Zobrazeno 1 - 10
of 235
pro vyhledávání: '"Huib N. Caron"'
Autor:
Thomas F. Eleveld, Lindy Vernooij, Linda Schild, Bianca Koopmans, Lindy K. Alles, Marli E. Ebus, Rana Dandis, Harm van Tinteren, Huib N. Caron, Jan Koster, Max M. van Noesel, Godelieve A. M. Tytgat, Selma Eising, Rogier Versteeg, M. Emmy M. Dolman, Jan J. Molenaar
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionMutations affecting the RAS-MAPK pathway occur frequently in relapsed neuroblastoma tumors and are associated with response to MEK inhibition in vitro. However, these inhibitors alone do not lead to tumor regression in vivo, indicating th
Externí odkaz:
https://doaj.org/article/f113f91a5d74419a8ac27a8cd36776b9
Autor:
Evelien G. E. Hurkmans, Marije J. Klumpers, Cinzia Dello Russo, Ward De Witte, Henk-Jan Guchelaar, Hans Gelderblom, Anne-Marie Cleton-Jansen, Sita H. Vermeulen, Suzanne Kaal, Winette T. A. van der Graaf, Uta Flucke, Corrie E. M. Gidding, Hendrik W. B. Schreuder, Eveline S. J. M. de Bont, Huib N. Caron, Giovanna Gattuso, Elisabetta Schiavello, Monica Terenziani, Maura Massimino, Geoff McCowage, Sumanth Nagabushan, Anuja Limaye, Victoria Rose, Daniel Catchpoole, Andrea L. Jorgensen, Christopher Barton, Lucy Delaney, Daniel B. Hawcutt, Munir Pirmohamed, Barry Pizer, Marieke J. H. Coenen, D. Maroeska W. M. te Loo
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2023)
Hearing loss (ototoxicity) is a major adverse effect of cisplatin and carboplatin chemotherapy. The aim of this study is to identify novel genetic variants that play a role in platinum-induced ototoxicity. Therefore, a genome-wide association study w
Externí odkaz:
https://doaj.org/article/a8f79afc4fc54f8c9b487d722feb88e0
Autor:
Ingrid M. Ariës, Rosanna E. van den Dungen, Marco J. Koudijs, Edwin Cuppen, Emile Voest, Jan J. Molenaar, Huib N. Caron, Rob Pieters, Monique L. den Boer
Publikováno v:
Haematologica, Vol 100, Iss 4 (2015)
Externí odkaz:
https://doaj.org/article/55a2aff071ed47dc9d53676d852bcff3
Autor:
Stefanie A. Hartsink-Segers, Carla Exalto, Matthew Allen, Daniel Williamson, Steven C. Clifford, Martin Horstmann, Huib N. Caron, Rob Pieters, Monique L. Den Boer
Publikováno v:
Haematologica, Vol 98, Iss 10 (2013)
This study investigated Polo-like kinase 1, a mitotic regulator often over-expressed in solid tumors and adult hematopoietic malignancies, as a potential new target in the treatment of pediatric acute lymphoblastic leukemia. Polo-like kinase 1 protei
Externí odkaz:
https://doaj.org/article/d64084b7429e40d3bbaf75329abc7a0e
Autor:
Lou F. Stancato, Julia Schüler, Sara Colombetti, Jan J. Molenaar, Olaf Witt, David J. Shields, Xiao-Nan Li, Huib N. Caron, Malcolm A. Smith, Stefan M. Pfister, Peter J. Houghton, Gilles Vassal
Cancer remains the leading cause of disease-related death in children. For the many children who experience relapses of their malignant solid tumors, usually after very intensive first-line therapy, curative treatment options are scarce. Preclinical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a861d8709719e8ae24af1c0928a06945
https://doi.org/10.1158/1535-7163.c.6543523.v1
https://doi.org/10.1158/1535-7163.c.6543523.v1
Autor:
Lou F. Stancato, Julia Schüler, Sara Colombetti, Jan J. Molenaar, Olaf Witt, David J. Shields, Xiao-Nan Li, Huib N. Caron, Malcolm A. Smith, Stefan M. Pfister, Peter J. Houghton, Gilles Vassal
Supplementary Data from International Consensus on Minimum Preclinical Testing Requirements for the Development of Innovative Therapies For Children and Adolescents with Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b3793fc1fac0eccbd4d8f6522ddbfd9
https://doi.org/10.1158/1535-7163.22522909
https://doi.org/10.1158/1535-7163.22522909
Autor:
Godelieve A.M. Tytgat, Carlijn Voermans, Huib N. Caron, Marta Fiocco, C. Ellen van der Schoot, Max M. van Noesel, Annemarie M.L. Peek, Eric Braakman, Sebastiaan Somers, Henk van den Berg, Jozsef Zsiros, Cor van den Bos, Hannah M. Kansen, Ilse Timmerman, Kathelijne C.J.M. Kraal
CD34+cell harvest yield and quality
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4f16b9a5112653bfca51e840ad1772a
https://doi.org/10.1158/1078-0432.22468298
https://doi.org/10.1158/1078-0432.22468298
Autor:
C. Ellen van der Schoot, Godelieve A.M. Tytgat, Huib N. Caron, Rogier Versteeg, Emmy den Ouden, Fatima Ait Ichou, Janine Stutterheim
Purpose: PCR-based detection of minimal residual disease (MRD) in neuroblastoma (NB) is presently based on NB-specific transcripts. However, the expression of these targets varies between patients and upon treatment, and only PHOX2B is truly specific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d2f0ea3c35baba361322384287b46fb
https://doi.org/10.1158/1078-0432.c.6519767.v1
https://doi.org/10.1158/1078-0432.c.6519767.v1
Autor:
C. Ellen van der Schoot, Godelieve A.M. Tytgat, Huib N. Caron, Rogier Versteeg, Emmy den Ouden, Fatima Ait Ichou, Janine Stutterheim
PDF file - 63K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dc78eacd184373b0136acdca3a6ed4d
https://doi.org/10.1158/1078-0432.22443317
https://doi.org/10.1158/1078-0432.22443317
Autor:
C. Ellen van der Schoot, Godelieve A.M. Tytgat, Huib N. Caron, Rogier Versteeg, Emmy den Ouden, Fatima Ait Ichou, Janine Stutterheim
PDF file - 78K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92a695cfd6dbe9cffd7c81987f3d8a2b
https://doi.org/10.1158/1078-0432.22443314.v1
https://doi.org/10.1158/1078-0432.22443314.v1