Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Hui-Qi Low"'
Publikováno v:
Humanities & Social Sciences Communications, Vol 11, Iss 1, Pp 1-18 (2024)
Abstract The rising prevalence of harassment in Middle Eastern countries is mirrored in literary works from the region. However, extracting data from these texts to understand the typology and frequency of the cases poses a significant challenge due
Externí odkaz:
https://doaj.org/article/aff312c010e04112839191f0554800ce
Autor:
Yuqing Li, Hui-Qi Low, Jia Nee Foo, Hatef Darabi, Kristjana Einarsdόttir, Keith Humphreys, Amanda Spurdle, ANECS Group, Douglas F Easton, Deborah J Thompson, Alison M Dunning, Paul D P Pharoah, Kamila Czene, Kee Seng Chia, Per Hall, Jianjun Liu
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e42445 (2012)
Given that the transcriptional regulatory activity of estrogen receptor (ER) is modulated by its biochemical cofactors, genetic variation within the ER cofactor genes may alter cellular response to estrogen exposure and consequently modify the risk f
Externí odkaz:
https://doaj.org/article/d4cbe74a61284f7da2aeeb7abd9166e7
Autor:
Qing Yang, Hong Liu, Hui-Qi Low, Haifeng Wang, Yongxiang Yu, Xi'an Fu, Gongqi Yu, Mingfei Chen, Xiaoxiao Yan, Shumin Chen, Wei Huang, Jianjun Liu, Furen Zhang
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e29747 (2012)
BACKGROUND: A genetic component to the etiology of leprosy is well recognized but the mechanism of inheritance and the genes involved are yet to be fully established. METHODOLOGY: A genome-wide single nucleotide polymorphism (SNP) based linkage analy
Externí odkaz:
https://doaj.org/article/f84c7f3c860444fdae5fea4ae82dc1a2
Autor:
Hui-Qi Low, Christopher P L H Chen, Katherine Kasiman, Anbupalam Thalamuthu, Seok-Shin Ng, Jia-Nee Foo, Hui-Meng Chang, Meng-Cheong Wong, E-Shyong Tai, Jianjun Liu
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24757 (2011)
BACKGROUND: The effect of genetic factors, apart from 5,10-methylenetetrahydrofolate reductase (MTHFR) polymorphisms, on elevated plasma homocysteine levels and increasing ischemic stroke risk have not been fully elucidated. We conducted a comprehens
Externí odkaz:
https://doaj.org/article/23034f5251894764bf664fd7aa565055
Autor:
Shumin Chen, Jianjun Liu, L. Xiong, Y. X. Yu, B. Q. Shi, Z. Li, Pengfei Xiao, N. Wang, Herty Liany, Q. Yang, Y. X. Liu, W. B. Wu, C. H. Wang, S. S. Ma, Z. H. Wei, X. D. Wang, Yan Ning, Jin Li, Hui Qi Low, Joshua Le-Wei Li, H. H. Liu, Jyh-Yuan Yang, L. B. Yan, G. Z. Zhou, Zhe Wang, Lianhua Zhang, M. Li, F. F. Bao, Z. Y. Zheng, Tongsheng Chu, G. Q. Yu, Xun Chen, J. Huang, Jin-Xin Bei, R. D. Yang, Sara L. Pulit, Jia Nee Foo, You Zhou, J. Q. Wang, D. C. Liu, M. F. Chen, Fu Ren Zhang, Y. Sun, D. B. Yu, Shaomin Chen, L. M. Wang, Yi Li, J. P. Shen, J. B. You, J. P. Liu, H. Long, Z. S. Liu, Hu Liu, Z. X. Zhang, Astrid Irwanto, Yi Xin Zeng, Zheng-Ming Huang, Xiaoming Jia, X. L. Yu, X. M. Lu, Hui Wang, Guoqing Zhang, Xi'an Fu, H. Q. Tian, P. I. W. de Bakker, G. Y. Niu
Publikováno v:
New England Journal of Medicine. 369:1620-1628
Dapsone is used in the treatment of infections and inflammatory diseases. The dapsone hypersensitivity syndrome, which is associated with a reported mortality of 9.9%, develops in about 0.5 to 3.6% of persons treated with the drug. Currently, no test
Autor:
Hongqing Tian, Hong Liu, H. Liu, Yan Zhou, Chunying Yuan, Shanshan Ma, Fangfang Bao, Nan Lu, Yongxiang Yu, Xi'an Fu, Na Wang, Xuejun Zhang, Shumin Chen, Jianjun Liu, Furen Zhang, Mingfei Chen, Gongqi Yu, Yonghu Sun, Jiabao You, Herty Liany, Jinghui Li, Tongsheng Chu, Guiye Niu, Yi Li, Hui Qi Low, Astrid Irwanto, Jian Liu
Publikováno v:
Human Molecular Genetics
Previous genome-wide association studies (GWASs) identified multiple susceptibility loci that have highlighted the important role of TLR (Toll-like receptor) and CARD (caspase recruitment domain) genes in leprosy. A large three-stage candidate gene-b
Autor:
Hui Qi Low, Jimmy Lee, Hong Liu, Ai Huey Tan, Anne Y.Y. Chan, Tin Aung, Khai Koon Heng, Soo-Hong Chew, Chiea Chuen Khor, Jianjun Liu, Wing Lok Au, Eranga N. Vithana, Shen-Yang Lim, Mythily Subramaniam, Jin-Xin Bei, Richard P. Ebstein, Jia Nee Foo, Chiung Mei Chen, Kumar M. Prakash, Hao Deng, Seang-Mei Saw, Kyuyoung Song, Adeline Seow, Yi-Chun Chen, Tien Yin Wong, Vincent Mok, Hui-Fang Shang, Wee-Yang Meah, Azlina Ahmad-Annuar, Siow Ann Chong, Eng-King Tan, Furen Zhang, Zhong Pei, Rong Peng, Sun Ju Chung, Yih-Ru Wu, E-Shyong Tai, Ching-Yu Cheng, Fook Tim Chew, Louis C.S. Tan, Ishak D. Irwan, Hao Pang
Publikováno v:
Human molecular genetics. 26(1)
Genome-wide association studies (GWAS) on Parkinson’s disease (PD) have mostly been done in Europeans and Japanese. No study has been done in Han Chinese, which make up nearly a fifth of the world population. We conducted the first Han Chinese GWAS
Autor:
Dermot P.B. McGovern, Jiwon Baek, Jianjun Liu, Kyuyoung Song, Hyoung Doo Shin, Kyung-Jo Kim, Suk-Kyun Yang, Hyunjung Oh, Seonjoo Ahn, Buhm Han, Ho-Su Lee, Inchul Lee, Eunji Kim, Sang Hyoung Park, Kyung Mo Kim, Hui Qi Low, Cue Hyunkyu Lee, Young Jin Kim, Byong Duk Ye, Seulgi Jung, Myunghee Hong
Publikováno v:
Gastroenterology. 151(6)
Recent genome-wide association studies have identified more than 200 regions that affect susceptibility to inflammatory bowel disease (IBD). However, identified common variants account for only a fraction of IBD heritability and largely have been ide
Autor:
Mingfei Chen, Xuejun Zhang, Shanshan Ma, Yonghu Sun, Dianchang Liu, Furen Zhang, Xi'an Fu, Guiye Niu, Na Wang, Jinghui Li, Astrid Irwanto, Yan Zhou, Chuan Wang, Jiabao You, Hongqing Tian, Jianjun Liu, Qing Yang, Shumin Chen, Benqing Shi, Yi Li, Gongqi Yu, Lin Zhang, Chunying Yuan, Hui Qi Low, Tongsheng Chu, Nan Lu, Fangfang Bao, H. Liu, Hong Liu, Jian Liu, Xiulu Yu, Yongxiang Yu
Publikováno v:
The American Journal of Human Genetics. 91:935-941
Of eight leprosy susceptibility loci identified by genome-wide association studies, five have been implicated in Crohn disease, suggesting a common genetic fingerprint between leprosy and inflammatory bowel disease (IBD). Here, we conducted a multipl
Autor:
Kar Seng Sim, Rongshan Li, Li Zhu, Xianyong Yin, Hong Zhang, Jian Xin Wan, Jin Quan Wang, Jianjun Liu, Jian Chen, Wei Wang, Xue Qing Tang, Zhi Jian Li, Li Fan, Ming Li, Xin Wei, Zhang Suo Liu, Xuejun Zhang, Xueqing Yu, Yi Li, Hui Qi Low, Liangdan Sun, Xiao Jun Huang, Liu Zhihong, Jia Nee Foo, Tan Qi Lou
Publikováno v:
Nature Genetics. 44:178-182
We performed a two-stage genome-wide association study of IgA nephropathy (IgAN) in Han Chinese, with 1,434 affected individuals (cases) and 4,270 controls in the discovery phase and follow-up of the top 61 SNPs in an additional 2,703 cases and 3,464