Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Hui-Pan Wu"'
Publikováno v:
Journal of Medicinal Chemistry. 64:1362-1391
Histone deacetylases (HDACs) are essential for maintaining homeostasis by catalyzing histone deacetylation. Aberrant expression of HDACs is associated with various human diseases. Although HDAC inhibitors are used as effective chemotherapeutic agents
Publikováno v:
Bioorganic Chemistry. 109:104754
Tumor immunotherapy is currently subject of intense scientific and clinical developments. In previous decade, therapists used natural immune system from the human body to treat several diseases. Although tumor immune disease is a big challenge, combi
Autor:
Yuan-Yuan Tao, Bing Zhao, Bo-Wang, Zhang-Xu He, Qin Ma, Hong-Min Liu, Haojie Wang, Xin-Hui Zhang, Hui-Pan Wu, Li-Ying Ma, Yi-Han Li
Publikováno v:
European Journal of Medicinal Chemistry. 199:112349
In this paper, a series of thiosemicarbazone derivatives containing different aromatic heterocyclic groups were synthesized and the tridentate donor system of the lead compound was optimized. Most of the target compounds showed improved antiprolifera