Zobrazeno 1 - 10
of 454
pro vyhledávání: '"Huib A M Kerstjens"'
Autor:
Salman Siddiqui, Thys van der Molen, Huib A M Kerstjens, Dave Singh, Chris Brightling, Maarten van den Berge, Alberto Papi, Klaus F Rabe, Leonardo M Fabbri, Monica Kraft, Martijn C Nawijn, Susan Muiser, Tessa M Kole
Publikováno v:
BMJ Open Respiratory Research, Vol 11, Iss 1 (2024)
Background Asthma is a heterogeneous disease with a prevalence and severity that differs between male and female patients.Question What are differences between male and female patients with asthma with regard to asthma control, lung function, inflamm
Externí odkaz:
https://doaj.org/article/9bc70945e83b454984afcfa5cfa39b16
Autor:
Jaime Correia-de-Sousa, David B Price, Sinthia Bosnic-Anticevich, Huib A M Kerstjens, Marjan Kerkhof, Ioanna Tsiligianni, Omar Usmani, P N Richard Dekhuijzen, Janwillem W H Kocks, Lars Dijk, Merijn Driessen, Yoran H Gerritsma, Marika Leving
Publikováno v:
BMJ Open Respiratory Research, Vol 10, Iss 1 (2023)
Background Patients with chronic obstructive pulmonary disease (COPD) may be prescribed multiple inhalers that require different techniques for optimal performance. Mixing devices has been associated with poorer COPD outcomes suggesting that it leads
Externí odkaz:
https://doaj.org/article/0f2f64adb79943299cbf08fd38dbf040
Autor:
Huib A M Kerstjens, Emanuel Citgez, Job van der Palen, Paul van der Valk, Marjolein Brusse-Keizer
Publikováno v:
BMJ Open Respiratory Research, Vol 8, Iss 1 (2021)
Background The blood eosinophil count has been shown to be a promising biomarker for establishing personalised treatment strategies to reduce corticosteroid use, either inhaled or systemic, in chronic obstructive pulmonary disease (COPD). Eosinophil
Externí odkaz:
https://doaj.org/article/e63fef49e35641279c6aa3f185ee0438
Autor:
Huib A M Kerstjens, Motoi Hosoe, Yasuhiro Gon, Kenneth Chapman, Ana-Maria Tanase, Richard van Zyl-Smit, Jorge Maspero, Abhijit Pethe, Xu Shu, Peter D’Andrea
Publikováno v:
BMJ Open Respiratory Research, Vol 8, Iss 1 (2021)
Background Despite currently available standard-of-care inhaled corticosteroid (ICS)/long-acting β2-agonist therapies, a substantial proportion of patients with asthma remain inadequately controlled. This pooled analysis evaluated efficacy and safet
Externí odkaz:
https://doaj.org/article/49086318533947689d17e4cbf918372d
Autor:
Maria Dullaert-de Boer, Onno W Akkerman, Marloes Vermeer, Dorine L J Hess, Huib A M Kerstjens, Richard M Anthony, Tjip S van der Werf, Dick van Soolingen, Adri G M van der Zanden
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0192946 (2018)
[This corrects the article DOI: 10.1371/journal.pone.0190847.].
Externí odkaz:
https://doaj.org/article/6035afcb98a6421180b30e3d9d984c58
Autor:
Sandra H van Oostrom, Peter M Engelfriet, W M Monique Verschuren, Maarten Schipper, Inge M Wouters, Marike Boezen, Henriëtte A Smit, Huib A M Kerstjens, H Susan J Picavet
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0197250 (2018)
The objective of this study was to explore trajectories of lung function decline with age in the general population, and to study the effect of sociodemographic and life style related risk factors, in particular smoking and BMI. For this purpose, we
Externí odkaz:
https://doaj.org/article/58530e514a94452aaa2321e9b2bf9d4e
Autor:
Maria Dullaert-de Boer, Onno W Akkerman, Marloes Vermeer, Dorine L J Hess, Huib A M Kerstjens, Richard M Anthony, Tjip S van der Werf, Dick van Soolingen, Adri G M van der Zanden
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0190847 (2018)
Real time PCR has become a dominant method for the highly sensitive detection of pathogens in clinical material. Real time PCR can generate a fluorescence signal by using fluorescence labelled probes, allowing us to detect and semi quantify the amoun
Externí odkaz:
https://doaj.org/article/fbefe98f39d340cbabd1aaf38d9e8fe6
Autor:
Marcel Hoppentocht, Onno W Akkerman, Paul Hagedoorn, Jan-Willem C Alffenaar, Tjip S van der Werf, Huib A M Kerstjens, Henderik W Frijlink, Anne H de Boer
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0149768 (2016)
RATIONALE:Bronchiectasis is a condition characterised by dilated and thick-walled bronchi. The presence of Pseudomonas aeruginosa in bronchiectasis is associated with a higher hospitalisation frequency and a reduced quality of life, requiring frequen
Externí odkaz:
https://doaj.org/article/6a3ea8b89305427ebc0fc4caefef2dd1
Autor:
Jiska B Snoeck-Stroband, Therese S Lapperre, Peter J Sterk, Pieter S Hiemstra, Henk A Thiadens, H Marike Boezen, Nick H T Ten Hacken, Huib A M Kerstjens, Dirkje S Postma, Wim Timens, Jacob K Sont, GLUCOLD Study Group
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0143793 (2015)
BACKGROUND:The decline in lung function can be reduced by long-term inhaled corticosteroid (ICS) treatment in subsets of patients with chronic obstructive pulmonary disease (COPD). We aimed to identify which clinical, physiological and non-invasive i
Externí odkaz:
https://doaj.org/article/1513374b1de047b49a3310d10aadad64
Autor:
Hoeke A Baarsma, Anita I R Spanjer, Gertruud Haitsma, Lilian H J M Engelbertink, Herman Meurs, Marnix R Jonker, Wim Timens, Dirkje S Postma, Huib A M Kerstjens, Reinoud Gosens
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e25450 (2011)
Chronic obstructive pulmonary disease (COPD) is characterized by abnormal extracellular matrix (ECM) turnover. Recently, activation of the WNT/β-catenin pathway has been associated with abnormal ECM turnover in various chronic diseases. We determine
Externí odkaz:
https://doaj.org/article/e118696a97a74b63b00dba6dfa3b541f