Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Huisuk Yang"'
Autor:
Youseong Kim, Hye Su Min, Jiwoo Shin, Jeehye Nam, Geonwoo Kang, Jeeho Sim, Huisuk Yang, Hyungil Jung
Publikováno v:
Biomaterials Research, Vol 26, Iss 1, Pp 1-14 (2022)
Abstract Background Dissolving microneedle (DMN) is a transdermal drug delivery system that creates pore in the skin and directly deliver drug through the pore channel. DMN is considered as one of the promising system alternatives to injection becaus
Externí odkaz:
https://doaj.org/article/f7b51cd4f3dd47358adf4736e673d469
Autor:
Jeeho Sim, SeongDae Gong, Geonwoo Kang, Mingyu Jang, Huisuk Yang, Jaesung Park, Youngchan Kim, Hyunkyu Lee, Hyunji Jung, Youseong Kim, Chansol Jeon, Hyeri Ahn, Minkyung Kim, Jaibyung Choi, Ho Lee, Hyungil Jung
Publikováno v:
Pharmaceutics, Vol 14, Iss 12, p 2804 (2022)
Topical liquid formulations, dissolving microneedles (DMNs), and microscale needles composed of biodegradable materials have been widely used for the transdermal delivery of active compounds for skincare. However, transdermal active compound delivery
Externí odkaz:
https://doaj.org/article/06ba470fa66140988dc20241a1f61111
Autor:
Jeeho Sim, Geonwoo Kang, Huisuk Yang, Mingyu Jang, Youseong Kim, Hyeri Ahn, Minkyung Kim, Hyungil Jung
Publikováno v:
Polymers, Vol 14, Iss 19, p 4027 (2022)
Teriparatide acetate (TA), which directly promotes bone formation, is subcutaneously injected to treat osteoporosis. In this study, TA with a once-weekly administration regimen was loaded on dissolving microneedles (DMNs) to effectively deliver it to
Externí odkaz:
https://doaj.org/article/54e8ab77b4a34b8eb7b25cd0a926c4d0
Autor:
Jungyoon Ohn, Mingyu Jang, Bo Mi Kang, Huisuk Yang, Jin Tae Hong, Kyu Han Kim, Ohsang Kwon, Hyungil Jung
Publikováno v:
Advanced Science, Vol 8, Iss 14, Pp n/a-n/a (2021)
Abstract Chronic inflammatory skin diseases (CISDs) negatively impact a large number of patients. Injection of triamcinolone acetonide (TA), an anti‐inflammatory steroid drug, directly into the dermis of diseased skin using needle‐syringe systems
Externí odkaz:
https://doaj.org/article/f638a2a3f7e141ca925a75959b1f8ffd
Autor:
Chansol Jeon, Jaibyung Choi, Jiwoo Shin, Hye Su Min, Jeehye Nam, Seonghun Jeon, Jeongin Kim, Youseong Kim, Jeeho Sim, Hyeri Ahn, Minkyung Kim, Huisuk Yang, Hyungil Jung
Publikováno v:
Acta Biomaterialia. 160:112-122
Autor:
Seorin Juhng, Jieun Song, Jeongyun You, Jihyun Park, Huisuk Yang, Mingyu Jang, Geonwoo Kang, Jiwoo Shin, Hyuk Wan Ko, Hyungil Jung
Publikováno v:
Lab on a Chip. 23:2378-2388
The triple layer system (TLM) is a novel three layer composition dissolving microneedle which enhances drug efficacy and bioavailability, where each layer is designed to maximize the microneedle insertion and drug delivery.
Autor:
Chisong Lee, Jinkyung Kim, Daniel Junmin Um, Youseong Kim, Hye Su Min, Jiwoo Shin, Jee Hye Nam, Geonwoo Kang, Mingyu Jang, Huisuk Yang, Hyungil Jung
Publikováno v:
Pharmaceutics, Vol 13, Iss 7, p 1058 (2021)
Dissolving microneedles (DMNs) have been used as an alternative drug delivery system to deliver therapeutics across the skin barrier in a painless manner. In this study, we propose a novel heat-melting method for the fabrication of hydrophobic poly(l
Externí odkaz:
https://doaj.org/article/88ab497a4aac49cd9115b3739513e719
Publikováno v:
Micromachines, Vol 12, Iss 2, p 167 (2021)
(1) Background: Dissolving microneedles (DMNs), a transdermal drug delivery system, have been developed to treat various diseases in a minimally invasive, painless manner. However, the currently available DMNs are based on burst release systems due t
Externí odkaz:
https://doaj.org/article/e82ffdacfab04f099b0f647437c0dd66
Autor:
Huisuk Yang, Geonwoo Kang, Mingyu Jang, Daniel Junmin Um, Jiwoo Shin, Hyeonjun Kim, Jintae Hong, Hyunji Jung, Hyemyoung Ahn, Seongdae Gong, Chisong Lee, Ui-Won Jung, Hyungil Jung
Publikováno v:
Pharmaceutics, Vol 12, Iss 11, p 1067 (2020)
Lidocaine is a local anesthetic agent used in the form of injection and topical cream. However, these formulation types have limitations of being either painful or slow-acting, thereby hindering effective and complete clinical performance of lidocain
Externí odkaz:
https://doaj.org/article/d28ea7d382f4497caba9a1f6b05b9100
Autor:
Jeongyun You, Seorin Juhng, Jieun Song, Jihyun Park, Mingyu Jang, Geonwoo Kang, Huisuk Yang, Hye Su Min, Jiwoo Shin, Seri Lee, Hyuk Wan Ko, Hyungil Jung
Publikováno v:
Advanced Healthcare Materials. 12
Liraglutide, a human glucagon-like peptide-1 analog, is promising for safely treating type 2 diabetes mellitus (T2DM), compared to insulin, by significantly reducing the risk of glucose-dependent hypoglycemia. Concerns related to injection prevent T2