Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Huichang B"'
Autor:
Shuang Hu, Chenghua Wu, Dan Li, Xiaowen Jiang, Peng Wang, Guofang Bi, Hui Ouyang, Fengting Liang, Wenhong Zhou, Xiao Yang, Jian-Hong Fang, Huichang Bi
Publikováno v:
Pharmacological Research, Vol 210, Iss , Pp 107504- (2024)
Liver regeneration is a complex process that involves the recruitment of bone marrow (BM)-derived hematopoietic stem and progenitor cells (HSPCs). Pregnane X receptor (PXR), also known as NR1I2, is an important regulator for liver enlargement and reg
Externí odkaz:
https://doaj.org/article/4e285a38700d4f66a6d513844de31fcf
Autor:
Qian Liu, Simin Zhang, Xiangyang Qu, Yunhui Xing, Zhenwei Xiao, Shicheng Fan, Janshon Zhu, Min Huang, Huichang Bi
Publikováno v:
Journal of Pharmaceutical Analysis, Vol 14, Iss 11, Pp 101017- (2024)
Externí odkaz:
https://doaj.org/article/54379f055e9b4239b2443d5ede5856f9
Autor:
Shicheng Fan, Yue Gao, Pengfei Zhao, Guomin Xie, Yanying Zhou, Xiao Yang, Xuan Li, Shuaishuai Zhang, Frank J. Gonzalez, Aijuan Qu, Min Huang, Huichang Bi
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 7, Pp 2992-3008 (2024)
Fenofibrate, a peroxisome proliferator-activated receptor α (PPARα) agonist, is widely prescribed for hyperlipidemia management. Recent studies also showed that it has therapeutic potential in various liver diseases. However, its effects on hepatom
Externí odkaz:
https://doaj.org/article/ffaca6e6008341c9ac5e6816bba27d5b
Autor:
Xiaopeng Peng, Zhihao Hu, Limei Zeng, Meizhu Zhang, Congcong Xu, Benyan Lu, Chengpeng Tao, Weiming Chen, Wen Hou, Kui Cheng, Huichang Bi, Wanyi Pan, Jianjun Chen
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 2, Pp 533-578 (2024)
Epigenetic pathways play a critical role in the initiation, progression, and metastasis of cancer. Over the past few decades, significant progress has been made in the development of targeted epigenetic modulators (e.g., inhibitors). However, epigene
Externí odkaz:
https://doaj.org/article/e9f9f251319d4fdf92ac3cb5930c5c4c
Autor:
Tingting Zhao, Guoping Zhong, Ying Wang, Renjie Cao, Shaofei Song, Yuan Li, Guohui Wan, Haiyan Sun, Min Huang, Huichang Bi, Yiming Jiang
Publikováno v:
Advanced Science, Vol 11, Iss 19, Pp n/a-n/a (2024)
Abstract Endotoxemia‐related acute liver injury has a poor prognosis and high mortality, and macrophage polarization plays a central role in the pathological process. Pregnane X receptor (PXR) serves as a nuclear receptor and xenosensor, safeguardi
Externí odkaz:
https://doaj.org/article/c630efba2a8943f096eb0e901328c25d
Autor:
Yixin Chen, Mei-Juan Tu, Fangwei Han, Zhenzhen Liu, Neelu Batra, Primo N. Lara, Hong-Wu Chen, Huichang Bi, Ai-Ming Yu
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 10, Pp 4273-4290 (2023)
During the development of therapeutic microRNAs (miRNAs or miRs), it is essential to define their pharmacological actions. Rather, miRNA research and therapy mainly use miRNA mimics synthesized in vitro. After experimental screening of unique recombi
Externí odkaz:
https://doaj.org/article/f4d6176f67c746b9918b7333fa7e1e5b
Autor:
Ling Ye, Shicheng Fan, Pengfei Zhao, Chenghua Wu, Menghua Liu, Shuang Hu, Peng Wang, Hongyu Wang, Huichang Bi
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 9, Pp 3598-3637 (2023)
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has spread worldwide. Effective treatments against COVID-19 remain urgently in need although vaccination significantly reduces the incidence,
Externí odkaz:
https://doaj.org/article/c73ddfb3bbc340aba6e22302797c3a68
Autor:
Xuan Li, Shicheng Fan, Chenghui Cai, Yue Gao, Xinhui Wang, Yifei Zhang, Hangfei Liang, Huilin Li, Jie Yang, Min Huang, Huichang Bi
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 4, Pp 1588-1599 (2023)
Liver is the central hub regulating energy metabolism during feeding-fasting transition. Evidence suggests that fasting and refeeding induce dynamic changes in liver size, but the underlying mechanisms remain unclear. Yes-associated protein (YAP) is
Externí odkaz:
https://doaj.org/article/61621c7d52674fc4822c30c5491ecaf8
Autor:
Rui Liu, Panpan Liu, Huichang Bi, Jianhua Ling, Huiqin Zhang, Mingquan Zhang, Yumin Hu, Paul J Chiao, Peng Huang, Jinyun Liu
Publikováno v:
Cancer Communications, Vol 43, Iss 2, Pp 285-289 (2023)
Externí odkaz:
https://doaj.org/article/8b58280c81754fb3b65995d14a7e3529
Autor:
Yulian Chen, Huanguo Jiang, Zhikun Zhan, Jindi Lu, Tanwei Gu, Ping Yu, Weimin Liang, Xi Zhang, Shuwen Liu, Huichang Bi, Shilong Zhong, Lan Tang
Publikováno v:
Cell Death and Disease, Vol 14, Iss 2, Pp 1-17 (2023)
Abstract Converting lipid disturbances in response to energy oversupply into healthy lipid homeostasis is a promising therapy to alleviate hepatosteatosis. Our clinical studies found that a further elevation of triglyceride (TG) in obese patients wit
Externí odkaz:
https://doaj.org/article/7125b95eed4c4850a7722c5c696a9bdf