Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Huihuan Wu"'
Autor:
Ruijie Zeng, Yuying Ma, Lijun Zhang, Dongling Luo, Rui Jiang, Huihuan Wu, Zewei Zhuo, Qi Yang, Jingwei Li, Felix W Leung, Chongyang Duan, Weihong Sha, Hao Chen
Publikováno v:
eLife, Vol 13 (2024)
Background: Adverse effects of proton pump inhibitors (PPIs) have raised wide concerns. The association of PPIs with influenza is unexplored, while that with pneumonia or COVID-19 remains controversial. Our study aims to evaluate whether PPI use incr
Externí odkaz:
https://doaj.org/article/03f60e249a1a4e02b3295266f0b80ea9
Autor:
Qi Yang, Zewei Zhuo, Xinqi Qiu, Ruibang Luo, Kehang Guo, Huihuan Wu, Rui Jiang, Jingwei Li, Qizhou Lian, Pengfei Chen, Weihong Sha, Hao Chen
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-21 (2024)
Abstract Background Emerging evidence suggests that Rho GTPases play a crucial role in tumorigenesis and metastasis, but their involvement in the tumor microenvironment (TME) and prognosis of hepatocellular carcinoma (HCC) is not well understood. Met
Externí odkaz:
https://doaj.org/article/8f7cd50b682f4f79babd62160f60771a
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
Background:Recently, observational studies have reported that gastroesophageal reflux disease (GERD) is commonly associated with irritable bowel syndrome (IBS), but the causal relationship is unclear.Methods:We conducted a two-sample Mendelian random
Externí odkaz:
https://doaj.org/article/58f76b07937c455b8f1e521988a11836
Publikováno v:
Biomedicines, Vol 12, Iss 5, p 989 (2024)
Inflammatory bowel diseases (IBD) are chronic inflammatory disorders affecting the digestive tract, including ulcerative colitis and Crohn’s disease. Ruscogenin, a prominent steroidal sapogenin present in radix ophiopogon japonicus, has shown a pro
Externí odkaz:
https://doaj.org/article/9dd7b926f42d4b1cb882075335d50f6d
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Toripalimab, a specific immune checkpoint inhibitor targeting the programmed death 1 (PD-1) receptor, represents a novel immunotherapeutic approach for advanced nasopharyngeal carcinoma, showing promising curative potential. However, it is not withou
Externí odkaz:
https://doaj.org/article/d52f3f0a36de448b953053a9cd1262b7
Autor:
Jinghua Wang, Xinqi Qiu, Jiayu Huang, Zewei Zhuo, Hao Chen, Ruijie Zeng, Huihuan Wu, Kehang Guo, Qi Yang, Huiling Ye, Wei Huang, Yujun Luo
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-14 (2022)
Abstract Background Glioblastoma multiforme (GBM) is one of the most malignant tumors in brain with high morbidity and mortality. Mitophagy plays a significant role in carcinogenesis, metastasis, and invasion. In our study, we aim to construct a mito
Externí odkaz:
https://doaj.org/article/b619c48c98224aff8f3583ebcb5103d9
Autor:
Huihuan Wu, Ruijie Zeng, Xinqi Qiu, Kequan Chen, Zewei Zhuo, Kehang Guo, Yawen Xiang, Qi Yang, Rui Jiang, Felix W. Leung, Qizhou Lian, Weihong Sha, Hao Chen
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
IntroductionCrohn’s disease is characterized of dysregulated inflammatory and immune reactions. The role of the NOD-like receptor family, pyrin domain-containing 3 (NLRP3) inflammasome in Crohn’s disease remains largely unknown.MethodsThe microar
Externí odkaz:
https://doaj.org/article/a2c95ac5691f4d129a6766a6507b0b68
Autor:
Hao Chen, Rui Jiang, Wentao Huang, Kequan Chen, Ruijie Zeng, Huihuan Wu, Qi Yang, Kehang Guo, Jingwei Li, Rui Wei, Songyan Liao, Hung-Fat Tse, Weihong Sha, Zewei Zhuo
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
ObjectiveEnergy metabolism plays a crucial role in the improvement of heart dysfunction as well as the development of heart failure (HF). The current study is designed to identify energy metabolism-related diagnostic biomarkers for predicting the ris
Externí odkaz:
https://doaj.org/article/abd9a8e83c1948ada3adef49f8768f70
Publikováno v:
IET Renewable Power Generation, Vol 15, Iss 9, Pp 1996-2006 (2021)
Abstract This study proposes a novel power supply system that utilises wind power to produce AC and DC power. A special designed generator based on bidirectional flux modulation effect is the key part of the proposed power supply system. The novel po
Externí odkaz:
https://doaj.org/article/e9777c5568f54b9396460e218fd96502
Autor:
Huihuan Wu, Kehang Guo, Zewei Zhuo, Ruijie Zeng, Yujun Luo, Qi Yang, Jingwei Li, Rui Jiang, Zena Huang, Weihong Sha, Hao Chen
Publikováno v:
Frontiers in Pediatrics, Vol 10 (2022)
Necrotizing enterocolitis (NEC) is one of the most prevalent neonatal gastrointestinal disorders. Despite ongoing breakthroughs in its treatment and prevention, the incidence and mortality associated with NEC remain high. New therapeutic approaches,
Externí odkaz:
https://doaj.org/article/188c8eb417b84e1787324b1b90b8afdd