Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Huilan Gao"'
Autor:
Qianqian Xu, Huilan Gao, Fuqiang Zhu, Wenliang Xu, Yubo Wang, Jinwen Xie, Guangjun Guo, Limei Yang, Li Ma, Zhiqiang Shen, Jichang Li
Publikováno v:
International Journal of Analytical Chemistry, Vol 2024 (2024)
Traditional Chinese medicine (TCM) serves as a significant adjunct to chemical treatment for chronic diseases. For instance, the administration of Baitouweng decoction (BTWD) has proven effective in the treatment of ulcerative colitis. However, the l
Externí odkaz:
https://doaj.org/article/f6354920ee1a42219135576c37495560
Autor:
Robert Martinez, Michael Shamashkin, Bryan T. MacDonald, Xinjun Zhang, Anthony J. Coyle, Huilan Gao, Xi He
Publikováno v:
Journal of Biological Chemistry. 295:1367-1367
The Wnt family of secreted glycolipoproteins plays pivotal roles in development and human diseases. Tiki family proteins were identified as novel Wnt inhibitors that act by cleaving the Wnt amino-terminal region to inactivate specific Wnt ligands. Ti
Autor:
Joanne Brodfuehrer, Tatyana Andreyeva, Julie Lee, Wenyan Miao, Khetemenee Lam, Jameel Syed, Rosemary Lawrence-Henderson, Josef S. Ozer, Jason Edmonds, Andrew L. Rankin, Angela Boisvert, Sean Keegan, Huilan Gao, Pratap Singh, Timothy P. LaBranche, Laird Bloom
Publikováno v:
Pharmaceutical Research. 31:635-648
Study the impact of CXCL13 neutralization on germinal center (GC) response in vivo, and build quantitative relationship between target coverage and pharmacological effects at the target tissue. An anti-CXCL13 neutralizing monoclonal antibody was dose
Autor:
Bryan T. MacDonald, Xi He, Huilan Gao, Robert V. Martinez, Michael Shamashkin, Anthony J. Coyle, Xinjun Zhang
Publikováno v:
The Journal of biological chemistry. 291(5)
The Wnt family of secreted glycolipoproteins plays pivotal roles in development and human diseases. Tiki family proteins were identified as novel Wnt inhibitors that act by cleaving the Wnt amino-terminal region to inactivate specific Wnt ligands. Ti
The functional repertoire of rabbit antibodies and antibody discovery via next-generation sequencing
Autor:
Snehal Naik, Christine Huard, Juan Carlos Almagro, Kodangattil Sreekumar R, Huilan Gao, Santosh Hodawadekar, Jian Li, Cindy Ross, Alberto Visintin, Jessica Min-debartolo, Alessandro Mascioni
To gain insight into the functional antibody repertoire of rabbits, the VH and VL repertoires of bone marrow (BM) and spleen (SP) of a naive New Zealand White rabbit (NZW; Oryctolagus cuniculus) and that of lymphocytes collected from a NZW rabbit imm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b152e658fa3b096130d5692e913eb0f
https://europepmc.org/articles/PMC4011907/
https://europepmc.org/articles/PMC4011907/
Autor:
Laura F. Gibson, Joseph P. Lynch, Solveig G. Ericson, Yue Zhao, Huilan Gao, Kathryn L. Miller, Kenneth S. Landreth
Publikováno v:
Blood. 91:2099-2107
Polymorphonuclear neutrophils (PMNs) are essential effector cells in host defense and tissue inflammatory responses. These responses may be initiated after cross-linking of cell surface Fc receptors that bind the constant portion of IgG (FcγR). We e
Autor:
Deirdre Ní Shúilleabháin, John Steven, Elizabeth Kieras, Amy Tam, Matthew J. Whitters, Laird Bloom, Huilan Gao, Matthew McKenna, Brian J. Fennell, Lijun Chang, Orla Cunningham, Allan Jensen, Wenyan Miao, Mark R. H. Krebs, William J.J. Finlay, Alfredo Darmanin-Sheehan, Amy King, Janet E. Paulsen, Deborah Luxenberg, Lori Fitz, Yongjing J Guo, C.M. Francis, William S. Somers, Jason Edmonds, Laura Lin, Christopher Grace, Ian D. Broadbent, Timothy P. Hickling, Angela Boisvert, Barry McDonnell, Emma Cummins, Xiaotian Zhong, Jennifer Alley, Quintus G. Medley, Stephane Olland, Bénédicte Autin
Publikováno v:
mAbs
While myriad molecular formats for bispecific antibodies have been examined to date, the simplest structures are often based on the scFv. Issues with stability and manufacturability in scFv-based bispecific molecules, however, have been a significant
Autor:
Wenyan Miao, Jennifer Alley, Gabriel Berstein, Marion Kasaian, Huilan Gao, Laird Bloom, James D. Clark
Publikováno v:
Assay and drug development technologies. 8(1)
The chemokine receptor CXCR5 is predominantly expressed on mature B cells and follicular T-helper cells. CXCR5 and its ligand CXCL13 participate in ectopic germinal center formation at the inflammatory sites of multiple immune diseases such as rheuma
Autor:
David, Tovo, Yun Cheol Kim, Ely, Lauren K., Rondon, Isaac, Huilan Gao, O’Brien, Peter, Bolt, Michael W., Coyle, Anthony J., Garcia, Jorge L., Flounders, Eric A., Mikita, Thomas, Coughlin, Shaun R.
Publikováno v:
Science Translational Medicine; 8/24/2016, Vol. 8 Issue 353, p1-14, 14p, 2 Charts, 7 Graphs
Publikováno v:
Cancer letters. 112(1)
Mining and mineral processing are important industries in the United States. A large number of workers are potentially exposed to silica during mining and to glass fibers during manufacturing. There is a concern regarding lung cancer risk among worke