Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Huifang Xian"'
Autor:
Ming Liu, Bingtai Lu, Yue Li, Shuofeng Yuan, Zhen Zhuang, Guangyu Li, Dong Wang, Liuheyi Ma, Jianheng Zhu, Jinglu Zhao, Chris Chung-Sing Chan, Vincent Kwok-Man Poon, Kenn Ka-Heng Chik, Zhiyao Zhao, Huifang Xian, Jingxian Zhao, Jincun Zhao, Jasper Fuk-Woo Chan, Yuxia Zhang
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-15 (2023)
Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), has had a significant impact on healthcare systems and economies worldwide. The continuous emergence of new viral strai
Externí odkaz:
https://doaj.org/article/c02112b836a14ac28ad39f3d5eb26d75
Autor:
Xiaoyan Liu, Zhe Li, Shuai Liu, Jing Sun, Zhanghua Chen, Min Jiang, Qingling Zhang, Yinghua Wei, Xin Wang, Yi-You Huang, Yinyi Shi, Yanhui Xu, Huifang Xian, Fan Bai, Changxing Ou, Bei Xiong, Andrew M. Lew, Jun Cui, Rongli Fang, Hui Huang, Jincun Zhao, Xuechuan Hong, Yuxia Zhang, Fuling Zhou, Hai-Bin Luo
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 10, Iss 7, Pp 1205-1215 (2020)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection can cause acute respiratory distress syndrome, hypercoagulability, hypertension, and multiorgan dysfunction. Effective antivirals with safe clinical profile are urgently needed to
Externí odkaz:
https://doaj.org/article/961d6c2809cb41e197a7c2eddff405db
Auto-ubiquitination of NEDD4-1 Recruits USP13 to Facilitate Autophagy through Deubiquitinating VPS34
Autor:
Weihong Xie, Shouheng Jin, Yaoxing Wu, Huifang Xian, Shuo Tian, Di-Ao Liu, Zhiyong Guo, Jun Cui
Publikováno v:
Cell Reports, Vol 30, Iss 8, Pp 2807-2819.e4 (2020)
Summary: The class III phosphoinositide 3-kinase vacuolar protein sorting 34 (VPS34) is a core protein of autophagy initiation, yet the regulatory mechanisms responsible for its stringent control remain poorly understood. Here, we report that the E3
Externí odkaz:
https://doaj.org/article/a8e8e6b0b56e47e6ad63cc2576a1ed2a
Autor:
Yanyan Zheng, Liqiu Wang, Qingxiang Liu, Huifang Xian, Chenqiu Zhang, Sihui Cai, Shuai Yang, Shouheng Jin, Jun Cui
Publikováno v:
Nature Microbiology. 8:958-972
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16fb163700f5b30dd95b6a36575a21f1
https://doi.org/10.1038/s41564-023-01357-3
https://doi.org/10.1038/s41564-023-01357-3
Autor:
Tingzhe Sun, Jun Wang, Shuai Yang, Chuanxia Zhang, Huifang Xian, Jun Cui, Wanming Huang, Yuxia Zhang
Publikováno v:
Science Bulletin. 66:794-802
Ubiquitination plays a crucial role in retinoic acid-inducible gene I (RIG-I)-induced antiviral responses. However, the precise regulatory mechanisms of RIG-I activity mediated by conjugated and unanchored ubiquitin chains remain to be determined. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ef59c29ce81a59b8f85071405cf9b58
https://doi.org/10.1016/j.scib.2020.11.003
https://doi.org/10.1016/j.scib.2020.11.003
Autor:
Shuai Yang, Shouheng Jin, Huifang Xian, Zhiyao Zhao, Liqiu Wang, Yaoxing Wu, Liang Zhou, Mengqiu Li, Jun Cui
Publikováno v:
Molecular cell.
Post-translational modifications (PTMs) of proteins are crucial to guarantee the proper biological functions in immune responses. Although protein phosphorylation has been extensively studied, our current knowledge of protein pyrophosphorylation, whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0772d96304ae8116c3119308c8193541
https://pubmed.ncbi.nlm.nih.gov/36603579
https://pubmed.ncbi.nlm.nih.gov/36603579
Autor:
Zhe Li, Qingling Zhang, Yinghua Wei, Yanhui Xu, Zhanghua Chen, Andrew M. Lew, Jun Cui, Hui Huang, Fan Bai, Changxing Ou, Min Jiang, Fuling Zhou, Jincun Zhao, Jing Sun, Yi-You Huang, Xuechuan Hong, Huifang Xian, Rongli Fang, Xiaoyan Liu, Yuxia Zhang, Hai-Bin Luo, Bei Xiong, Yinyi Shi, Xin Wang, Shuai Liu
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 10, Iss 7, Pp 1205-1215 (2020)
Acta Pharmaceutica Sinica B
Acta pharmaceutica Sinica, 10(7):1205-1215
Acta Pharmaceutica Sinica B
Acta pharmaceutica Sinica, 10(7):1205-1215
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection can cause acute respiratory distress syndrome, hypercoagulability, hypertension, and multiorgan dysfunction. Effective antivirals with safe clinical profile are urgently needed to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4da722940333c034dfb6b87db2b4a4bd
https://doi.org/10.1016/j.apsb.2020.04.008
https://doi.org/10.1016/j.apsb.2020.04.008
Autor:
Tong Zhang, Yiping Xu, Chengwei Chai, Shuhong Yi, Zhe Wen, Huiying Liang, Meixue Zhang, Yan Zhang, Zhuang-gui Chen, Liwei Lu, Yanlu Tong, Bingtai Lu, Zefeng Lin, David Delfouneso, Stephen L. Nutt, Xiaoqiong Gu, Junli Nie, Yuxia Zhang, Liang Zeng, Huimin Xia, Jiankun Liang, Shanmeizi Zhao, Li Zhang, Yanhui Xu, Jixiao Zeng, Qi Wu, Andrew M. Lew, Fan Bai, Jun Wang, Xiaohui Wang, Bing Huang, Huifang Xian, Qiang Wu, Zhanghua Chen, Yuzhen Lin, Xuanjie Guo
Publikováno v:
Cell. 183(7)
Biliary atresia (BA) is a severe cholangiopathy that leads to liver failure in infants, but its pathogenesis remains to be fully characterized. By single-cell RNA profiling, we observed macrophage hypo-inflammation, Kupffer cell scavenger function de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcb62dc7897ff826f80cdf5b5dd27fcd
https://pubmed.ncbi.nlm.nih.gov/35590128
https://pubmed.ncbi.nlm.nih.gov/35590128
Autor:
Hui Huang, Jing Sun, Jun Cui, Yinyi Shi, Jincun Zhao, Yanhui Xu, Zhanghua Chen, Xiaoyan Liu, Shuai Liu, Bei Xiong, Huifang Xian, Yi-You Huang, Hai-Bin Luo, Zhiyao Zhao, Fulin Zhou, Andrew M. Lew, Jun Wang, Yuxia Zhang, Zhe Li, Qingling Zhang, Fan Bai, Rongli Fang, Xuechuan Hong, Changxing Ou
The human coronavirus HCoV-19 infection can cause acute respiratory distress syndrome (ARDS), hypercoagulability, hypertension, extrapulmonary multiorgan dysfunction. Effective antiviral and anti-coagulation agents with safe clinical profiles are urg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b7bdd6041dc9fe23b1c25340f68bfa2
https://doi.org/10.1101/2020.02.27.20027557
https://doi.org/10.1101/2020.02.27.20027557
Publikováno v:
Autophagy
DDX58/RIG-I, is a critical pattern recognition receptor for viral RNA, which plays an essential role in antiviral immunity. Its posttranslational modifications and stability are tightly regulated to mediate the moderate production of type I IFN to ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73de6c4ca10c7b6032755fe38bb6c83e