Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Huida Wan"'
Publikováno v:
iScience, Vol 9, Iss , Pp 382-398 (2018)
Summary: Endoplasmic reticulum (ER)-to-Golgi anterograde transport is driven by COPII vesicles mainly composed of a Sec23/Sec24 inner shell and a Sec13/Sec31 outer cage. How COPII vesicles are tethered to the Golgi is not completely understood. We de
Externí odkaz:
https://doaj.org/article/a5c5989c984a404fb7a97645a6e55787
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Enalaprilat is the active metabolite of enalapril, a widely used antihypertension drug. The human organic anion transporter 3 (OAT3), which is highly expressed in the kidney, plays a critical role in the renal clearance of many drugs. While urinary e
Externí odkaz:
https://doaj.org/article/a226b4e6e7854c6987985a32732f426e
Autor:
Yunpeng Zhang, Xiusheng Chen, Xiangyu Guo, Zhuchi Tu, Zhifu Wang, Huida Wan, Xin Xiong, Rui Han, Sen Yan, Xiao-Jiang Li, Yanting Liu, Shihua Li, Lujian Liao, Jifeng Guo, Xianxian Zhao, Peng Yin, Xiao-Xin Yan, Huiming Yang, Xingxing Chen, Qi Wang, Weili Yang
Publikováno v:
Protein & Cell
In vitro studies have established the prevalent theory that the mitochondrial kinase PINK1 protects neurodegeneration by removing damaged mitochondria in Parkinson’s disease (PD). However, difficulty in detecting endogenous PINK1 protein in rodent
Publikováno v:
iScience, Vol 9, Iss, Pp 382-398 (2018)
iScience
iScience
Summary Endoplasmic reticulum (ER)-to-Golgi anterograde transport is driven by COPII vesicles mainly composed of a Sec23/Sec24 inner shell and a Sec13/Sec31 outer cage. How COPII vesicles are tethered to the Golgi is not completely understood. We dem
Publikováno v:
Cell Death & Differentiation. 25:904-917
PINK1 mutations that disrupt its kinase activity cause autosomal recessive early onset Parkinson's disease (PD). Although research in recent years has elucidated a PINK1-Parkin pathway of mitophagy activation that requires PINK1 kinase activity, mito
Publikováno v:
Journal of Organometallic Chemistry. 822:100-103
C H bond activation is an important issue. The Pd-catalyzed and non-coordinating anion improved C H bond activation was realized through the oxidative coupling reaction of anilides with olefins under non-acidic conditions. Additionally, the catalytic
Publikováno v:
Tetrahedron Letters. 57:5211-5214
A convenient and simple method for copper-catalyzed synthesis of 2-(arylthio)phenols through C–H functionalization of arylthiols and aryl iodides was developed under ligand-free conditions without nitrogen protection. In addition, arylthioquinone d
Publikováno v:
Tetrahedron Letters. 57:4588-4591
An efficient synthesis of secondary amines has been described through alanine triazole iridium-catalyzed C–N bond formation of an aromatic amine and an alkyl amine using the borrowing hydrogen strategy. In addition, it was observed that alanine tri
Publikováno v:
Synlett. 27:2616-2620
An efficient, ligand-free, transition-metal-free, direct arylation and esterification reaction of unprotected indolylcarboxylic acid derivatives with diaryliodonium salts was developed, thus providing a new entry to 2-(1H-indol-2-yl)-5-(phenylthio)-1
Publikováno v:
RSC Advances. 6:62298-62301
The efficient copper and triphenylphosphine-promoted sulfenylation of quinones with arylsulfonyl chlorides has been developed under mild conditions with moderate to good yields. Significantly, this provides an alternative method to synthesise arylthi