Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Huixiao, Fu"'
Publikováno v:
PLoS ONE, Vol 18, Iss 5, p e0286121 (2023)
This study monitored the presence of SARS-Cov-2 RNA on environmental surfaces in hospital wards housing patients with mild, severe, and convalescent Coronavirus Disease 2019 (COVID-19), respectively. From 29 October to 4 December 2021, a total of 787
Externí odkaz:
https://doaj.org/article/4ae53c69441c4cf5bcb3b99ed10f6d42
Autor:
Jian, Fu, Ziyao, He, Huixiao, Fu, Yufen, Xia, Inès, N'Go, Huayong, Lou, Jinglan, Wu, Weidong, Pan, Stéphane P, Vincent
Publikováno v:
Bioorganic and Medicinal Chemistry. 69
There is a dearth of tuberculosis (TB) drug development activity as current therapeutic treatments are inadequate due to the appearance of drug-resistant TB. The enzyme UDP-galactopyranose mutase (UGM) is involved in the biosynthesis of galactan whic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74162d67cf2af7d5bf7015a8de23a821
https://doi.org/10.1016/j.bmc.2022.116896
https://doi.org/10.1016/j.bmc.2022.116896
Autor:
Colleen D. Castro, Huixiao Fu, Tianlei Li, Marine Lacritick, Weidong Pan, Abdellatif Tikad, Erika A. Taylor, Stéphane P. Vincent, Jozafina Milicaj
The multistep synthesis of a novel ADP-7-azido-7-deoxy-l-glycero-β-d-manno-heptopyranoside 2a and several analogues as heptosyltransferase ligands is described. The synthesis of the key intermediate heptoside-1-β-phosphate 3a involved a β-stereose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5b93e024836183904cb4ad4e7a188c0
https://researchportal.unamur.be/en/publications/bda79e49-8ce3-48b1-a8f3-f3a3fcd61827
https://researchportal.unamur.be/en/publications/bda79e49-8ce3-48b1-a8f3-f3a3fcd61827
Publikováno v:
Organicbiomolecular chemistry. 19(8)
An in situ screening assay for UDP-galactopyranose mutase (UGM, an essential enzyme of M. tuberculosis cell wall biosynthesis) has been developed to discover novel UGM inhibitors. The approach is based on the amide-forming reaction of an amino acid c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::184a87eb277633d162a59a76bfba3b98
https://pubmed.ncbi.nlm.nih.gov/33565547
https://pubmed.ncbi.nlm.nih.gov/33565547
Autor:
Jian Fu, Weidong Pan, Stéphane P. Vincent, Yufen Xia, Iman Halloum, Marc Dieu, Huixiao Fu, Laurent Kremer
Publikováno v:
Chemical Communications. 53:10632-10635
In this study, we report a dynamic combinatorial approach alongwith highly efficient in situ screening to identify inhibitors of UDPgalactopyranosemutase (UGM), an essential enzyme involvedin mycobacterial cell wall biosynthesis. These two technologi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58c0b3ad4014e048b50dcb583af1d46f
https://doi.org/10.1039/c7cc05251k
https://doi.org/10.1039/c7cc05251k
Publikováno v:
Chembiochem : a European journal of chemical biology. 18(21)
Enzyme assays involving coupled pyruvate kinase (PK) have been used for many years to monitor the activity of major classes of enzymes including glycosyltransferases. Numerous potent inhibitors have been discovered and kinetically characterized thank
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e493e4a8845234f14761d1a2cf04ff0
https://pubmed.ncbi.nlm.nih.gov/28857455
https://pubmed.ncbi.nlm.nih.gov/28857455
Autor:
Sophie Laurent, Charlotte M. Sevrain, Huixiao Fu, Abdellatif Tikad, Jean-François Nierengarten, Stéphane P. Vincent
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany). 22(37)
The synthesis of unprecedented multimeric Kdo glycoclusters based on fullerene and calix[4]arene central scaffolds is reported. The compounds were used to study the mechanism and scope of multivalent glycosyltransferase inhibition. Multimeric mannosi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::598927a0c3dd6d9b5bc1f418644b1d34
https://pubmed.ncbi.nlm.nih.gov/27516128
https://pubmed.ncbi.nlm.nih.gov/27516128