Zobrazeno 1 - 10
of 292
pro vyhledávání: '"Huile Gao"'
Autor:
Xueying Liu, Hao Wang, Zhaofeng Li, Jiamei Li, Siqin He, Chuan Hu, Yujun Song, Huile Gao, Yi Qin
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-18 (2024)
Abstract Breast cancer is the most common malignant tumor that threatens women’s life and health, and metastasis often occurs in the advanced stage of breast cancer, leading to pathological bone destruction and seriously reducing patient quality of
Externí odkaz:
https://doaj.org/article/cf47e45ad1d2464d8a582429d748fb4b
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 9, Pp 4102-4117 (2024)
Tumor vaccine, a promising modality of tumor immunotherapy, needs to go through the process of tumor antigen generation and loading, antigen drainage to lymph nodes (LNs), antigen internalization by dendritic cells (DCs), DC maturation, and antigen c
Externí odkaz:
https://doaj.org/article/61bcdf2b95ba4d0aa73d5c9f523d4fc0
Autor:
Qianru Rao, Yujie Xu, Xiaorong Wang, Hang Luo, Haoqi Li, Jingyuan Xiong, Huile Gao, Guo Cheng
Publikováno v:
SusMat, Vol 4, Iss 4, Pp n/a-n/a (2024)
Abstract Dysfunction of the hypothalamus is associated with endocrine imbalances, growth abnormalities, and reproductive disorders. However, there is a lack of targeted treatment strategies focused on the hypothalamus. In this study, we constructed a
Externí odkaz:
https://doaj.org/article/78d69c50c1034aa8b18dd96a4dad41ce
Autor:
Siqin He, Lulu Wang, Dongxu Wu, Fan Tong, Huan Zhao, Hanmei Li, Tao Gong, Huile Gao, Yang Zhou
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 2, Pp 765-780 (2024)
A major challenge facing photodynamic therapy (PDT) is that the activity of the immune-induced infiltrating CD8+ T cells is subject to the regulatory T lymphocytes (Tregs), leaving the tumor at risk of recurrence and metastasis after the initial abla
Externí odkaz:
https://doaj.org/article/a609388ace9b4df89843d93ef54022a3
Autor:
Rui Qu, Wenxuan Du, Shuyao Li, Wei Li, Guangfei Wei, Zhoujiang Chen, Huile Gao, Sanjun Shi, Liang Zou, Hanmei Li
Publikováno v:
Heliyon, Vol 10, Iss 7, Pp e29101- (2024)
A special microenvironment called the “pre-metastatic niche” is thought to help primary tumor cells migrate to new tissues and invade them, in part because the normal barrier function of the vascular endothelium is compromised. While the primary
Externí odkaz:
https://doaj.org/article/83f814caf1d24b619cae010065dc2f78
Autor:
Fan Tong, Haili Hu, Yanyan Xu, Yang Zhou, Rou Xie, Ting Lei, Yufan Du, Wenqin Yang, Siqin He, Yuan Huang, Tao Gong, Huile Gao
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 8, Pp 3471-3488 (2023)
As known, the benefits of photothermal therapy (PTT) are greatly limited by the heat tolerance of cancer cells resulting from overexpressed heat shock proteins (HSPs). Then HSPs further trigger the formation of stress granules (SGs) that regulate pro
Externí odkaz:
https://doaj.org/article/202867aa7a3749e88b6e1ca227045170
Autor:
Zhaofeng Li, Peixin Liu, Wei Chen, Xueying Liu, Fan Tong, Junhui Sun, Yang Zhou, Ting Lei, Wenqin Yang, Dong Ma, Huile Gao, Yi Qin
Publikováno v:
Journal of Nanobiotechnology, Vol 21, Iss 1, Pp 1-14 (2023)
Abstract Breast cancer bone metastasis has become a common cancer type that still lacks an effective treatment method. Although epigenetic drugs have demonstrated promise in cancer therapy, their nontargeted accumulation and drug resistance remain no
Externí odkaz:
https://doaj.org/article/9b3f77cd9a714fe29b7a6cc41f13b4a1
Autor:
Chuan Hu, Yujun Song, Yiwei Zhang, Siqin He, Xueying Liu, Xiaotong Yang, Tao Gong, Yuan Huang, Huile Gao
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 5, Pp 2176-2187 (2023)
Intelligent responsive drug delivery system opens up new avenues for realizing safer and more effective combination immunotherapy. Herein, a kind of tumor cascade-targeted responsive liposome (NLG919@Lip-pep1) is developed by conjugating polypeptide
Externí odkaz:
https://doaj.org/article/775134a50507410ba661548319733cdb
Publikováno v:
Advanced Science, Vol 11, Iss 1, Pp n/a-n/a (2024)
Abstract Cancer immunotherapy using anti‐programmed death‐ligand 1 (PD‐L1) antibodies has been used in various clinical applications and achieved certain results. However, such limitations as autoimmunity, tumor hyperprogression, and overall lo
Externí odkaz:
https://doaj.org/article/a79a0c57761449dba37540cdf91eb938
Publikováno v:
Advanced NanoBiomed Research, Vol 3, Iss 12, Pp n/a-n/a (2023)
The therapeutic modes of cancers have been profoundly renovated by immunotherapies, which have shown extraordinary treating efficacy in certain tumor entities. However, the majority of cancer patients have not profited from it because of the negative
Externí odkaz:
https://doaj.org/article/015a76989c7647f0ae4fabab830ea398