Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Huihao Zhou"'
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-13 (2024)
Abstract Endometrial cancer (EC), as one of the most common cancers, severely threatens female reproductive health. Our previous study has shown that Kinesin family member C1 (KIFC1) played crucial roles in the progression of EC. In addition, abnorma
Externí odkaz:
https://doaj.org/article/78d72e995dad40fe8e125a26423d676e
Publikováno v:
Journal of Cannabis Research, Vol 5, Iss 1, Pp 1-8 (2023)
Abstract Objective Although the chemical constituents of the aerial parts of Cannabis have been extensively studied, phytochemicals of Cannabis roots are not well characterized. Herein, we investigated the chemical constituents of industrial hemp (Ca
Externí odkaz:
https://doaj.org/article/e1dab2fef2164585b75a22329a3e9e33
Autor:
Dane Huang, Chao Zhao, Ruyue Li, Bingyi Chen, Yuting Zhang, Zhejun Sun, Junkang Wei, Huihao Zhou, Qiong Gu, Jun Xu
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Huang et al. discover a binding site on soluble RANKL that is not found on its membrane-bound homologue. A drug screening identified a small molecule (S3-15) that can target this binding site and has anti-osteoporotic but not immunosuppressive effect
Externí odkaz:
https://doaj.org/article/72ed5536113e4557af499911ac1cabd6
Publikováno v:
ACS Central Science, Vol 7, Iss 6, Pp 980-989 (2021)
Externí odkaz:
https://doaj.org/article/dd0edc10c18643ca96326140a01b1f2b
Autor:
Baisen Zhong, Weiyu Peng, Shan Du, Bingyi Chen, Yajuan Feng, Xinfeng Hu, Qi Lai, Shujie Liu, Zhong-Wei Zhou, Pengfei Fang, Yan Wu, Feng Gao, Huihao Zhou, Litao Sun
Publikováno v:
Small Science, Vol 2, Iss 6, Pp n/a-n/a (2022)
The current COVID‐19 pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), is an enormous threat to public health. The SARS‐CoV‐2 3C‐like protease (3CLpro), which is critical for viral replication and transcrip
Externí odkaz:
https://doaj.org/article/6dc5c8801004499b86b77fc988af8897
Autor:
Bingyi Chen, Siting Luo, Songxuan Zhang, Yingchen Ju, Qiong Gu, Jun Xu, Xiang-Lei Yang, Huihao Zhou
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Reveromycin A (RM-A) selectively inhibits eukaryotic cytoplasmic isoleucyltRNA synthetase (IleRS). Herein, the authors show that RM-A molecule occupies the tRNAIle binding site of Saccharomyces cerevisiae IleRS, and that RM-A cooperates with isoleuci
Externí odkaz:
https://doaj.org/article/aa106fd7577240a4b8e1ff9e7d96b4fa
Autor:
Hongjiao Xu, Qian Zhao, Nazi Song, Zhibin Yan, Runfeng Lin, Shuohan Wu, Lili Jiang, Sihua Hong, Junqiu Xie, Huihao Zhou, Rui Wang, Xianxing Jiang
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Nonalcoholic steatohepatitis (NASH) and associated liver fibrosis have limited therapy options. Here the authors report a novel adiponectin-based dual agonist for adiponectin receptors 1 and 2 with a longer half-life, and show that it ameliorates NAS
Externí odkaz:
https://doaj.org/article/14a1b270a4d24c8f81f31ac78a992843
Autor:
Youngzee Song, Huihao Zhou, My-Nuong Vo, Yi Shi, Mir Hussain Nawaz, Oscar Vargas-Rodriguez, Jolene K. Diedrich, John R. Yates, Shuji Kishi, Karin Musier-Forsyth, Paul Schimmel
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
Non-proteinogenic (np) amino acids in the food chain present challenges for the human translation machinery. Here the authors show that, while AlaRS and ProRS activate toxic np azetidine-2-carboxylic acid (Aze) present in sugar beets and lilies, only
Externí odkaz:
https://doaj.org/article/ab6942f80cab4c61b84fff08d09c316d
Autor:
Hongjiao Xu, Qian Zhao, Nazi Song, Zhibin Yan, Runfeng Lin, Shuohan Wu, Lili Jiang, Sihua Hong, Junqiu Xie, Huihao Zhou, Rui Wang, Xianxing Jiang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-2 (2021)
A Correction to this paper has been published: https://doi.org/10.1038/s41467-021-22414-7
Externí odkaz:
https://doaj.org/article/7a99a013399741a28209890b43f6e53a
Autor:
Yingchen Ju, Zhihong Liu, Zizhen Zhang, Lijun Duan, Qi Liu, Qiong Gu, Cheng Zhang, Jun Xu, Huihao Zhou
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Proteus vulgaris L-amino acid deaminase (pvLAAD) belongs to a class of bacterial membrane-bound LAADs mainly express in genus Proteus, Providencia and Morganella. These LAADs employ a non-cleavable N-terminal twin-arginine translocation (Tat
Externí odkaz:
https://doaj.org/article/55f8714b74614c219b16497882f9381b