xiuli An
Publikováno v:
Cells, Vol 13, Iss 13, p 1149 (2024)
Erythropoiesis occurs first in the yolk sac as a transit “primitive” form, then is gradually replaced by the “definitive” form in the fetal liver (FL) during fetal development and in the bone marrow (BM) postnatally. While it is well known th
Externí odkaz:
https://doaj.org/article/8bbd712624a7458aa744f83e0b473beb
Autor:
Mengjia Li, Donghao Liu, Fumin Xue, Hengchao Zhang, Qianqian Yang, Lei Sun, Xiaoli Qu, Xiuyun Wu, Huizhi Zhao, Jing Liu, Qiaozhen Kang, Ting Wang, Xiuli An, Lixiang Chen
Publikováno v:
Haematologica, Vol 108, Iss 9 (2023)
Enhancer of zeste homolog 2 (EZH2) is the lysine methyltransferase of polycomb repressive complex 2 (PRC2) that catalyzes H3K27 tri-methylation. Aberrant expression and loss-of-function mutations of EZH2 have been demonstrated to be tightly associate
Externí odkaz:
https://doaj.org/article/8ca92380222144f5aa1fb05b45580a42
Autor:
Yumin Huang, John Hale, Yaomei Wang, Wei Li, Shijie Zhang, Jieying Zhang, Huizhi Zhao, Xinhua Guo, Jing Liu, Hongxia Yan, Karina Yazdanbakhsh, Gang Huang, Christopher D. Hillyer, Narla Mohandas, Lixiang Chen, Ling Sun, Xiuli An
Publikováno v:
Journal of Hematology & Oncology, Vol 11, Iss 1, Pp 1-12 (2018)
Abstract Background SF3B1 is a core component of splicing machinery. Mutations in SF3B1 are frequently found in myelodysplastic syndromes (MDS), particularly in patients with refractory anemia with ringed sideroblasts (RARS), characterized by isolate
Externí odkaz:
https://doaj.org/article/98f9bee7930c4d9a9b6d0398d4715a64
Autor:
Xiaoli Chen, Yiping Shen, Yonghui Gao, Huizhi Zhao, Xiaoming Sheng, Jizhen Zou, Va Lip, Hua Xie, Jin Guo, Hong Shao, Yihua Bao, Jianliang Shen, Bo Niu, James F Gusella, Bai-Lin Wu, Ting Zhang
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e54492 (2013)
BACKGROUND: Neural tube defects (NTDs) are one of the most common birth defects caused by a combination of genetic and environmental factors. Currently, little is known about the genetic basis of NTDs although up to 70% of human NTDs were reported to
Externí odkaz:
https://doaj.org/article/0afbeaeef77f408fbaff8c2bf7845a48
Autor:
Jing Zhang, Bing Liu, Xingpeng Jiang, Huizhi Zhao, Ming Fan, Zhenjie Fan, J Jack Lee, Tao Jiang, Tianzi Jiang, Sonya Wei Song
Publikováno v:
PLoS ONE, Vol 4, Iss 7, p e6274 (2009)
Accurate prediction of survival of cancer patients is still a key open problem in clinical research. Recently, many large-scale gene expression clusterings have identified sets of genes reportedly predictive of prognosis; however, those gene sets sha
Externí odkaz:
https://doaj.org/article/83e7f5a59722452b9f577552949a93b1
Publikováno v:
Epigenomics. 14:1249-1267
Aims: To investigate DNA methylation patterns in early and terminal stages of erythropoiesis, and to explore the function of differentially methylated genes in erythropoiesis and erythroid disorders. Materials & methods: Differential analysis of DNA
Autor:
Shihui Wang, Huizhi Zhao, Huan Zhang, Chengjie Gao, Xinhua Guo, Lixiang Chen, Cheryl Lobo, Karina Yazdanbakhsh, Shijie Zhang, Xiuli An
Publikováno v:
Journal of Cellular and Molecular Medicine. 26:2404-2416
Autor:
Narla Mohandas, Karina Yazdanbakhsh, Xinhua Guo, Lixiang Chen, Shijie Zhang, Donghao Liu, Xiuli An, Qian Qi, Christopher D. Hillyer, Patrick G. Gallagher, Xin Wei, Wei Li, Yong Cheng, Yaomei Wang, Xiaoli Qu, Vincent P. Schulz, Huizhi Zhao
Publikováno v:
Blood
Histone deacetylases (HDACs) are a group of enzymes that catalyze the removal of acetyl groups from histone and nonhistone proteins. HDACs have been shown to have diverse functions in a wide range of biological processes. However, their roles in mamm
Publikováno v:
Optical Fiber Technology. 75:103206