Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Hui-Yun Hwang"'
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-17 (2021)
Kim, Hwang et al. use in vitro and in vivo models of autophagy disorder/metabolic dysfunction to show that in this context, the natural compound kaempferide is an autophagy enhancer and reveal that one of the underlying mechanisms governing this is m
Externí odkaz:
https://doaj.org/article/ca2eeb930c9945b6b07d31949a91e055
Autor:
Dasol Kim, Kyeong Eun Yang, Dong Won Kim, Hui‐Yun Hwang, Jinyoung Kim, Jong‐Soon Choi, Ho Jeong Kwon
Publikováno v:
Clinical and Translational Medicine, Vol 11, Iss 8, Pp n/a-n/a (2021)
Externí odkaz:
https://doaj.org/article/e58e5f0010f34573b53343e560d32f35
Publikováno v:
Cancers, Vol 14, Iss 8, p 1883 (2022)
Human colon carcinomas, including HCT116 cells, often exhibit high autophagic flux under nutrient deprivation or hypoxic conditions. Mitochondrial ROS (mROS) is known as a ‘molecular switch’ for regulating the autophagic pathway, which is critica
Externí odkaz:
https://doaj.org/article/c1140839a58b41e6ad5c87a52bc783fe
Autor:
Hyejin Lim, Yu-Mi Lim, Kook Hwan Kim, Young Eui Jeon, Kihyoun Park, Jinyoung Kim, Hui-Yun Hwang, Dong Jin Lee, Haushabhau Pagire, Ho Jeong Kwon, Jin Hee Ahn, Myung-Shik Lee
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Autophagy plays an important role in metabolic functions and increased autophagic activity may be beneficial for metabolic disorders. Here the authors screen a chemical library for enhancer of autophagic flux and identify small molecules that improve
Externí odkaz:
https://doaj.org/article/b5027a9d500c443aa7ee8732532b7ad0
Autor:
Hui-Yun Hwang, Yoon Sun Cho, Jin Young Kim, Ki Na Yun, Jong Shin Yoo, Eunhyeong Lee, Injune Kim, Ho Jeong Kwon
Publikováno v:
Cancers, Vol 12, Iss 3, p 543 (2020)
Manipulating autophagy is a promising strategy for treating cancer as several autophagy inhibitors are shown to induce autophagic cell death. One of these, autophagonizer (APZ), induces apoptosis-independent cell death by binding an unknown target vi
Externí odkaz:
https://doaj.org/article/2029cfcb416e4af49b099b39f98c378c
Publikováno v:
Biochemical and Biophysical Research Communications. 568:30-36
Autophagy, the process of lysosomal degradation of biological materials within cells, is often halted abnormally in proteopathies, such as tauopathy and amyloidopathy. Thus, autophagy regulators that rescue dysregulated autophagy have great potential
Publikováno v:
Expert Opinion on Drug Discovery. 15:1045-1063
Small molecules targeting autophagy have been highly implicated as new therapeutic agents to treat diseases of interest. With the increasing demand for autophagy-targeting drugs, this review attempts to provide an efficient strategy to explore major
Mitochondrial ROS Produced in Human Colon Carcinoma HCT116 Cells Reduces Cell Survival via Autophagy
Human colon carcinomas, including HCT116 cells, often exhibit high basal autophagic flux under nutrient deprivation or hypoxic conditions. Mitochondrial ROS (mROS) is known as a “molecular switch”’ for regulating the autophagic pathway, which i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::238c3b5e32a71fd386130085c451aef3
https://doi.org/10.20944/preprints202201.0324.v1
https://doi.org/10.20944/preprints202201.0324.v1
Autor:
Jong-Soon Choi, Dasol Kim, Hui-Yun Hwang, Kyeong Eun Yang, Ho Jeong Kwon, Jin Young Kim, Dong Won Kim
Publikováno v:
Clinical and Translational Medicine, Vol 11, Iss 8, Pp n/a-n/a (2021)
Autor:
Dasol, Kim, Kyeong Eun, Yang, Dong Won, Kim, Hui-Yun, Hwang, Jinyoung, Kim, Jong-Soon, Choi, Ho Jeong, Kwon
Publikováno v:
Clinical and Translational Medicine