Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Huichao Qiao"'
Autor:
Stefania Re Depaolini, Tõnu Vooder, Paul-Albert Koenig, Jana Zecha, Mathias Wilhelm, Florian Bassermann, Harald Polzer, Tobias Schmidt, Hannes Hahne, Jan Huenges, Judith Schlegl, Axel Walch, Irmela Jeremias, Stephanie Heinzlmeir, Binje Vick, Bernhard Kuster, Bjoern-Oliver Gohlke, Dominic Helm, Karsten Spiekermann, Karl Kramer, Daniel P Zolg, Neeme Tõnisson, Juergen Ruland, Hans-Christian Ehrlich, Annette Feuchtinger, Wilhelm Becker, Benjamin Ruprecht, Katharina Götze, Svenja Petzoldt, Stephan Aiche, Lars Rueckert, Susan Klaeger, Sabine Schneider, Melanie Schoof, Anne-Kathrin Garz, Maria Reinecke, G. Canevari, Eduard R. Felder, Guillaume Médard, Chen Meng, Philipp A. Greif, Gian Kayser, Elena Casale, Zhixiang Wu, Robert Preissner, Heiner Koch, Huichao Qiao, Katrin Reiter
Publikováno v:
Science
Science 358:eaan4368 (2017)
Science 358:eaan4368 (2017)
An atlas for drug interactions Kinase inhibitors are an important class of drugs that block certain enzymes involved in diseases such as cancer and inflammatory disorders. There are hundreds of kinases within the human body, so knowing the kinase “
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70c60ba549cf2fdbc5a8c4a800cc31b3
Autor:
Benjamin Ruprecht, Dominic Helm, Krishna Saxena, Guillaume Médard, Harald Schwalbe, Huichao Qiao, Denis Kudlinzki, Susan Klaeger, Mathias Wilhelm, Verena Linhard, Stephanie Heinzlmeir, Bernhard Kuster, Santosh Lakshmi Gande, Sridhar Sreeramulu
Publikováno v:
ACS chemical biology. 11(12)
The receptor tyrosine kinase EPHA2 (Ephrin type-A receptor 2) plays important roles in oncogenesis, metastasis, and treatment resistance, yet therapeutic targeting, drug discovery, or investigation of EPHA2 biology is hampered by the lack of appropri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a836f3691aac919670d47eba86d16cc
https://pubmed.ncbi.nlm.nih.gov/27768280
https://pubmed.ncbi.nlm.nih.gov/27768280
Autor:
Marcus Bantscheff, Jessica Perrin, Hiroshi Handa, Robert Preissner, Mikhail M. Savitski, Stephanie Heinzlmeir, Dominic Helm, Bernhard Kuster, Bjoern Oliver Gohlke, Guillaume Médard, Huichao Qiao, Vipul Gupta, Susan Klaeger, Giovanna Bergamini
Publikováno v:
ACS chemical biology. 11(5)
Many protein kinases are valid drug targets in oncology because they are key components of signal transduction pathways. The number of clinical kinase inhibitors is on the rise, but these molecules often exhibit polypharmacology, potentially elicitin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fea7fe2ea56eb9e7c2607811861d84bb
https://pubmed.ncbi.nlm.nih.gov/26863403
https://pubmed.ncbi.nlm.nih.gov/26863403
Autor:
Susan Klaeger, Benjamin Ruprecht, Zhixiang Wu, Fiona Pachl, Carsten Hopf, Karl Kramer, Xin Ku, Stephanie Heinzlmeir, Dominic Helm, Guillaume Médard, Antje Dittmann, Bernhard Kuster, Mathias Wilhelm, Huichao Qiao, Thomas Kuehne
Publikováno v:
Journal of proteome research. 14(3)
Solid supported probes have proven to be an efficient tool for chemical proteomics. The kinobeads technology features kinase inhibitors covalently attached to Sepharose for affinity enrichment of kinomes from cell or tissue lysates. This technology,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fb0e4eba5ec6f53fbf4dbf32171faab
https://pubmed.ncbi.nlm.nih.gov/25660469
https://pubmed.ncbi.nlm.nih.gov/25660469
Autor:
Médard, Guillaume, Pachl, Fiona, Ruprecht, Benjamin, Klaeger, Susan, Heinzlmeir, Stephanie, Helm, Dominic, Huichao Qiao, Xin Ku, Wilhelm, Mathias, Kuehne, Thomas, Zhixiang Wu, Dittmann, Antje, Hopf, Carsten, Kramer, Karl, Kuster, Bernhard
Publikováno v:
Journal of Proteome Research; Mar2015, Vol. 14 Issue 3, p1574-1586, 13p