Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Huilan Lin"'
Autor:
Xiaoxi Li, Yaxin Yao, Dunmei Zhao, Xiufeng Chang, Yi Li, Huilan Lin, Huijuan Wei, Haiye Wang, Ying Mi, Lei Huang, Sijia Lu, Weimin Yang, Liyi Cai
Publikováno v:
Reproductive Biology and Endocrinology, Vol 22, Iss 1, Pp 1-9 (2024)
Abstract Background Prospective observational studies have demonstrated that the machine learning (ML) -guided noninvasive chromosome screening (NICS) grading system, which we called the noninvasive chromosome screening-artificial intelligence (NICS-
Externí odkaz:
https://doaj.org/article/8c943c21bd034056bfbc6828d80be8de
Publikováno v:
Sensors, Vol 24, Iss 6, p 1778 (2024)
Infrared video target detection is a fundamental technology within infrared warning and tracking systems. In long-distance infrared remote sensing images, targets often manifest as circular spots or even single points. Due to the weak and similar cha
Externí odkaz:
https://doaj.org/article/46312a6205fc44c482cd14639d78a74c
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
Scientific Reports
Scientific Reports
Most lysosomal storage disorders affect the central nervous system. However, lysosomal enzymes do not cross the blood-brain barrier (BBB), and intravenous enzyme infusion is not effective for the brain. Lysosomal enzymes can be re-engineered for BBB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43a8de8f860598c92da033df5d41efba
http://link.springer.com/article/10.1038/s41598-019-55136-4
http://link.springer.com/article/10.1038/s41598-019-55136-4
Autor:
Luisa J. Coronel, Hemal H. Patel, Neil Grimsey, Cisneros-Aguirre M, Mark A. Lawson, Olivia Molinar-Inglis, Anand Patwardhan, Gomez-Menzies Pk, JoAnn Trejo, Dequina A. Nicholas, Cierra A. Birch, Huilan Lin, Brian H. Chen
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 118, iss 49
Proc Natl Acad Sci U S A
Proc Natl Acad Sci U S A
Endothelial dysfunction is associated with vascular disease and results in disruption of endothelial barrier function and increased sensitivity to apoptosis. Currently, there are limited treatments for improving endothelial dysfunction. Activated pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b3087ad0fccc2054ddfb4ef55a58eef
https://doi.org/10.1073/pnas.2106623118
https://doi.org/10.1073/pnas.2106623118
Autor:
Molinar-Inglis, Olivia, Birch, Cierra A., Nicholas, Dequina, Orduña-Castillo, Lennis, Cisneros-Aguirre, Metztli, Patwardhan, Anand, Buxin Chen, Grimsey, Neil J., Coronel, Luisa J., Huilan Lin, Menzies, Patrick K. Gomez, Lawson, Mark A., Patel, Hemal. H., Trejo, JoAnn
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 12/7/2021, Vol. 118 Issue 49, p1-11, 11p
Publikováno v:
Molecular Biology of the Cell
Molecular biology of the cell, vol 26, iss 25
Molecular biology of the cell, vol 26, iss 25
The novel ALIX-dependent GPCR sorting pathway is regulated by the a-arrestin ARRDC3. A critical role is also shown for the E3 ubiquitin ligase WWP2 in regulation of ALIX ubiquitination and lysosomal sorting of GPCRs.
The sorting of G protein–c
The sorting of G protein–c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b7c4ff561c2c79fba02e335299e444d
https://doi.org/10.1091/mbc.e15-05-0284
https://doi.org/10.1091/mbc.e15-05-0284
Publikováno v:
The Journal of biological chemistry, vol 293, iss 9
Aberrant G protein-coupled receptor (GPCR) expression and activation has been linked to tumor initiation, progression, invasion, and metastasis. However, compared with other cancer drivers, the exploitation of GPCRs as potential therapeutic targets h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13f1cc72fdafd579aa56dc0a517ebc6b
https://escholarship.org/uc/item/97p5t6w4
https://escholarship.org/uc/item/97p5t6w4
Publikováno v:
Molecular Genetics and Metabolism. 126:S114-S115
Batten disease has primary brain manifestations. Progress in the treatment has primarily been limited to the fact that recombinant enzymes are large molecules that do not cross the blood-brain barrier (BBB). BBB-penetration of enzyme therapeutics is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::98895d4f57005b3c0fa45af281d1349f
https://doi.org/10.1016/j.ymgme.2018.12.291
https://doi.org/10.1016/j.ymgme.2018.12.291
Publikováno v:
Molecular Genetics and Metabolism. 126:S95-S96
The majority of lysosomal storage disorders (LSD) affect the brain. Intravenous enzyme replacement therapy does not treat the brain, because recombinant enzymes are large molecules that do not cross the blood-brain barrier (BBB). BBB-penetration of e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69226b2535e09a4c7a5689ddf04334a6
https://doi.org/10.1016/j.ymgme.2018.12.238
https://doi.org/10.1016/j.ymgme.2018.12.238
Publikováno v:
Molecular Genetics and Metabolism. 126:S32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::752a4edd12eaf4cce69e429845a34ab7
https://doi.org/10.1016/j.ymgme.2018.12.060
https://doi.org/10.1016/j.ymgme.2018.12.060