Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Hui-Ju Wen"'
Publikováno v:
Epidemiology and Health, Vol 44 (2022)
OBJECTIVES This study investigated the association between allergen sensitization and current asthma in children in the United States using data from the 2005-2006 National Health and Nutrition Examination Survey (NHANES). METHODS Children who partic
Externí odkaz:
https://doaj.org/article/2769a80a146d4972b6a60cd63b7f5e9d
Autor:
Samuel A Kerk, Lin Lin, Amy L Myers, Damien J Sutton, Anthony Andren, Peter Sajjakulnukit, Li Zhang, Yaqing Zhang, Jennifer A Jiménez, Barbara S Nelson, Brandon Chen, Anthony Robinson, Galloway Thurston, Samantha B Kemp, Nina G Steele, Megan T Hoffman, Hui-Ju Wen, Daniel Long, Sarah E Ackenhusen, Johanna Ramos, Xiaohua Gao, Zeribe C Nwosu, Stefanie Galban, Christopher J Halbrook, David B Lombard, David R Piwnica-Worms, Haoqiang Ying, Marina Pasca di Magliano, Howard C Crawford, Yatrik M Shah, Costas A Lyssiotis
Publikováno v:
eLife, Vol 11 (2022)
Mitochondrial glutamate-oxaloacetate transaminase 2 (GOT2) is part of the malate-aspartate shuttle, a mechanism by which cells transfer reducing equivalents from the cytosol to the mitochondria. GOT2 is a key component of mutant KRAS (KRAS*)-mediated
Externí odkaz:
https://doaj.org/article/3f6b7faa3ebf44d494617d12f6cd6c1c
Autor:
Paloma E. Garcia, Maeva Adoumie, Esther C. Kim, Yaqing Zhang, Michael K. Scales, Yara S. El-Tawil, Amara Z. Shaikh, Hui-Ju Wen, Filip Bednar, Ben L. Allen, Deneen M. Wellik, Howard C. Crawford, Marina Pasca di Magliano
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 10, Iss 3, Pp 581-599 (2020)
Background & Aims: Although the healthy pancreas consists mostly of epithelial cells, pancreatic cancer and the precursor lesions known as pancreatic intraepithelial neoplasia, are characterized by an extensive accumulation of fibroinflammatory strom
Externí odkaz:
https://doaj.org/article/cb4adafea5b946caafb98261bca46224
Autor:
Hui-Ju Wen, Shan Gao, Yin Wang, Michael Ray, Mark A. Magnuson, Christopher V.E. Wright, Marina Pasca Di Magliano, Timothy L. Frankel, Howard C. Crawford
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 8, Iss 2, Pp 173-192 (2019)
Background & Aims: Pancreatitis is a major cause of morbidity and mortality and is a risk factor for pancreatic tumorigenesis. Upon tissue damage, an inflammatory response, made up largely of macrophages, provides multiple growth factors that promote
Externí odkaz:
https://doaj.org/article/0bcf60c741024912b043544219441d02
Publikováno v:
Environment International, Vol 145, Iss , Pp 106134- (2020)
Phthalic acid esters (PAE) are widely used during chemical synthesis and do not form covalent linkages with products. It has been reported that exposure to PAE affects the immune response. However, their effect on antibody concentrations in children
Externí odkaz:
https://doaj.org/article/717b870ebffc4fe4bd5fbbcf4efd030e
Publikováno v:
iScience, Vol 2, Iss , Pp 210-220 (2018)
Summary: TUC338 is an ultraconserved long non-coding RNA that contributes to transformed cell growth in hepatocellular carcinoma (HCC). Genomic regions of TUC338 occupancy were enriched in unique or known binding motifs homologous to the tumor suppre
Externí odkaz:
https://doaj.org/article/18eac2b0866643df803ee9e72e569e73
Autor:
Hui-Ju Wen
Publikováno v:
Journal of Epidemiology, Vol 27, Iss 11, Pp 516-523 (2017)
Background: Phthalate diesters are commonly used and have been well established as environmental endocrine disruptors. However, few studies have examined their effects on sex steroid hormones in children. We followed children over time to examine the
Externí odkaz:
https://doaj.org/article/e4ba9219476f4540b038a0c63c65b91d
Autor:
Akhilesh Kaushal, Hongmei Zhang, Wilfried J. J. Karmaus, Todd M. Everson, Carmen J. Marsit, Margaret R. Karagas, Shih-Fen Tsai, Hui-Ju Wen, Shu-Li Wang
Publikováno v:
Environmental Health, Vol 16, Iss 1, Pp 1-11 (2017)
Abstract Background In utero arsenic exposure may alter fetal developmental programming by altering DNA methylation, which may result in a higher risk of disease in later life. We evaluated the association between in utero arsenic exposure and DNA me
Externí odkaz:
https://doaj.org/article/abe5c6719fb14859b0134ee501ca41b4
Autor:
Christopher J. Halbrook, Hui-Ju Wen, Jeanine M. Ruggeri, Kenneth K. Takeuchi, Yaqing Zhang, Marina Pasca di Magliano, Howard C. Crawford
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 3, Iss 1, Pp 99-118 (2017)
Background & Aims: Mitogen-activated protein kinase (MAPK) signaling in the exocrine pancreas has been extensively studied in the context of pancreatic cancer, where its potential as a therapeutic target is limited by acquired drug resistance. Howeve
Externí odkaz:
https://doaj.org/article/c9f5121cda804402acbba4c5ea4420b5
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0210708 (2019)
BackgroundPerfluoroalkyl substance (PFAS) exposure was found associated with atopic diseases. Atopic dermatitis (AD) is a childhood skin disorder. However, the effect of interaction between PFASs and glutathione S-transferase (GST) T1/M1 genotype on
Externí odkaz:
https://doaj.org/article/f0b096b1acf2430ba73fd32c4e6716a9