Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Hui-fang TANG"'
Autor:
Jie Zhao, Ling Han, Ya-Rong Zhang, Shi-Meng Liu, Deng-Ren Ji, Rui Wang, Yan-Rong Yu, Mo-Zhi Jia, San-Bao Chai, Hui-Fang Tang, Wei Huang, Yong-Fen Qi
Publikováno v:
Pharmaceuticals, Vol 17, Iss 9, p 1204 (2024)
Diabetic cardiomyopathy (DCM), one of the most serious long-term consequences of diabetes, is closely associated with myocardial fatty acid metabolism. Carnitine palmitoyltransferase-1β (CPT-1β) is the rate-limiting enzyme responsible for β-oxidat
Externí odkaz:
https://doaj.org/article/af05f2519bd44e70ac2b0e7b41409612
Autor:
Ya-Jun Li, Jian-Rong Shi, Shu-Chan Li, Lu-Ming Wang, Rana Dhar, Ning Li, Xin-Wei Cao, Zi-Gang Li, Hui-Fang Tang
Publikováno v:
iScience, Vol 26, Iss 5, Pp 106586- (2023)
Summary: Pulmonary fibrosis (PF) is a fatal and irreversible respiratory disease accompanied by excessive fibroblast activation. Previous studies have suggested that cAMP signaling pathway and cGMP-PKG signaling pathway are continuously down-regulate
Externí odkaz:
https://doaj.org/article/0d8c26397b20489eb5b25582adbd17e1
Autor:
Heng-Jing Hu, Xiu-Heng Wang, Yao Liu, Tian-Qing Zhang, Zheng-Rong Chen, Chi Zhang, Zhi-Han Tang, Shun-Lin Qu, Hui-Fang Tang, Zhi-Sheng Jiang
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Atrial fibrosis is the basis for the occurrence and development of atrial fibrillation (AF) and is closely related to the Warburg effect, endoplasmic reticulum stress (ERS) and mitochondrion dysfunctions-induced cardiomyocyte apoptosis. Hydrogen sulf
Externí odkaz:
https://doaj.org/article/500f641513f7455f9fdf58329036b9c7
Publikováno v:
International Journal of Cardiology. 382:60-61
Publikováno v:
International Journal of Cardiology. 382:85-86
Publikováno v:
World Journal of Clinical Cases
BACKGROUND Lower body positive pressure (LBPP) treadmill has potential applications for improving the gait of patients after stroke, but the related mechanism remains unclear. CASE SUMMARY A 62-year-old male patient suffered from ischemic stroke with
Publikováno v:
Current Drug Targets. 21:1056-1067
N6-methyladenine RNA modification (m6A) is an RNA methylation modification catalyzed by methyltransferase at the 6th position nitrogen atom of adenine (A), which is the most common chemical modification of eukaryotic messenger RNA (mRNA). Recently, m
Autor:
Ya-Juan Wang, Shun-De Song, Jun-Chun Chen, Xue-Feng Wang, Ya-Li Jiang, Qiang-Min Xie, Ji-Qiang Chen, Zi-Gang Li, Hui-Fang Tang
Publikováno v:
Pulmonary Medicine, Vol 2014 (2014)
This paper indicated that inactivated Bordetella pertussis (iBp) can enhance the lung airway hyperreactivity of the rats sensitized and challenged with OVA. The mechanisms were involved in the upregulation of cAMP-PDE activity and PDE4A, PDE4D, and P
Externí odkaz:
https://doaj.org/article/914ffee23e4248398133c45c469a36a5
Publikováno v:
Molecular medicine reports. 19(3)
The present study aimed to investigate the potent inhibitory effects and possible biochemical basis of the novel phosphodiesterase 4 (PDE4) inhibitor ciclamilast, which is a derivative of piclamilast (RP 73401), on PDE4 and allergic inflammation. Cic
Autor:
Shun-de, Song, Hui-fang, Tang
Publikováno v:
Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences. 43(3)
cAMP-specific phosphodiesterase type 4 (PDE4) is one of the hot targets for treatment of inflammatory diseases. PDE4 inhibitors can suppress inflammation by increasing the concentration of cAMP in inflammatory cells. The efficacy and safety evaluatio