Zobrazeno 1 - 10
of 135
pro vyhledávání: '"Huili Hu"'
Autor:
Beibei Guo, Xiaohan Huo, Xueyong Xie, Xiaohui Zhang, Jiabei Lian, Xiyu Zhang, Yaoqin Gong, Hao Dou, Yujia Fan, Yunuo Mao, Jinshen Wang, Huili Hu
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract CUL4B, a crucial scaffolding protein in the largest E3 ubiquitin ligase complex CRL4B, is involved in a broad range of physiological and pathological processes. While previous research has shown that CUL4B participates in maintaining intesti
Externí odkaz:
https://doaj.org/article/dd6c534e2012490b863651d98b8ff9c6
Autor:
Beibei Guo, Yawen Zheng, Yujia Fan, Yang Yang, Yuxing Wang, Liping Qin, Yachun An, Xiaoran Xu, Xiyu Zhang, Gongping Sun, Hao Dou, Changshun Shao, Yaoqin Gong, Baichun Jiang, Huili Hu
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 53, Iss , Pp 101005- (2024)
Colorectal cancer (CRC) stands as a prevalent malignancy globally. A pivotal event in CRC pathogenesis involves the loss-of-function mutation in the APC gene, leading to the formation of benign polyps. Despite the well-established role of APC, the co
Externí odkaz:
https://doaj.org/article/4fd74afd22c64f028c84d6f647d32cae
Autor:
Zishan Hong, Jing Xie, Huili Hu, Yuying Bai, Xia Hu, Tingting Li, Jinlian Chen, Jun Sheng, Yang Tian
Publikováno v:
Journal of Future Foods, Vol 3, Iss 4, Pp 383-391 (2023)
Diabetes mellitus (DM) is a chronic metabolic disease characterized by hyperglycemia, which poses a serious threat to human health. Moringa oleifera Lam is a medicinal and edible plant with various physiological functions. However, its main hypoglyce
Externí odkaz:
https://doaj.org/article/25c052b11a9b4b47b6bfd60db05dd372
Autor:
Yankun Zhang, Yuchen Fan, Huili Hu, Xiaohui Zhang, Zehua Wang, Zhuanchang Wu, Liyuan Wang, Xiangguo Yu, Xiaojia Song, Peng Xiang, Xiaodong Zhang, Tixiao Wang, Siyu Tan, Chunyang Li, Lifen Gao, Xiaohong Liang, Shuijie Li, Nailin Li, Xuetian Yue, Chunhong Ma
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Mitochondria dysfunction contributes to acute liver injuries, and mitochondrial regulators, such as PGC-1α and MCJ, affect liver regeneration. Therefore, identification of mitochondrial modulators may pave the way for developing therapeutic
Externí odkaz:
https://doaj.org/article/b9d2b1c9541949d3b5b30170360f89b2
Autor:
Annie S. P. Yang, Devanjali Dutta, Kai Kretzschmar, Delilah Hendriks, Jens Puschhof, Huili Hu, Kim E. Boonekamp, Youri van Waardenburg, Susana M. Chuva de Sousa Lopes, Geert-Jan van Gemert, Johannes H. W. de Wilt, Teun Bousema, Hans Clevers, Robert W. Sauerwein
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Plasmodium falciparum (Pf) parasite development in liver represents the initial step of the life-cycle in the human host after a Pf-infected mosquito bite. While an attractive stage for life-cycle interruption, understanding of parasite-hepa
Externí odkaz:
https://doaj.org/article/5c88670c6cde4830afc419a55a86cad4
Autor:
Yuxing Wang, Ru Wang, Xiaohe Liu, Menghao Liu, Lili Sun, Xiaohua Pan, Huili Hu, Baichun Jiang, Yongxin Zou, Qiao Liu, Yaoqin Gong, Molin Wang, Gongping Sun
Publikováno v:
Oncogenesis, Vol 12, Iss 1, Pp 1-13 (2023)
Abstract Cancer relapse and metastasis are major obstacles for effective treatment. One important mechanism to eliminate cancer cells is to induce apoptosis. Activation of executioner caspases is the key step in apoptosis and was considered “a poin
Externí odkaz:
https://doaj.org/article/2ee9e0885744472aaeeff2adac53092c
Autor:
Ru Wang, Yuxing Wang, Xiaohe Liu, Menghao Liu, Lili Sun, Xiaohua Pan, Huili Hu, Baichun Jiang, Yongxin Zou, Qiao Liu, Yaoqin Gong, Molin Wang, Gongping Sun
Publikováno v:
Cell Death and Disease, Vol 14, Iss 6, Pp 1-12 (2023)
Abstract Chemotherapy is a common strategy to treat cancer. However, acquired resistance and metastasis are the major obstacles to successful treatment. Anastasis is a process by which cells survive executioner caspase activation when facing apoptoti
Externí odkaz:
https://doaj.org/article/660acc5c85ea4ee9914bbdb46d99ef73
Autor:
Min Liu, Yang Zhang, Ping Zhan, Wenjuan Sun, Chuanqiao Dong, Xiaohan Liu, Yujie Yang, Xiaojie Wang, Yusheng Xie, Chengjiang Gao, Huili Hu, Benkang Shi, Ziying Wang, Chun Guo, Fan Yi
Publikováno v:
Pharmacological Research, Vol 198, Iss , Pp 107009- (2023)
Although hyperhomocysteinemia (hHcys) has been recognized as an important independent risk factor in the progression of end-stage renal disease and the development of cardiovascular complications related to end-stage renal disease, the mechanisms tri
Externí odkaz:
https://doaj.org/article/b75d1c61ff964de882682ddef23b59b2
Autor:
Li Wang, Junlei Han, Weiguang Su, Anqing Li, Wenxian Zhang, Huimin Li, Huili Hu, Wei Song, Chonghai Xu, Jun Chen
Publikováno v:
Microsystems & Nanoengineering, Vol 9, Iss 1, Pp 1-13 (2023)
Abstract Animal models and static cultures of intestinal epithelial cells are commonly used platforms for exploring mercury ion (Hg(II)) transport. However, they cannot reliably simulate the human intestinal microenvironment and monitor cellular phys
Externí odkaz:
https://doaj.org/article/4447ff1fddc94e50b8c97d4ef472660b
Autor:
Haijuan Xiao, Yiqing Miao, Linlin Liu, Wenya Feng, Shuping Liu, Lingyun Guo, Xin Guo, Tianming Chen, Bing Hu, Huili Hu, Fang Xu, Lianlian Han, Lili Ren, Wei Li, Gang Liu
Publikováno v:
BMC Infectious Diseases, Vol 22, Iss 1, Pp 1-10 (2022)
Abstract Background Central nervous system candidiasis due to Candida albicans (CNSC) in children is easily misdiagnosed and is associated with poor outcomes and a high mortality rate. There is no big data research or systematic review of CNSC. Metho
Externí odkaz:
https://doaj.org/article/99976c8b19bb448e9cd0505ff011398f