Zobrazeno 1 - 10
of 183
pro vyhledávání: '"Huiqing, Zhou"'
Autor:
Dulce Lima Cunha, Hajrah Sarkar, Jonathan Eintracht, Philippa Harding, Jo Huiqing Zhou, Mariya Moosajee
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 33, Iss , Pp 240-253 (2023)
Congenital aniridia is a rare, pan-ocular disease causing severe sight loss, with only symptomatic intervention offered to patients. Approximately 40% of aniridia patients present with heterozygous nonsense variants in PAX6, resulting in haploinsuffi
Externí odkaz:
https://doaj.org/article/98e828503cb54ef894c2376858eda553
Autor:
Julian A. Arts, Siebren Frölich, Jos G.A. Smits, Huiqing Zhou, Joost H.A. Martens, Simon J. van Heeringen, Rebecca R. Snabel, Branco M.H. Heuts
Publikováno v:
F1000Research, Vol 12 (2023)
The recent development of single-cell techniques is essential to unravel complex biological systems. By measuring the transcriptome and the accessible genome on a single-cell level, cellular heterogeneity in a biological environment can be deciphered
Externí odkaz:
https://doaj.org/article/48bec8de53344c7f8dd77ff0ab226379
Publikováno v:
BMJ Open, Vol 13, Iss 11 (2023)
Introduction Blood blister-like aneurysm (BBA) is a special type of intracranial aneurysm with relatively low morbidity and high mortality. Various microsurgical techniques and endovascular approaches have been reported, but the optimal management re
Externí odkaz:
https://doaj.org/article/005c16e217414bcdb1e18466b2b0b045
Autor:
Christian Osterburg, Marco Ferniani, Dario Antonini, Ann-Sophie Frombach, Ludovica D’Auria, Susanne Osterburg, Rebecca Lotz, Frank Löhr, Sebastian Kehrloesser, Huiqing Zhou, Caterina Missero, Volker Dötsch
Publikováno v:
Cell Death and Disease, Vol 14, Iss 4, Pp 1-18 (2023)
Abstract The transcription factor p63 shares a high sequence identity with the tumour suppressor p53 which manifests itself in high structural similarity and preference for DNA sequences. Mutations in the DNA binding domain (DBD) of p53 have been stu
Externí odkaz:
https://doaj.org/article/8382378dde424318bf3ab9556e94faf5
Autor:
Jos G A Smits, Dulce Lima Cunha, Maryam Amini, Marina Bertolin, Camille Laberthonnière, Jieqiong Qu, Nicholas Owen, Lorenz Latta, Berthold Seitz, Lauriane N Roux, Tanja Stachon, Stefano Ferrari, Mariya Moosajee, Daniel Aberdam, Nora Szentmary, Simon J van Heeringen, Huiqing Zhou
Publikováno v:
PLoS Biology, Vol 21, Iss 10, p e3002336 (2023)
The transparent corneal epithelium in the eye is maintained through the homeostasis regulated by limbal stem cells (LSCs), while the nontransparent epidermis relies on epidermal keratinocytes for renewal. Despite their cellular similarities, the prec
Externí odkaz:
https://doaj.org/article/c523fd35c9044ca68bcfe92e2129b496
Publikováno v:
BMJ Open, Vol 13, Iss 8 (2023)
Introduction Chronic subdural haematoma (CSDH) is one of the most common neurosurgical emergencies, especially in the elderly population. Surgery is the mainstay of treatment for CSDH. Some studies have suggested that some specific surgical strategie
Externí odkaz:
https://doaj.org/article/465d1af4735947fcb652c4c2452b6205
Publikováno v:
BMC Neurology, Vol 23, Iss 1, Pp 1-7 (2023)
Abstract Background Early hematoma expansion (HE) occurs in 20 to 40% of spontaneous intracerebral hemorrhage (ICH) patients and is a primary determinant of early deterioration and poor prognosis. Previous studies have shown that inflammation is a ma
Externí odkaz:
https://doaj.org/article/c83d8cc01fd24d778daf14118db3353a
Autor:
Isabelle Petit, Ayelet Levy, Soline Estrach, Chloé C. Féral, Andrea Gonçalves Trentin, Florent Dingli, Damarys Loew, Jieqiong Qu, Huiqing Zhou, Clotilde Théry, Céline Prunier, Daniel Aberdam, Olivier Ferrigno
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract Fibroblast growth factor-2 (FGF2) has multiple roles in cutaneous wound healing but its natural low stability prevents the development of its use in skin repair therapies. Here we show that FGF2 binds the outer surface of dermal fibroblast (
Externí odkaz:
https://doaj.org/article/6f3c4cf3711b41db9cbe10a027fef673
Autor:
Niclas Fester, Elisabeth Zielonka, Jakob Goldmann, Ann-Sophie Frombach, Uta Müller-Kuller, Niklas Gutfreund, Kristina Riegel, Jos G. A. Smits, Enrico Schleiff, Krishnaraj Rajalingam, Huiqing Zhou, Stefan Simm, Volker Dötsch
Publikováno v:
Cell Death and Disease, Vol 13, Iss 3, Pp 1-10 (2022)
Abstract Specialized surveillance mechanisms are essential to maintain the genetic integrity of germ cells, which are not only the source of all somatic cells but also of the germ cells of the next generation. DNA damage and chromosomal aberrations a
Externí odkaz:
https://doaj.org/article/841bc32e7e0f40afa499d067f945af6a
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundCases of lateral ventricular ectopic schwannomas (LVES) are extremely rare, with only 23 cases reported thus far. This study aimed to obtain a better understanding of the disease.MethodsWe reported a rare case of LVES, in which the patient
Externí odkaz:
https://doaj.org/article/c0e76da7bfd4471193a35bb882f7979f