Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Hui-Quan Yeo"'
Autor:
Haoying Xu, Wei Lin Sandra Sim, Cheah Chen Seh, Feng Wang, Thierry T. Diagana, Wai Ling Chan, Jae-Geun Song, Kah Fei Wan, Bin Zou, Ghislain M. C. Bonamy, David Beer, David T. Barkan, Min Li, Stephanie A. Moquin, Francesca Blasco, Suresh B. Lakshminarayana, Jin Zhang, Oliver Simon, Vito G. Sasseville, Craig W. Day, Qing-Yin Wang, Chandrassegar Saravanan, Katherine Chan, Fumiaki Yokokawa, Bryan K. S. Yeung, Ratna Karuna, Hui-Quan Yeo, Colin Osborne, Christopher Sarko, Pei Yong Shi, Hongping Dong, Mei Ding, Siew Pheng Lim, Yen Liang Chen, Feng Gu, Cyrille Kounde, Gang Wang, Siyan Lu, Wei Liu
Publikováno v:
Science Translational Medicine. 13
Dengue virus (DENV) is a mosquito-borne flavivirus that poses a threat to public health, yet no antiviral drug is available. We performed a high-throughput phenotypic screen using the Novartis compound library and identified candidate chemical inhibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88cb7c9fc29a66acc799682b5292b913
https://doi.org/10.1126/scitranslmed.abb2181
https://doi.org/10.1126/scitranslmed.abb2181
Autor:
Hongping Dong, Bryan K. S. Yeung, Ratna Karuna, Bin Zou, Trixie Wagner, Hui-Quan Yeo, Cyrille Kounde, Oliver Simon, Kah Fei Wan, Qing-Yin Wang, Ghislain M. C. Bonamy, Fumiaki Yokokawa, Ina Dix
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 27:1385-1389
A series of 2-oxopiperazine derivatives were designed from the pyrrolopiperazinone cell-based screening hit 4 as a dengue virus inhibitor. Systematic investigation of the structure-activity relationship (SAR) around the piperazinone ring led to the i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ada04bec55172ef37cc6806daf8ac826
https://doi.org/10.1016/j.bmcl.2017.02.005
https://doi.org/10.1016/j.bmcl.2017.02.005
Publikováno v:
Synlett. 25:201-204
A synthetic method to aminate 1,3-dicarbonyl compounds with PhI=NTs using Bronsted acid catalysis is described herein. The method was shown to be applicable to β-keto esters and phosphonates as well as 1,3-diones, providing the corresponding α,α-a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50db5747bd2ecc267c7b1d2d40950596
https://doi.org/10.1055/s-0033-1340108
https://doi.org/10.1055/s-0033-1340108
Publikováno v:
ChemInform. 45
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3975f93761b6105b037c92d5563ad54f
https://doi.org/10.1002/chin.201428036
https://doi.org/10.1002/chin.201428036
Publikováno v:
Synlett; 2014, Vol. 25 Issue 2, p201-204, 4p