Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Huijun Zhong"'
Autor:
Yinghua Wei, Jin Li, Ruhong Xu, Li Wen, Yiming Deng, Lixia He, Huijun Zhong, Yanhao Wang, Yanjie Yin
Publikováno v:
Chinese Medical Journal, Vol 136, Iss 22, Pp 2677-2685 (2023)
Abstract. Background:. Dual regimen dolutegravir (DTG) plus lamivudine (3TC) has demonstrated non-inferior efficacy compared to DTG-based three-drug regimens (3DRs), yet directly comparative data regarding the efficacy and safety of DTG + 3TC and bic
Externí odkaz:
https://doaj.org/article/136e409bcae9423194e4a13d5d9ee122
Autor:
Jin Li, Dabiao Chen, Zhiwei Wen, Yanzhang Du, Zhanlian Huang, Huijun Zhong, Yanhao Wang, Sichun Yin
Publikováno v:
Medicine. 101(42)
Limited real-world data on dolutegravir (DTG) plus lamivudine (3TC) for HIV-1-infected individuals have been reported. This study aimed to evaluated the real-world efficacy and safety of DTG + 3TC in ART-naïve HIV-1-infected adults in China. This re
Publikováno v:
Genetic testing and molecular biomarkers. 24(1)
Background: Heroin use disorder (HUD) is a complex brain disease that includes multiple phenotypes. Heroin acts primarily as a mu-opioid receptor (OPRM1) agonist. The κ opioid receptor 1 (OPRK1) is...
Publikováno v:
The Journal of Physiology. 587:329-344
GABA is expressed in carotid body (CB) chemoreceptor type I cells and has previously been reported to modulate sensory transmission via presynaptic GABAB receptors. Because low doses of clinically important GABAA receptor (GABAAR) agonists, e.g. benz
Publikováno v:
Anesthesiology. 108:103-112
γ-AMINOBUTYRIC acid type A (GABAA) receptors are the major inhibitory neurotransmitter system in the brain and important targets for many neuromodulatory drugs, including sedatives, antiepileptics, neuro-active steroids, and general anesthetics. Eac
Publikováno v:
The Journal of Physiology. 551:825-842
The peripheral control of breathing is mediated by O2-sensitive carotid body (CB) type 1 cells, which express multiple neurotransmitters including the monoamines, dopamine and serotonin (5-HT). Whereas dopamine has been extensively studied, 5-HT has
Publikováno v:
Proceedings of the National Academy of Sciences. 98:4705-4709
N-type Ca 2+ channels can be inhibited by neurotransmitter-induced release of G protein βγ subunits. Two isoforms of Ca v 2.2 α1 subunits of N-type calcium channels from rat brain (Ca v 2.2a and Ca v 2.2b; initially termed rbB-I and rbB-II) have d
Publikováno v:
Proceedings of the National Academy of Sciences. 98:4699-4704
N-type and P/Q-type Ca 2+ channels are inhibited by neurotransmitters acting through G protein-coupled receptors in a membrane-delimited pathway involving Gβγ subunits. Inhibition is caused by a shift from an easily activated “willing” ( W ) st
Autor:
Colin A. Nurse, Huijun Zhong
Publikováno v:
Brain Research. 766:153-161
Using whole-cell, patch-clamp techniques we investigated acetylcholine (ACh) sensitivity of dissociated sensory neurons from rat petrosal ganglia after 4 h-14 days in vitro. In approx. 68% of petrosal neurons (PN; n = 109) ACh, applied by fast perfus
Autor:
Colin A. Nurse, Huijun Zhong
Publikováno v:
Primary Sensory Neuron. 2:95-110
Regulation of carotid body chemoafferent discharge in mammals plays an important role in the reflex control of ventilation. A non-selective blocker (cesium) of the inward rectifier is known to inhibit carotid body afferent discharge during hypoxia, b