Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Huiying Zhi"'
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0135738 (2015)
IgG immune complexes contribute to the etiology and pathogenesis of numerous autoimmune disorders, including heparin-induced thrombocytopenia, systemic lupus erythematosus, rheumatoid- and collagen-induced arthritis, and chronic glomerulonephritis. P
Externí odkaz:
https://doaj.org/article/3d2d7c3aed69436e949d5c0b6101daa2
Autor:
Yongwei Zheng, Tamara Adams, Huiying Zhi, Mei Yu, Renren Wen, Peter J Newman, Demin Wang, Debra K Newman
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0119739 (2015)
Receptor-mediated platelet activation requires phospholipase C (PLC) activity to elevate intracellular calcium and induce actin cytoskeleton reorganization. PLCs are classified into structurally distinct β, γ, δ, ε, ζ, and η isoforms. There are
Externí odkaz:
https://doaj.org/article/ee6d8127081545fd81da6f3bbe186adc
Publikováno v:
Blood Adv
Fetal/neonatal alloimmune thrombocytopenia (FNAIT) is a life-threatening bleeding disorder caused by maternal antibodies directed against paternally inherited antigens present on the surface of fetal platelets. The human platelet alloantigen HPA-1a (
Publikováno v:
Blood. 140:2828-2828
Autor:
Peter J. Newman, Aye Myat Myat Thinn, Brian R. Curtis, Bjørn Skogen, Jieqing Zhu, Huiying Zhi, Hartmut Weiler, Maria Therese Ahlen
Publikováno v:
Blood Advances. 2:3001-3011
Antibodies to platelet-specific antigens are responsible for 2 clinically important bleeding disorders: posttransfusion purpura and fetal/neonatal alloimmune thrombocytopenia (FNAIT). The human platelet-specific alloantigen 1a/1b (HPA-1a/1b; also kno
Publikováno v:
Genesis
Platelet Endothelial Cell Adhesion Molecule 1 (PECAM-1) is an adhesion and signaling receptor that is expressed on endothelial and hematopoietic cells and plays important roles in angiogenesis, vascular permeability, and regulation of cellular respon
Publikováno v:
Blood. 138:3153-3153
Fetal/neonatal alloimmune thrombocytopenia (FNAIT) is a life-threatening bleeding disorder caused by maternal alloantibodies directed against paternally inherited antigens present on the surface of fetal and neonatal platelets. The human platelet all
Autor:
Trude Victoria Mørtberg, Jan Terje Andersen, Gestur Vidarsson, Huiying Zhi, Tor B. Stuge, Stian Foss, Bjørn Skogen, Peter J. Newman, Terje E. Michaelsen, Maria Therese Ahlen
Publikováno v:
Blood. 138:1011-1011
Maternal alloantibodies to paternally inherited platelet antigens can cause fetal/neonatal alloimmune thrombocytopenia (FNAIT), rendering the fetus or newborn prone to bleeding and intracranial hemorrhage (ICH) with risk of lifelong disabilities or d
Autor:
Mortimer Poncz, Deborah L. French, Sridhar Rao, Brian R. Curtis, Peter J. Newman, Huiying Zhi, Nanyan Zhang, Chintan D Jobaliya
Publikováno v:
Blood. 127:675-680
Human platelet alloantigens (HPAs) reside on functionally important platelet membrane glycoproteins and are caused by single nucleotide polymorphisms in the genes that encode them. Antibodies that form against HPAs are responsible for several clinica
Publikováno v:
Blood. 134:97-97
Fetal/neonatal alloimmune thrombocytopenia (FNAIT) is a life-threatening bleeding disorder caused by maternal antibodies directed against paternally-inherited antigens present on the surface of fetal platelets. The human platelet alloantigen, HPA-1a