Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Huizhe Lu"'
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 207, Iss , Pp 111280- (2021)
As a top-selling neonicotinoid insecticide widely used in the field, thiamethoxam is an environmental pollutant because of the accumulation in ecosystem and has also been reported that it has potential risks to the health of mammals even humans. In o
Externí odkaz:
https://doaj.org/article/7ca4d73474b149ba8a4139273fd217ba
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 33, Iss 1, Pp 445-452 (2018)
GH20 human β-N-acetylhexosaminidases (hsHex) and GH84 human O-GlcNAcase (hOGA) are involved in numerous pathological processes and emerged as promising targets for drug discovery. Based on the catalytic mechanism and structure of the catalytic domai
Externí odkaz:
https://doaj.org/article/b351004002eb4830b655d63ea20c100d
Publikováno v:
Frontiers in Chemistry, Vol 7 (2019)
β-N-acetylhexosaminidases represent an important class of exoglycosidases and have emerged as the promising targets for drug and pesticide discovery. Among these, human O-GlcNAcase (hOGA) has been reported to be closely linked to several diseases su
Externí odkaz:
https://doaj.org/article/d34a3e68058949138e70bb01bae42d58
Publikováno v:
Frontiers in Chemistry, Vol 7 (2019)
β-N-acetyl-D-hexosaminidases have attracted significant attention due to their crucial role in diverse physiological functions including antibacterial synergists, pathogen defense, virus infection, lysosomal storage, and protein glycosylation. In pa
Externí odkaz:
https://doaj.org/article/80e75bf0dc694774bf63cd71055df2f0
Autor:
Shijie Du, Huizhe Lu, Dongyan Yang, Hong Li, Xilin Gu, Chuan Wan, Changqing Jia, Mian Wang, Xiuyun Li, Zhaohai Qin
Publikováno v:
Molecules, Vol 20, Iss 3, Pp 4071-4087 (2015)
A series of novel aromatic carboxylic acid amides were synthesized and tested for their activities against six phytopathogenic fungi by an in vitro mycelia growth inhibition assay. Most of them displayed moderate to good activity. Among them N-(2-(1H
Externí odkaz:
https://doaj.org/article/50894b3801974783ad51b50849e0a01d
Publikováno v:
Molecules, Vol 20, Iss 1, Pp 1088-1103 (2015)
A series of novel compounds, namely 1-(diethoxyphosphoryl)-3-(4-ones-1H-1,2,3-triazol-1-yl)propan-2-yl carboxylic esters, were designed on the basis of the diazafulvene intermediate of imidazole glycerol phosphate dehydratase (IGPD) and high-activity
Externí odkaz:
https://doaj.org/article/b71d3ec1e2e44cf883351e493e93ad5c
Autor:
Guanghui Zong, Xiaojing Yan, Jiawei Bi, Rui Jiang, Yinan Qin, Huizhu Yuan, Huizhe Lu, Yanhong Dong, Shuhui Jin, Jianjun Zhang
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0181646 (2017)
1,3,4-Thiadiazole and sugar-derived molecules have proven to be promising agrochemicals with growth promoting, insecticidal and fungicidal activities. In the research field of agricultural fungicide, applying union of active group we synthesized a ne
Externí odkaz:
https://doaj.org/article/7c7db7654dba48bb8a91231bab42c428
Publikováno v:
Molecules, Vol 23, Iss 5, p 1086 (2018)
Novel azamacrolides comprising the triazole moiety were synthesized and evaluated for their quorum sensing inhibitor activities on the Agrobacterium tumefaciens. It was found that the inhibition rate of compound Z12-3 at 200 mg/L (0.45 mM) can reach
Externí odkaz:
https://doaj.org/article/9d83d4e3bd4f48a0ad47025ae79b334b
Autor:
Jianli Wang, Meng Yuan, Changsheng Li, Bingjie Zhang, Jianhui Zhu, Xianghong Hao, Huizhe Lu, Yongqiang Ma
Publikováno v:
Journal of Colloid and Interface Science. 612:536-549