Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Huifeng Pi"'
Autor:
Qinlong Ma, Zhiqi Yang, Chuanyan Yang, Min Lin, Mingyue Gong, Ping Deng, Mindi He, Yonghui Lu, Kuan Zhang, Huifeng Pi, Mingyue Qu, Zhengping Yu, Zhou Zhou, Chunhai Chen
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-16 (2024)
Abstract The effects of neurotoxicant cadmium (Cd) exposure on brain development have not been well elucidated. To investigate this, we have herein subjected pregnant mice to low-dose Cd throughout gestation. Using single-cell RNA sequencing (scRNA-s
Externí odkaz:
https://doaj.org/article/3469b2ff55e4449a8e63fa3f5371f148
Autor:
Ping Deng, Tengfei Fan, Peng Gao, Yongchun Peng, Min Li, Jingdian Li, Mingke Qin, Rongrong Hao, Liting Wang, Lei Zhang, Chunhai Chen, Mindi He, Yonghui Lu, Qinlong Ma, Yan Luo, Li Tian, Jia Xie, Mengyan Chen, Shangcheng Xu, Zhou Zhou, Zhengping Yu, Huifeng Pi
Publikováno v:
Advanced Science, Vol 11, Iss 30, Pp n/a-n/a (2024)
Abstract Cadmium (Cd) is a neurotoxic contaminant that induces cognitive decline similar to that observed in Alzheimer's disease (AD). Autophagic flux dysfunction is attributed to the pathogenesis of AD, and this study aimed to investigate the effect
Externí odkaz:
https://doaj.org/article/60b23ab475fc491b9116ab484fec3ef5
Autor:
Xiqin Lin, Yudong Xu, Tong Tong, Jingjing Zhang, Haotian He, Lingling Yang, Ping Deng, Zhengping Yu, Huifeng Pi, Huihui Hong, Zhou Zhou
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 265, Iss , Pp 115517- (2023)
Cadmium is a highly ubiquitous environmental pollutant that poses a serious threat to human health. In this study, we assessed the cardiotoxicity of Cd exposure and explored the possible mechanisms by which Cd exerts its toxic effects. The results de
Externí odkaz:
https://doaj.org/article/19d1a85e35d6434d9860a19026b0fb08
Autor:
Muxue Lu, Ping Deng, Lingling Yang, Xue Wang, Xiang Mei, Chao Zhou, Mengyan Chen, Zhou Zhou, Huifeng Pi, Lichuan Wu, Zhengping Yu
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 263, Iss , Pp 115238- (2023)
Although adequate intake of manganese (Mn) is essential to humans, Mn in excess is neurotoxic. Exposure to extremely high doses of Mn results in “manganism”, a condition that exhibits Parkinson-like symptoms. However, the mechanisms underlying it
Externí odkaz:
https://doaj.org/article/18fcd68ecbcf4d00b76c34c26cdfa05a
Autor:
Tong Tong, Weixia Duan, Yudong Xu, Huihui Hong, Jia Xu, Guanyan Fu, Xue Wang, Lingling Yang, Ping Deng, Jingjing Zhang, Haotian He, Gaofeng Mao, Yuanqiang Lu, Xiqin Lin, Zhengping Yu, Huifeng Pi, Yong Cheng, Shangcheng Xu, Zhou Zhou
Publikováno v:
Environment International, Vol 178, Iss , Pp 108063- (2023)
Externí odkaz:
https://doaj.org/article/10d273f780484650a7c4ca17d49de15d
Autor:
Xin Tan, Rongyi Zhang, Meide Lan, Cong Wen, Hao Wang, Junsong Guo, Xuemei Zhao, Hui Xu, Ping Deng, Huifeng Pi, Zhengping Yu, Rongchuan Yue, Houxiang Hu
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 162, Iss , Pp 114733- (2023)
Doxorubicin (DOX) is an anthracycline antineoplastic agent that has limited clinical utility due to its dose-dependent cardiotoxicity. Although the exact mechanism remains unknown, inflammatory responses have been implicated in DOX-induced cardiotoxi
Externí odkaz:
https://doaj.org/article/6257918c4caa4f7f8a297cfb11ad1ada
Autor:
Tengfei Fan, Xiaoning Wang, Sheng Zhang, Ping Deng, Yi Jiang, Yidan Liang, Sheng Jie, Qing Wang, Chuwen Li, Guocai Tian, Zhen Zhang, Zhenhu Ren, Bo Li, Yanrong Chen, Zhijing He, Yan Luo, Mingliang Chen, Hanjiang Wu, Zhengping Yu, Huifeng Pi, Zhou Zhou, Zhiyuan Zhang
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 7, Iss 1, Pp 1-11 (2022)
Abstract Oral squamous cell carcinoma (OSCC) is the most common type of oral malignancy, and metastasis accounts for the poor prognosis of OSCC. Autophagy is considered to facilitate OSCC development by mitigating various cellular stresses; neverthel
Externí odkaz:
https://doaj.org/article/d28f7cdea6d349c7b485c79d7d520f94
Publikováno v:
Frontiers in Physiology, Vol 13 (2023)
Externí odkaz:
https://doaj.org/article/183f17b0f8f3429bb7773ee8607257f0
Autor:
Yang Yue, Miduo Tan, Yan Luo, Ping Deng, Hui Wang, Jingdian Li, Rongrong Hao, Li Tian, Jia Xie, Mengyan Chen, Zhengping Yu, Zhou Zhou, Huifeng Pi
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 247, Iss , Pp 114270- (2022)
Cadmium (Cd), which is considered an endocrine disruptor, has been linked to the onset of breast cancer (BC). Our recent study demonstrated that Cd-induced BC progression has a strong correlation with miR-374c-5p dysregulation. The aim of our work wa
Externí odkaz:
https://doaj.org/article/af289476985742d3841a973654bacc46
Autor:
Tong Tong, Weixia Duan, Yudong Xu, Huihui Hong, Jia Xu, Guanyan Fu, Xue Wang, Lingling Yang, Ping Deng, Jingjing Zhang, Haotian He, Gaofeng Mao, Yuanqiang Lu, Xiqin Lin, Zhengping Yu, Huifeng Pi, Yong Cheng, Shangcheng Xu, Zhou Zhou
Publikováno v:
Environment International, Vol 169, Iss , Pp 107512- (2022)
Paraquat (PQ) is the most widely used herbicide in the world and a well-known potent neurotoxin for humans. PQ exposure has been linked to increase the risk of Parkinson's disease (PD). However, the mechanism underlying its neurotoxic effects in PD p
Externí odkaz:
https://doaj.org/article/ec2a1584a57540609a36150bffae461f