Zobrazeno 1 - 10
of 89
pro vyhledávání: '"HuiYong Zhao"'
Autor:
Huiyong Zhao, Sheng Wei, Dachen Zhou, Yongfan Liu, Zicheng Guo, Chuibao Fang, Xiaoxi Pang, Fei Li, Hui Hou, Xiao Cui
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-10 (2023)
Abstract Inflammation is a core mechanism for oncogenesis. Chemokines act as important mediators of chronic inflammation and the tumour inflammatory response. However, there is limited information on chemokines in hepatocellular carcinoma (HCC), a di
Externí odkaz:
https://doaj.org/article/0f056eb5cf744f8aa7d6fb2ec2b31f79
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 40, Iss , Pp 100900- (2023)
Tumor heterogeneity dominates tumor biological behavior and shapes the tumor microenvironment. However, the mechanisms of tumor genetic features modulate immunity response were not clearly clarified. Tumor associated macrophages (TAMs) exert distinct
Externí odkaz:
https://doaj.org/article/e5f1eb23271e4760833d48b99ae7c298
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract The rotational hydraulic damper has advantages in the design and control of rotational machines. This paper presents a novel hydraulic rotational damper with the characteristic of adjusting the damping coefficient. It is composed of a shell,
Externí odkaz:
https://doaj.org/article/ce314629c82448cfb8407224968995d9
Autor:
Qiang Liu, Anqi Li, Lisha Wang, Wei He, Ling Zhao, Chao Wu, Shasha Lu, Xuanguang Ye, Huiyong Zhao, Xiaohan Shen, Xiuying Xiao, Zebing Liu
Publikováno v:
Molecular Therapy: Oncolytics, Vol 17, Iss , Pp 169-179 (2020)
Despite intensive efforts, a considerable proportion of colorectal cancer (CRC) patients develop local recurrence and distant metastasis. Stomatin-like protein 2 (SLP-2), a member of the highly conserved stomatin superfamily, is upregulated across ca
Externí odkaz:
https://doaj.org/article/01f7a1b3b9464b9995db5aae844c8e4c
Publikováno v:
Engineering Reports, Vol 3, Iss 11, Pp n/a-n/a (2021)
Abstract To extend the functionality of the overrunning clutch. A new overrunning clutch with the characteristic of reverse torque transfer direction at high speed is proposed in this paper. This clutch consists of a traditional one‐way overrunning
Externí odkaz:
https://doaj.org/article/3ea48c881534444e8dc2e5dc25558f6c
Autor:
Shanshan Duan, Loredana Moro, Rui Qu, Daniele Simoneschi, Hyunwoo Cho, Shaowen Jiang, Huiyong Zhao, Qing Chang, Elisa de Stanchina, Arnaldo A. Arbini, Michele Pagano
Publikováno v:
Cell Reports, Vol 37, Iss 3, Pp 109870- (2021)
Summary: FBXO31 is the substrate receptor of one of many CUL1-RING ubiquitin ligase (CRL1) complexes. Here, we show that low FBXO31 mRNA levels are associated with high pre-operative prostate-specific antigen (PSA) levels and Gleason grade in human p
Externí odkaz:
https://doaj.org/article/f42df1e8c44b4669aa236586fa582c8a
Publikováno v:
Jixie chuandong, Vol 43, Pp 171-176 (2019)
A rotating and translating integrated mechanical device is designed. The structure,principle and main components of the device are introduced in detail,and the force acting on the mechanism is analyzed. Taking its application in winch as an examp
Externí odkaz:
https://doaj.org/article/9eb5c0c5d4d74bdea097a34101a774e6
Publikováno v:
IEEE Access, Vol 7, Pp 44307-44316 (2019)
The steering wheel system of steering by wire vehicles usually composed of a steering wheel and a road feel motor. This system provides an artificial road feel in the form of torque generated from road feel motor. The motor consistently consumes ener
Externí odkaz:
https://doaj.org/article/82089d7417954c2f9f23aceb5267f52a
Autor:
Jing Hu, Francisco J. Sánchez-Rivera, Zhenghan Wang, Gabriela N. Johnson, Yu-jui Ho, Karuna Ganesh, Shigeaki Umeda, Siting Gan, Adriana M. Mujal, Rebecca B. Delconte, Jessica P. Hampton, Huiyong Zhao, Sanjay Kottapalli, Elisa de Stanchina, Christine A. Iacobuzio-Donahue, Dana Pe’er, Scott W. Lowe, Joseph C. Sun, Joan Massagué
Publikováno v:
Nature. 616:806-813
Autor:
Rona Yaeger, Riccardo Mezzadra, Jenna Sinopoli, Yu Bian, Michelangelo Marasco, Esther Kaplun, Yijun Gao, HuiYong Zhao, Arnaud Da Cruz Paula, Yingjie Zhu, Almudena Chaves Perez, Kalyani Chadalavada, Edison Tse, Sudhir Chowdhry, Sydney Bowker, Qing Chang, Besnik Qeriqi, Britta Weigelt, Gouri J. Nanjangud, Michael F. Berger, Hirak Der-Torossian, Kenna Anderes, Nicholas D. Socci, Jinru Shia, Gregory J. Riely, Yonina R. Murciano-Goroff, Bob T. Li, James G. Christensen, Jorge S. Reis-Filho, David B. Solit, Elisa de Stanchina, Scott W. Lowe, Neal Rosen, Sandra Misale
Publikováno v:
Cancer Discovery. :OF1-OF15
With the combination of KRASG12C and EGFR inhibitors, KRAS is becoming a druggable target in colorectal cancer. However, secondary resistance limits its efficacy. Using cell lines, patient-derived xenografts, and patient samples, we detected a hetero