Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Huizhe Huang"'
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract Background Paired box 1 (PAX1) is a transcription factor and essential for the development of pharyngeal pouches-derived tissues, including thymus. PAX1 mutations are identified in Severe Combined Immunodeficiency (SCID) patients with Otofac
Externí odkaz:
https://doaj.org/article/48a94726aadc40899b5c41c68f91c98e
Autor:
Jiang Ren, Shuai Wang, Zhi Zong, Ting Pan, Sijia Liu, Wei Mao, Huizhe Huang, Xiaohua Yan, Bing Yang, Xin He, Fangfang Zhou, Long Zhang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Viruses, as opportunistic intracellular parasites, hijack the cellular machinery of host cells to support their survival and propagation. Numerous viral proteins are subjected to host-mediated post-translational modifications. Here, we demon
Externí odkaz:
https://doaj.org/article/e3e9e519f6b84b0e8f7d6e0867082a16
Autor:
Shu Su, Meng Jia, Yingni Yu, Hu Li, Wenwei Yin, Yi Lu, Rongzhong Huang, Rong Xiang, Huizhe Huang, Peng Hu
Publikováno v:
JMIR Public Health and Surveillance, Vol 10, p e49285 (2024)
BackgroundThe worldwide spread of monkeypox (mpox) has witnessed a significant increase, particularly in nonendemic countries. ObjectiveWe aimed to investigate the changing clinical symptoms associated with mpox from 1970 to 2023 and explore their i
Externí odkaz:
https://doaj.org/article/49860c5ef17144e2b4b76abd5713433d
Autor:
Yunpeng Wang, Yu Xu, Huijiao Zhang, Danyang Yin, Yiming Pan, Xiwen He, Shuaiting Li, Zhi Cheng, Gaohui Zhu, Ting Zhao, Huizhe Huang, Min Zhu
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2024)
IntroductionIndividuals with 17-beta-hydroxysteroid dehydrogenase type 3 (17β-HSD3) deficiency face a multitude of challenges, primarily concerning genital appearance, potential malignancy risks, and fertility issues. This study reports our findings
Externí odkaz:
https://doaj.org/article/acb440dc604f4c7e84ffdf379003a487
Autor:
Wenjie Zhong, Huaxiang Zhao, Wenbin Huang, Mengqi Zhang, Qian Zhang, Yue Zhang, Chong Chen, Zulihumaer Nueraihemaiti, Dilifeire Tuerhong, Huizhe Huang, Gulibaha Maimaitili, Feng Chen, Jiuxiang Lin
Publikováno v:
Genes and Diseases, Vol 8, Iss 5, Pp 689-697 (2021)
The Patched 1 (PTCH1) gene encodes a membrane receptor involved in the Hedgehog (Hh) signaling pathway, an abnormal state of which may result in congenital defects or human tumors. In this study, we conducted whole-exome sequencing on a three-generat
Externí odkaz:
https://doaj.org/article/0483e18d8154472bbab1376c06be6507
Autor:
Wenhua Yan, Tian Zhang, Shuaiting Li, Yunpeng Wang, Li Zhu, Yu Cao, Xiaofang Lai, Huizhe Huang
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 7, p 6327 (2023)
Areca nut has been listed as one of the most addictive substances, along with tobacco, alcohol and caffeine. Areca nut contains seven psychoactive alkaloids; however, the effects of these alkaloids on embryonic development and motor behavior are rare
Externí odkaz:
https://doaj.org/article/d950014f99ef4c9abcf8eaa67098f57c
Autor:
Ziran Qin, Xiuwu Fang, Wenhuan Sun, Zhenyu Ma, Tong Dai, Shuai Wang, Zhi Zong, Huizhe Huang, Heng Ru, Huasong Lu, Bing Yang, Shixian Lin, Fangfang Zhou, Long Zhang
Publikováno v:
Nature Immunology. 23:1193-1207
Innate antiviral immunity deteriorates with aging but how this occurs is not entirely clear. Here we identified SIRT1-mediated DNA-binding domain (DBD) deacetylation as a critical step for IRF3/7 activation that is inhibited during aging. Viral-stimu
Autor:
Gulibaha Maimaitili, Jiuxiang Lin, Huizhe Huang, Chong Chen, Huaxiang Zhao, Zulihumaer Nueraihemaiti, Wenbin Huang, Wenjie Zhong, Dilifeire Tuerhong, Yue Zhang, Feng Chen, Qian Zhang, Mengqi Zhang
Publikováno v:
Genes and Diseases, Vol 8, Iss 5, Pp 689-697 (2021)
The Patched 1 (PTCH1) gene encodes a membrane receptor involved in the Hedgehog (Hh) signaling pathway, an abnormal state of which may result in congenital defects or human tumors. In this study, we conducted whole-exome sequencing on a three-generat
Autor:
Ziran Qin, Lingfeng Lou, Bing Yang, Huizhe Huang, Shuai Wang, Tong Dai, Ting Pan, Huasong Lu, Fangfang Zhou, Long Zhang, Feng Chu
Publikováno v:
Nature Cell Biology. 23:718-732
Patients with Coronavirus disease 2019 exhibit low expression of interferon-stimulated genes, contributing to a limited antiviral response. Uncovering the underlying mechanism of innate immune suppression and rescuing the innate antiviral response re
Autor:
Yunpeng Wang, Zhi Cheng, Huan Zhang, Shuaiting Li, Yiming Pan, Weiyang Zhang, Siyuan Huang, Xiwen He, Fa Zou, Zhi Yuan, Wenhua Yan, Huizhe Huang
Publikováno v:
Toxicology and applied pharmacology. 449
Tri-n-butyl phosphate (TnBP) is a widely used organophosphate ester, but its effects on the regenerative process under damaging circumstances remain unknown. In the present study, zebrafish larvae were exposed to 0, 50, 100, 200 and 1000 μg/L TnBP,