Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Huidan Tan"'
Autor:
Xiaosa Chang, Dejuan Sun, Danfeng Shi, Guan Wang, Yanmei Chen, Kai Zhang, Huidan Tan, Jie Liu, Bo Liu, Liang Ouyang
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 1, Pp 156-180 (2021)
This study was aimed to design the first dual-target small-molecule inhibitor co-targeting poly (ADP-ribose) polymerase-1 (PARP1) and bromodomain containing protein 4 (BRD4), which had important cross relation in the global network of breast cancer,
Externí odkaz:
https://doaj.org/article/a815c10815474d82993eefefa638b7fe
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Fam20C, a typical member of Fam20 family, has been well-known as a Golgi casein kinase, which is closely associated with Raine Syndrome (RS). It can phosphorylate many secreted proteins and multiple substrates, and thereby plays a crucial role in bio
Externí odkaz:
https://doaj.org/article/9d9f0cf3539142bcb52c3d5157b5306d
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Natural products are well-characterized to have pharmacological or biological activities that can be of therapeutic benefits for cancer therapy, which also provide an important source of inspiration for discovery of potential novel small-molecule dru
Externí odkaz:
https://doaj.org/article/22d4ab34e2f342019e1e8c63e9adb6be
Publikováno v:
Lecture Notes in Business Information Processing ISBN: 9783031322983
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1772ece62ac125a4b2076512d5a03ef1
https://doi.org/10.1007/978-3-031-32299-0_20
https://doi.org/10.1007/978-3-031-32299-0_20
Publikováno v:
Biomass Conversion and Biorefinery.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::547b6193927841349b1af4a1d2887b94
https://doi.org/10.1007/s13399-022-03009-8
https://doi.org/10.1007/s13399-022-03009-8
Autor:
Bo Liu, Yanmei Chen, Yi Chen, Shouyue Zhang, Huidan Tan, Lingjuan Zhu, Jin Zhang, Yang An, Hongmei Yang
Publikováno v:
Theranostics
Gastric cancer (GC) is currently the fourth most common malignancy and the third leading cause of cancer-related deaths worldwide. Long non-coding RNAs (lncRNAs), transcriptional products with more than 200 nucleotides, are not as well-characterized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee5cb033fc9358383fc30e88bf800763
https://doi.org/10.7150/thno.47548
https://doi.org/10.7150/thno.47548
Autor:
Li He, Minru Liao, Yanmei Chen, Wenke Jin, Bo Liu, Rongyan Zhao, Wei Su, Huidan Tan, Shiou Zhu, Yiwen Zhang
Publikováno v:
Cell Proliferation
Objectives Autophagy, a highly conserved lysosomal degradation process in eukaryotic cells, has been widely reported closely related to the progression of many types of human cancers, including LGG; however, the intricate relationship between autopha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3eb72c4f951d6c50ab1d326f5b282b82
http://europepmc.org/articles/PMC8666277
http://europepmc.org/articles/PMC8666277
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Frontiers in Pharmacology
Frontiers in Pharmacology
Natural products are well-characterized to have pharmacological or biological activities that can be of therapeutic benefits for cancer therapy, which also provide an important source of inspiration for discovery of potential novel small-molecule dru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e2284f53656b987aea604984487098c
https://doi.org/10.3389/fphar.2021.748149
https://doi.org/10.3389/fphar.2021.748149
Publikováno v:
Drug discovery today. 27(1)
Bromodomain-containing protein 4 (BRD4) is emerging as a therapeutic target that acts synergistically with other targets of small-molecule drugs in cancer. Therefore, the discovery of potential new dual-target inhibitors of BRD4 may be a promising st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5347ad4ab47e6ffe727d170afc439eef
https://pubmed.ncbi.nlm.nih.gov/34438075
https://pubmed.ncbi.nlm.nih.gov/34438075
Publikováno v:
Pharmacological research. 173
Epigenetics mainly refers to covalent modifications to DNA or histones without affecting genomes, which ultimately lead to phenotypic changes in cells or organisms. Given the abundance of regulatory targets in epigenetic pathways and their pivotal ro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9433830f727e459ce8866e1c013e345
https://pubmed.ncbi.nlm.nih.gov/34102228
https://pubmed.ncbi.nlm.nih.gov/34102228