Zobrazeno 1 - 10
of 167
pro vyhledávání: '"Huichen Guo"'
Autor:
Haozhou Li, Pan Liu, Hu Dong, Aldo Dekker, Michiel M. Harmsen, Huichen Guo, Xiangxi Wang, Shiqi Sun
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Unlike most other picornaviruses, foot-and-mouth disease (FMD) intact virions (146S) dissociate easily into small pentameric subunits (12S). This causes a dramatically decreased immunogenicity by a mechanism that remains elusive. Here, we pr
Externí odkaz:
https://doaj.org/article/e550e8eba349473b80436111dddd8b18
Publikováno v:
Veterinary Research, Vol 55, Iss 1, Pp 1-22 (2024)
Abstract Picornaviridae are non-enveloped ssRNA viruses that cause diseases such as poliomyelitis, hand-foot-and-mouth disease (HFMD), hepatitis A, encephalitis, myocarditis, and foot-and-mouth disease (FMD). Virus-like particles (VLPs) vaccines main
Externí odkaz:
https://doaj.org/article/0b6312da0eaa48d6a844badf8aa780b3
Autor:
Linjie Li, Shuanghui Yin, Jingjing Zhou, Liping Zhang, Zhidong Teng, Lu Qiao, Yunhang Wang, Jiaxi Yu, Haoyue Zang, Yaozhong Ding, Xinsheng Liu, Shiqi Sun, Huichen Guo
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
Porcine epidemic diarrhea virus (PEDV) is considered the cause for porcine epidemic diarrhea (PED) outbreaks and hefty losses in pig farming. However, no effective commercial vaccines against PEDV mutant strains are available nowadays. Here, we const
Externí odkaz:
https://doaj.org/article/542fed7b7f174f739d55c9d068521b06
Autor:
Jin'en Wu, Chao Sun, Junyong Guan, Sahibzada Waheed Abdullah, Xuefei Wang, Mei Ren, Lu Qiao, Shiqi Sun, Huichen Guo
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 3 (2024)
ABSTRACTThe internal ribosome entry site (IRES) element constitutes a cis-acting RNA regulatory sequence that recruits the ribosomal initiation complex in a cap-independent manner, assisted by various RNA-binding proteins and IRES trans-acting factor
Externí odkaz:
https://doaj.org/article/72d7749ecc90495487ac2cbc4542a815
Autor:
Hetao Song, Sahibzada Waheed Abdullah, Chenchen Pei, Xiaoni Shi, Xiangyang Chen, Yuqing Ma, Shuanghui Yin, Shiqi Sun, Yong Huang, Huichen Guo
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 1, p 596 (2024)
Classical swine fever virus (CSFV) is a highly contagious pathogen causing significant economic losses in the swine industry. Conventional inactivated or attenuated live vaccines for classical swine fever (CSF) are effective but face biosafety concer
Externí odkaz:
https://doaj.org/article/2d9e1c53fc73401bbd4290d95f7620b3
Autor:
Yanzhen Lu, Ruiming Yu, Lixin Tong, Liping Zhang, Zhongwang Zhang, Li Pan, Yonglu Wang, Huichen Guo, Yonghao Hu, Xinsheng Liu
Publikováno v:
Viruses, Vol 16, Iss 1, p 74 (2023)
Porcine epidemic diarrhea virus (PEDV) and porcine deltacoronavirus (PDCoV) are the two most prevalent swine enteric coronaviruses worldwide. They commonly cause natural coinfections, which worsen as the disease progresses and cause increased mortali
Externí odkaz:
https://doaj.org/article/0a35f9ec4b054b67a5751b0f940a6190
Autor:
Chenchen Pei, Hu Dong, Zhidong Teng, Sumin Wei, Yun Zhang, Shuanghui Yin, Jianli Tang, Shiqi Sun, Huichen Guo
Publikováno v:
Vaccines, Vol 11, Iss 11, p 1675 (2023)
Nanovaccines based on self−assembling nanoparticles (NPs) can show conformational epitopes of antigens and they have high immunogenicity. In addition, flagellin, as a biological immune enhancer, can be fused with an antigen to considerably enhance
Externí odkaz:
https://doaj.org/article/7017f09112224fc4906723a2a2624b7d
Publikováno v:
mBio, Vol 14, Iss 2 (2023)
ABSTRACT Viruses lack the properties to replicate independently due to the limited resources encoded in their genome; therefore, they hijack the host cell machinery to replicate and survive. Picornaviruses get the prerequisite for effective protein s
Externí odkaz:
https://doaj.org/article/c37363722e8e4c71a02936b313a1e771
Autor:
Shuo Li, Ruichong Zhao, Hetao Song, Songjia Pan, Yun Zhang, Hu Dong, Manyuan Bai, Shiqi Sun, Huichen Guo, Shuanghui Yin
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
IntroductionFoot-and-mouth disease virus (FMDV) infects the host by invading mucosal epithelial cells of the respiratory or digestive tract. Therefore, establishing a specific antiviral mucosal immune barrier can effectively block viral invasion.Meth
Externí odkaz:
https://doaj.org/article/dd6773c524094d8089161380f6c5c157
Autor:
Chun Miao, Sicheng Yang, Junjun Shao, Guangqing Zhou, Yunyun Ma, Shenghui Wen, Zhuo Hou, Decai Peng, HuiChen Guo, Wei Liu, Huiyun Chang
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
African swine fever virus (ASFV) causes a highly lethal hemorrhagic viral disease (ASF) of pigs that results in serious losses in China and elsewhere. The development of a vaccine and diagnosis technology for ASFV is essential to prevent and control
Externí odkaz:
https://doaj.org/article/bbbc88ad0ed44b30ab9ae47361b0026c