Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Huitu, Zhang"'
Publikováno v:
Microbial Cell Factories, Vol 19, Iss 1, Pp 1-13 (2020)
Abstract Background Bacillus licheniformis 2709 is extensively applied as a host for the high-level production of heterologous proteins, but Bacillus cells often possess unfavorable wild-type properties, such as production of viscous materials and fo
Externí odkaz:
https://doaj.org/article/d158e222ca3c405caa8e77647b6abbe5
Publikováno v:
Microbial Cell Factories, Vol 18, Iss 1, Pp 1-12 (2019)
Abstract Background Our laboratory has constructed a Bacillus licheniformis strain that secretes alkaline protease (AprE) with excellent enzymatic properties. B. licheniformis is generally regarded as safe and has a high industrial exoenzyme secretio
Externí odkaz:
https://doaj.org/article/781f4f5bd1f64ecbafc5acaae71c882d
Site-Directed Mutation of Salicylate Decarboxylase Gene and Mechanism of Ginkgo Acid Decarboxylation
Autor:
Yuanyuan Song, Yanying Hu, Jiaxin Li, Lin Wang, Wenjie Jing, Liming Zhang, Yujie Dai, Shiru Jia, Xuan Meng, Huitu Zhang
Publikováno v:
The Protein Journal. 42:1-13
Ginkgo seed is an important Chinese medicine and food resource in China, but the toxicity of ginkgo acid in it limits its application. Previous studies have found that salicylic acid decarboxylase (Sdc) has a decarboxylation degradation effect on gin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32909d537744171f6e37b0a26e49c5ed
https://doi.org/10.1007/s10930-022-10086-1
https://doi.org/10.1007/s10930-022-10086-1
Publikováno v:
International Journal of Biological Macromolecules. 211:580-591
Misfolding and aggregation of α-synuclein (α-syn) play a key role in the pathogenesis of Parkinson's disease (PD). Herein, the inhibitory effect of ulvan on α-syn fibrillogenesis was studied using thioflavin T fluorescence and atomic force microsc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cb5d7159ae00f8d786429ed93e0c9fe
https://doi.org/10.1016/j.ijbiomac.2022.05.045
https://doi.org/10.1016/j.ijbiomac.2022.05.045
Autor:
Huiying Zhou, Fuping Lu, Honglei Fang, Sun Yanqing, Cuixia Zhou, Huitu Zhang, Guangcheng Yang
Publikováno v:
International Journal of Biological Macromolecules. 166:1491-1498
Bacillus licheniformis 2709 is the major alkaline protease producer, which has great potential value of industrial application, but how the high-producer can be regulated rationally is still not completely understood. It's meaningful to understand th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2117a88fd70112899e62ee76c1b8553d
https://doi.org/10.1016/j.ijbiomac.2020.11.028
https://doi.org/10.1016/j.ijbiomac.2020.11.028
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 9, Iss 1, Pp 1768-1773 (2013)
At least 65% of all small molecule drugs on the market today are natural products, however, re-isolation of previously identified and characterized compounds has become a serious impediment to the discovery of new bioactive natural products. Here, ge
Externí odkaz:
https://doaj.org/article/312e195cd467427ab3ddc4dfa8ffb982
Autor:
Huitu Zhang, Shan He, Jingcheng Sang, Xiaoqing Zhang, Fuping Lu, Wei Cui, Luying Jiang, Fufeng Liu, Li Li
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 39:6440-6451
Previous studies have indicated that 5-hydroxycyclopenicillone (HCP), an active compound derived from marine sponge, could inhibit oligomerization of amyloid β-protein (Aβ). However, the molecular basis for the interaction between HCP and Aβ remai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82d8a5d2040d97e7bffe01b04d342d67
https://doi.org/10.1080/07391102.2020.1799863
https://doi.org/10.1080/07391102.2020.1799863
Publikováno v:
International journal of biological macromolecules. 193
Bacillus licheniformis 2709 is a potential cell factory for the production of alkaline protease AprE, which has important value in industrial application but still lacks sufficient production capacity. To address this problem, we investigated the eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::378c1506b7fb7ac06860ea30261cc3f1
https://pubmed.ncbi.nlm.nih.gov/34742839
https://pubmed.ncbi.nlm.nih.gov/34742839
Autor:
Jing Zhang, Huan Liu, Xiaonong Wu, Yujie Dai, Haikuan Wang, Cuixia Zhou, Rong Yue, Huitu Zhang, Tongwei Sun, Fuping Lu, Ying Zhang, Guoguo Wu, Fufeng Liu
Publikováno v:
Protein Engineering, Design and Selection. 32:375-383
To improve the proteolytic stability of the lipase LIP2 from Yarrowia lipolytica, the peptide bonds susceptible to trypsin in LIP2 were analyzed by tandem mass spectrometry and redesigned by site-directed mutagenesis. Different variants of the enzyme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fe68aeab965e120fc7fd9ed3dab3935
https://doi.org/10.1093/protein/gzaa001
https://doi.org/10.1093/protein/gzaa001
Publikováno v:
Microbial Cell Factories, Vol 18, Iss 1, Pp 1-12 (2019)
Microbial Cell Factories
Microbial Cell Factories
Background Our laboratory has constructed a Bacillus licheniformis strain that secretes alkaline protease (AprE) with excellent enzymatic properties. B. licheniformis is generally regarded as safe and has a high industrial exoenzyme secretion capacit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28dd098cc51e8ff69a19b37f90431b40
http://link.springer.com/article/10.1186/s12934-019-1174-1
http://link.springer.com/article/10.1186/s12934-019-1174-1