Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Huimou Chen"'
Autor:
Huimou Chen, Jing Hu, Xilin Xiong, Hongling Chen, Qiaofang Liao, Biaojun Lin, Yusong Chen, Yanting Peng, Yang Li, Di Cheng, Zhihua Li
Publikováno v:
Cell Death and Disease, Vol 15, Iss 7, Pp 1-14 (2024)
Abstract Ewing’s sarcoma (ES) represents a rare yet exceedingly aggressive neoplasm that poses a significant health risk to the pediatric and adolescent population. The clinical outcomes for individuals with relapsed or refractory ES are notably ad
Externí odkaz:
https://doaj.org/article/05846765d327427ebeaa63f51657b9a9
Autor:
Huimou Chen, Jing Hu, Xilin Xiong, Hongling Chen, Biaojun Lin, Yusong Chen, Yang Li, Di Cheng, Zhihua Li
Publikováno v:
Cell Death and Disease, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Ewing’s sarcoma (ES) is a rare and highly aggressive malignant tumor arising from bone and soft tissue. Suffering from intractable or recurrent diseases, the patients’ therapy options are very limited. It is extremely urgent to identify
Externí odkaz:
https://doaj.org/article/2fc1b5f5034b42e7936ba0c4fea2a725
Autor:
Chengtao Sun, Mengzhen Li, Lian Zhang, Feifei Sun, Huimou Chen, Yanjie Xu, Yingxia Lan, Li Zhang, Suying Lu, Jia Zhu, Junting Huang, Juan Wang, Yang Hu, Yanfen Feng, Yizhuo Zhang
Publikováno v:
Cell Death and Disease, Vol 13, Iss 6, Pp 1-13 (2022)
Abstract With the intensive therapeutic strategies, diffuse large B-cell lymphoma (DLBCL) is still a fatal disease due to its progressive characteristics. Indoleamine 2,3-dioxygenase 1 (IDO1) is a key regulator that catalyzes the commitment step of t
Externí odkaz:
https://doaj.org/article/4519a5be84dc495383d81ba0da34d85a
Autor:
Binbin Chen, Huimou Chen, Suying Lu, Xiaoqin Zhu, Yi Que, Yu Zhang, Junting Huang, Li Zhang, Feifei Sun, Juan Wang, Jia Zhu, Zijun Zhen, Yizhuo Zhang
Publikováno v:
Cell Death and Disease, Vol 13, Iss 4, Pp 1-13 (2022)
Abstract Ewing sarcoma (EwS) is an aggressive tumor that affects children and young adults. Patients with relapsed/refractory diseases have limited treatment options. Targeting the driver fusion oncoproteins of EwS remains a technical problem. Epigen
Externí odkaz:
https://doaj.org/article/c9897c1e429b473db8ba6dc177f5615a
The Efficacy and Safety of Anlotinib in Pediatric Patients With Refractory or Recurrent Solid Tumors
Autor:
Suying Lu, Ye Hong, Huimou Chen, Liuhong Wu, Feifei Sun, Juan Wang, Jia Zhu, Yi Que, Lian Zhang, Zijun Zhen, Xiaofei Sun, Junting Huang, Yizhuo Zhang
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Objective: Refractory or recurrent pediatric solid tumors lack effective treatments, and are associated with dismal outcomes. Hence, there is an urgent need for a novel therapeutic strategy. This study aimed to evaluate the efficacy and safety of anl
Externí odkaz:
https://doaj.org/article/e2b6278675ff447b982de353119692fa
Autor:
Yanan Lu, Dongni Xu, Jintao Peng, Zhaofan Luo, Chujie Chen, Yuqing Chen, Huimou Chen, Minghui Zheng, Peihong Yin, Zhi Wang
Publikováno v:
EBioMedicine, Vol 44, Iss , Pp 403-418 (2019)
Background: Pancreatic ductal adenocarcinoma (PDAC) is an aggressive disease with poor prognosis, and gemcitabine-based chemotherapy remains an effective option for the majority of PDAC patients. Hepatocyte nuclear factor 1α (HNF1A) is a tumor-suppr
Externí odkaz:
https://doaj.org/article/080d32df613840f5904288dfe197a324
Autor:
Suying Lu, Xiaoqin Zhu, Wei Li, Huimou Chen, Dalei Zhou, Zijun Zhen, Feifei Sun, Junting Huang, Jia Zhu, Juan Wang, Yizhuo Zhang, Xiaofei Sun
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
PurposeThis retrospective study aimed to investigate the relationships between the methylenetetrahydrofolate reductase (MTHFR) C677T/A1298C and high-dose methotrexate (HD-MTX)-related toxicities in pediatric non-Hodgkin lymphoma (NHL) patients.Patien
Externí odkaz:
https://doaj.org/article/d9ac607caa094d0ab93336403cf7586c
Autor:
Huimou Chen, Jing Hu, Juan Wang, Juan Liu, Binbin Chen, Yu Zhang, Mengjia Song, Mengzhen Li, Ye Hong, Feifei Sun, Junting Huang, Jia Zhu, Zijun Zhen, Yi Que, Suying Lu, Yizhuo Zhang
Background:Ewing's sarcoma (ES) is a rare and highly aggressive malignant tumor arising from bone and soft tissue. However, driver genes in ES have not been fully identified. It is extremely urgent to identify new tumor markers for ES and transform t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38ef21c1ebe7a7ebd126bc67ffaeba29
https://doi.org/10.21203/rs.3.rs-2330053/v1
https://doi.org/10.21203/rs.3.rs-2330053/v1
Autor:
Junting Huang, Xiaoqin Zhu, Wei Li, Dalei Zhou, Jia Zhu, Feifei Sun, Jinqiu Guan, Zijun Zhen, Yizhuo Zhang, Juan Wang, Xiaofei Sun, Huimou Chen, Suying Lu
Publikováno v:
Leukemia & Lymphoma. 62:2374-2382
This study evaluated the influence of MTHFR C677T/A1298C polymorphisms on the survival of pediatric NHL. We enrolled 374 patients including 283 males and 91 females between 2014 and 2020. The media...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a8d54dddffb4bbf6a3ee5c84cbb0929e
https://doi.org/10.1080/10428194.2021.1927017
https://doi.org/10.1080/10428194.2021.1927017
Autor:
Jia Zhu, Chengtao Sun, Chao Zhang, Wei Li, Feifei Sun, Xing Zhang, Zijun Zhen, Juan Wang, Junting Huang, Yizhuo Zhang, Xiaofei Sun, Ruiqing Cai, Liuhong Wu, Huimou Chen, Suying Lu
Publikováno v:
Cancer Management and Research. 12:12123-12136
Purpose The goal of the current study was to identify potential prognostic biomarkers of rhabdomyosarcoma (RMS). Materials and Methods We screened chip sequencing datasets of RMS through the gene expression omnibus (GEO) database. A total of 74 RMS p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d50e79ad6498d69199c58152b6c075c
https://doi.org/10.2147/cmar.s265779
https://doi.org/10.2147/cmar.s265779