Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Hui-Sun Leong"'
Autor:
Joo-Leng Low, Dawn Pingxi Lau, Xiaoqian Zhang, Xue-Lin Kwang, Neha Rohatgi, Jane Vin Chan, Fui-Teen Chong, Stephen Qi Rong Wong, Hui-Sun Leong, Matan Thangavelu Thangavelu, Shivaji Rikka, Anders Martin Jacobsen Skanderup, Daniel Shao Weng Tan, Giridharan Periyasamy, Judice Lie Yong Koh, N Gopalakrishna Iyer, Ramanuj DasGupta
Publikováno v:
EBioMedicine, Vol 66, Iss , Pp 103297- (2021)
Externí odkaz:
https://doaj.org/article/efc7e7970bf04a188a2b4cbd40df635d
Autor:
Joo-Leng Low, Dawn Pingxi Lau, Xiaoqian Zhang, Xue-Lin Kwang, Neha Rohatgi, Jane Vin Chan, Fui-Teen Chong, Stephen Qi Rong Wong, Hui-Sun Leong, Matan Thangavelu Thangavelu, Shivaji Rikka, Anders Martin Jacobsen Skanderup, Daniel Shao Weng Tan, Giridharan Periyasamy, Judice Lie Yong Koh, N Gopalakrishna Iyer, Ramanuj DasGupta
Publikováno v:
EBioMedicine, Vol 64, Iss , Pp 103220- (2021)
Background: Overexpression of epidermal growth factor receptor (EGFR), and downstream pathway activation appears to be a common oncogenic driver in the majority of head and neck squamous cell cancers (HNSCCs); yet targeting EGFR for the treatment of
Externí odkaz:
https://doaj.org/article/a859aa922a95418fb03d43002f362811
Autor:
Athanasios R Paliouras, Marta Buzzetti, Lei Shi, Ian J Donaldson, Peter Magee, Sudhakar Sahoo, Hui‐Sun Leong, Matteo Fassan, Matthew Carter, Gianpiero Di Leva, Matthew G Krebs, Fiona Blackhall, Christine M Lovly, Michela Garofalo
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 7, Pp n/a-n/a (2020)
Abstract A subset of lung adenocarcinomas is driven by the EML4‐ALK translocation. Even though ALK inhibitors in the clinic lead to excellent initial responses, acquired resistance to these inhibitors due to on‐target mutations or parallel pathwa
Externí odkaz:
https://doaj.org/article/6544b05e1c244d05b4afe550ea63b803
Autor:
Shumei Chia, Joo-Leng Low, Xiaoqian Zhang, Xue-Lin Kwang, Fui-Teen Chong, Ankur Sharma, Denis Bertrand, Shen Yon Toh, Hui-Sun Leong, Matan T. Thangavelu, Jacqueline S. G. Hwang, Kok-Hing Lim, Thakshayeni Skanthakumar, Hiang-Khoon Tan, Yan Su, Siang Hui Choo, Hannes Hentze, Iain B. H. Tan, Alexander Lezhava, Patrick Tan, Daniel S. W. Tan, Giridharan Periyasamy, Judice L. Y. Koh, N. Gopalakrishna Iyer, Ramanuj DasGupta
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Treatment response in patient-derived models may serve as a biomarker for response in the clinic. Here, the authors use paired patient-derived mouse xenografts and patient-derived primary culture models from head and neck squamous cell carcinomas, in
Externí odkaz:
https://doaj.org/article/7f061de7c66f4a4eb132f00dff006462
Autor:
Hong Sheng Quah, Elaine Yiqun Cao, Lisda Suteja, Constance H. Li, Hui Sun Leong, Fui Teen Chong, Shilpi Gupta, Camille Arcinas, John F. Ouyang, Vivian Ang, Teja Celhar, Yunqian Zhao, Hui Chen Tay, Jerry Chan, Takeshi Takahashi, Daniel S. W. Tan, Subhra K. Biswas, Owen J. L. Rackham, N. Gopalakrishna Iyer
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
The molecular mechanisms underlying lymph-node metastasis in head and neck squamous-cell carcinoma remain to be investigated. Here, the authors perform single-cell RNA sequencing of cancer cells and CD8 + T cells and suggest potential mechanisms of i
Externí odkaz:
https://doaj.org/article/38255f69fa6848db9cd30e34bbfaa608
Autor:
Michela Garofalo, Matteo Fassan, Hui Sun Leong, Alexander R. Baker, Robert Sellers, Dave Lee, Lei Shi, Peter Magee, Manuela La Montagna, Sudhakar Sahoo, Tiziana Monteverde
Differentially expressed genes in CKAP2L-depleted cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::107bd4d87e96316d5f5b793b0bde05ad
https://doi.org/10.1158/0008-5472.22428415
https://doi.org/10.1158/0008-5472.22428415
Autor:
Michela Garofalo, Matteo Fassan, Hui Sun Leong, Alexander R. Baker, Robert Sellers, Dave Lee, Lei Shi, Peter Magee, Manuela La Montagna, Sudhakar Sahoo, Tiziana Monteverde
Correlation analysis between LuAd gene expression and CIN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b287005a9d1526dc0a70e93b6a682728
https://doi.org/10.1158/0008-5472.22428442.v1
https://doi.org/10.1158/0008-5472.22428442.v1
Autor:
Michela Garofalo, Matteo Fassan, Hui Sun Leong, Alexander R. Baker, Robert Sellers, Dave Lee, Lei Shi, Peter Magee, Manuela La Montagna, Sudhakar Sahoo, Tiziana Monteverde
Supplementary methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d269aabe7e00254b7afe8fc7f2215a8
https://doi.org/10.1158/0008-5472.22428445.v1
https://doi.org/10.1158/0008-5472.22428445.v1
Autor:
Michela Garofalo, Matteo Fassan, Hui Sun Leong, Alexander R. Baker, Robert Sellers, Dave Lee, Lei Shi, Peter Magee, Manuela La Montagna, Sudhakar Sahoo, Tiziana Monteverde
List of all primers used in the study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ed9e49f7b76dc41279e5b483f72b028
https://doi.org/10.1158/0008-5472.22428412
https://doi.org/10.1158/0008-5472.22428412
Autor:
Michela Garofalo, Matteo Fassan, Hui Sun Leong, Alexander R. Baker, Robert Sellers, Dave Lee, Lei Shi, Peter Magee, Manuela La Montagna, Sudhakar Sahoo, Tiziana Monteverde
CKAP2L binding partners were identified by LC-MS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2678c56a088d514a2ade2f8cb2c2781c
https://doi.org/10.1158/0008-5472.22428409.v1
https://doi.org/10.1158/0008-5472.22428409.v1